Results 51 to 60 of about 4,145,178 (349)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Regulatory roles of an sRNA derived from the 5´ UTR and sequence internal to lapA in Pseudomonas aeruginosa PAO1

Microbiology Spectrum
Several key virulence factors of Pseudomonas aeruginosa are regulated by quorum-sensing systems, small noncoding RNAs (sRNAs), and environmental stress, leading to a high mortality rate.
Xiaojuan Tan, Jingjing Xiao, Qianqian Liu, Ting Yang, Dandan Feng, Ruyi Zheng, Liping Luo, Xi Cheng, Dongsheng Du, Minghui Li, Jinwei Zhou, Guoping Zhu   +11 more
doaj   +1 more source

Towards molecular control of elementary reactions in zeolite catalysis by advanced molecular simulations mimicking operating conditions [PDF]

, 2016
Zeolites are the workhorses of today's chemical industry. For decades they have been successfully applied, however many features of zeolite catalysis are only superficially understood and in particular the kinetics and mechanism of individual reaction ...
Bailleul, Simon, De Wispelaere, Kristof, Van Speybroeck, Veronique   +2 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Effects of the vfm quorum-sensing system on the phenotypic features and virulence of Dickeya zeae WH1

Biofilm
mailto:Soft rot caused by Dickeya zeae is an important bacterial disease affecting rice and other plants around the world. Several studies found that the specific virulence factor-modulating quorum sensing (vfm-QS) system is present in bacteria.
Xiaojuan Tan, Ting Yang, Minglong Wu, Liping Luo, Ruyi Zheng, Qianqian Liu, Guoping Zhu, Yang Sun   +7 more
doaj   +1 more source

Insights into the molecular mechanism of Sjogren's syndrome [PDF]

, 2017
Sjogren’s syndrome (SS) is a chronic autoimmune disease, that affects primarily salivary and lacrimal glands, leading to increased morbidity. Recent studies indicate that loss of salivary gland function is associated with defective cell polarity ...
Langara, Hans A.
core  

Molecular mechanisms of parturition

Infectious Diseases in Obstetrics and Gynecology, 1997
The initial signal for triggering human parturition might be fetal but of trophoblastic origin. Concomitantly, this placental signal would have as its target not only the uterus but also the fetus by activating its hypothalamo-pituitary-adrenocortical axis.
openaire   +2 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Chlorpromazine Efficiently Treats the Crisis of Pheochromocytoma: Four Case Reports and Literature Review

Frontiers in Cardiovascular Medicine, 2021
Pheochromocytoma multisystem crisis (PMC) is a potentially lethal emergency due to catecholamine secretion. The condition manifests as severe hypertension to intractable cardiogenic shock and has a high mortality rate.
James Jiqi Wang, James Jiqi Wang, Zuowen He, Zuowen He, Yan Yang, Bo Yu, Bo Yu, Hong Wang, Hong Wang, Hu Ding, Hu Ding, Guanglin Cui, Guanglin Cui, Luyun Wang, Luyun Wang, Dao Wen Wang, Dao Wen Wang, Jiangang Jiang, Jiangang Jiang   +18 more
doaj   +1 more source

Molecular Motors Interacting with Their Own Tracks

, 2007
Dynamics of molecular motors that move along linear lattices and interact with them via reversible destruction of specific lattice bonds is investigated theoretically by analyzing exactly solvable discrete-state ``burnt-bridge'' models.
A. Y. Morozov, Alexander Yu. Morozov, Anatoly B. Kolomeisky, M. N. Artyomov, Max N. Artyomov   +4 more
core   +1 more source