Results 21 to 30 of about 2,276,422 (251)

Erythropoietin mediates brain-vascular-kidney crosstalk and may be a treatment target for pulmonary and resistant essential hypertension

open access: yesClinical and Experimental Hypertension, 2017
Organ crosstalk pathways represent the next frontier for target-mining in molecular medicine for existing syndromes. Pulmonary hypertension and resistant essential hypertension are syndromes that have been proven elusive in etiology, and frequently ...
Emine Meltem Onal   +5 more
doaj   +1 more source

E. I. SHWARTZ: AT THE ORIGINS OF MOLECULAR MEDICINE

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2020
Eugene I. Schwartz (1940–2003), the first head of the Department of Molecular Genetic Technologies of the Research Center of the Pavlov University, a well-known geneticist, stood at the origins of molecular medicine in Russia. The results of the research
S. N. Pchelina
doaj   +1 more source

Revolutionizing the understanding of acupoint biology and acupuncture mechanisms through spatial omics: current perspectives and future directions

open access: yesFrontiers in Medicine
Characterizing how localized physical stimulation at acupoints elicits systemic therapeutic effects is essential to understanding acupuncture biology.
Xinzhi Guo   +9 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Sudden Cardiac Death in the Young: State-of-the-Art Review in Molecular Autopsy

open access: yesCurrent Issues in Molecular Biology
Sudden cardiac death (SCD) is defined as unexpected death due to a cardiac cause that occurs rapidly. Despite the identification of prevention strategies, SCD remains a serious public health problem worldwide, accounting for 15–20% of all deaths, and is ...
Cecilia Salzillo   +2 more
doaj   +1 more source

Le patient « actionnable » de la médecine personnalisée

open access: yesSocio-anthropologie, 2014
Personalized Medicine, the new motto of healthcare policy worldwide, is undermined by an ambiguous definition of “personalization”. On the one hand, Personalized Medicine promises that from now on, healthcare systems will focus on patients as whole ...
Xavier Guchet
doaj   +1 more source

Molecular Forensic Medicine: An Overview

open access: yesNational Board of Examinations Journal of Medical Sciences, 2023
Molecular autopsy or Molecular Forensic Medicine is gaining importance across the globe in both developed and developing countries. This is relatively less thought-out or discussed in the Indian scenario.
Kattamreddy Ananth Rupesh   +1 more
doaj   +1 more source

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille   +9 more
wiley   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger   +7 more
wiley   +1 more source

Revolutionizing Healthcare: The Proteomics Paradigm in Molecular Medicine

open access: yesPakistan Journal of Medicine and Dentistry
Proteomics, the comprehensive study of function, composition, structures, and interactions of proteins in biological systems, has emerged as a revolutionary force in the field of molecular medicine.
Yamna Khurshid
doaj   +1 more source

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