Results 121 to 130 of about 4,001,392 (250)

Structural and Molecular Mechanisms of Gap Junction Remodeling in Epicardial Border Zone Myocytes following Myocardial Infarction [PDF]

, 2009
Fabien Kieken, Nancy Mutsaers, Elena Dolmatova, Kelly L. Virgil, Andrew L. Wit, Admir Kellezi, Bethany J. Hirst-Jensen, Heather S. Duffy, Paul L. Sorgen   +8 more
openalex   +1 more source

Molecular mechanism of drug inhibition of URAT1. [PDF]

Nat Commun
Yu Z, Hu T, Su J, Zhao J, Li R, Ma Q, Chen Q, Bai Q, Dong Y, Yuan P, Li N, Zhang XC, Zhao Y.   +12 more
europepmc   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Nephroprotective Effect of Zingerone against CCl₄‐Induced Renal Toxicity in Swiss Albino Mice: Molecular Mechanism [PDF]

, 2018
Mohammed M. Safhi
openalex   +1 more source

Heart Regeneration and Repair: Molecular Mechanism and Therapeutic Targets. [PDF]

MedComm (2020)
Liu M, Peng T, Yu R, Wang K, Wang D, Jia X, Zhang Y, Hu J, Qi B, Li Y.   +9 more
europepmc   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Molecular Mechanism of Pathogenesis and Management of Diabetic Nephropathy

, 2017
Yamini BT
openalex   +1 more source

Molecular mechanism for direct actin force-sensing by α-catenin

, 2020
Lin Mei, Santiago Espinosa de los Reyes, Matthew J. Reynolds, Rachel Leicher, Shixin Liu, Gregory M. Alushin   +5 more
openalex   +1 more source

Targeting Molecular and Cellular Inhibitory Mechanisms for Improvement of Antitumor Memory Responses Reactivated by Tumor Cell Vaccine [PDF]

, 2007
W. Scott Webster, R. Houston Thompson, Kimberley J. Harris, Xavier Frigola, Susan M. Kuntz, Brant A. Inman, Haidong Dong   +6 more
openalex   +1 more source

Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review). [PDF]

Int J Mol Med
Zhao X, Wang P.
europepmc   +1 more source