Results 41 to 50 of about 14,308,960 (385)
Nature Communications, 2018 Methods to study anti-cancer drugs cytotoxicity are often low throughput and rely on population average. Here the authors present an automated image-based cytometry method to quantify multiple cytotoxicity parameters in single cells, and use it to study ...
Jone Michelena +5 more
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Author Correction: Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs
Scientific Data, 2020 A Correction to this paper has been published: https://doi.org/10.1038/s41597-020-00759 ...
Egor Marin +12 more
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Communications Chemistry, 2023 Proteorhodopsins (PRs), bacterial light-driven outward proton pumps comprise the first discovered and largest family of rhodopsins, they play a significant role in life on the Earth.
Ivan S. Okhrimenko +28 more
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Emerging Microbes and Infections, 2021 African swine fever virus (ASFV) is the causal agent of a fatal disease of domestic swine for which no effective antiviral drugs are available. Recently, it has been shown that microtubule-targeting agents hamper the infection cycle of different viruses.
Samvel Sirakanyan +19 more
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The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway
Molecular and Cellular Biology, 2020 The KEAP1-NRF2 pathway is the principal protective response to oxidative and electrophilic stresses. Under homeostatic conditions, KEAP1 forms part of an E3 ubiquitin ligase, which tightly regulates the activity of the transcription factor NRF2 by ...
Liam Baird, Masayuki Yamamoto
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Photocarcinogenesis--molecular mechanisms.
Collegium antropologicum, 2007 The carcinogenicity (photocarcinogenicity) of sunlight to human skin has been recognized more than a century ago. Last decades numerous experimental studies show that UV rays damage DNA, cause gene mutations leading to the development of malignant tumors such basal cell carcinomas, squamous cell carcinomas and melanomas.
Gruber, Franjo +6 more
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Molecular mechanisms of parturition [PDF]
Infectious Diseases in Obstetrics and Gynecology, 1997 The initial signal for triggering human parturition might be fetal but of trophoblastic origin. Concomitantly, this placental signal would have as its target not only the uterus but also the fetus by activating its hypothalamo-pituitary-adrenocortical axis.
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The molecular genetics and cellular mechanisms underlying pulmonary arterial hypertension [PDF]
, 2012 Pulmonary arterial hypertension (PAH) is an incurable disorder clinically characterised by a sustained elevation of mean arterial pressure in the absence of systemic involvement.
Machado, Rajiv
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Molecular model of a sensor of two-component signaling system
Scientific Reports, 2021 Two-component systems (TCS) are widespread signaling systems present in all domains of life. TCS typically consist of a signal receptor/transducer and a response regulator.
Yury L. Ryzhykau +21 more
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Novel Molecular Mechanisms in the Development of Non-Alcoholic Steatohepatitis. [PDF]
, 2016 Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease in adults and children worldwide. NAFLD has become a severe health issue and it can progress towards a more severe form of the disease, the non-alcoholic ...
Feldstein, Ariel E, Povero, Davide
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