Results 1 to 10 of about 3,797,685 (248)
Molecular Mimicry and Uveitis [PDF]
Frontiers in Immunology, 2020 Molecular or antigenic mimicry is a term for the similarity of different antigens, which can be confused by the immune system. Antigen recognition by antibodies and T cell receptors is specific, but not restricted to a single antigen. Both types of receptors specifically recognize antigens and are expressed with a very high but still restricted ...
Wildner, Gerhild +1 more
semanticscholar +9 more sources
Molecular mimicry and cancer vaccine development. [PDF]
Mol Cancer, 2023 AbstractBackgroundThe development of cancer immunotherapeutic strategies relies on the identification and validation of optimal target tumor antigens, which should be tumor-specific as well as able to elicit a swift and potent anti-tumor immune response. The vast majority of such strategies are based on tumor associated antigens (TAAs) which are shared
Tagliamonte M +6 more
europepmc +6 more sources
Visiting Molecular Mimicry Once More: Pathogenicity, Virulence, and Autoimmunity. [PDF]
Microorganisms, 2023 The concept of molecular mimicry describes situations in which antigen sharing between parasites and hosts could benefit pathogen evasion from host immune responses.
Martins YC +2 more
europepmc +2 more sources
Incorporating the Molecular Mimicry of Environmental Antigens into the Causality of Autoimmune Hepatitis. [PDF]
Dig Dis Sci, 2023 Molecular mimicry between foreign and self-antigens has been implicated as a cause of autoimmune hepatitis in experimental models and cross-reacting antibodies in patients.
Czaja AJ.
europepmc +2 more sources
Potential clinical implications of molecular mimicry-induced autoimmunity. [PDF]
Immun Inflamm DisMolecular mimicry is hypothesized to be a mechanism by which autoimmune diseases are triggered. It refers to sequence or structural homology between foreign antigens and self‐antigens, which can activate cross‐reactive lymphocytes that attack host ...
Suliman BA.
europepmc +2 more sources
Molecular mimicry and autoimmunity
Journal of Autoimmunity, 2018 Molecular mimicry is one of the leading mechanisms by which infectious or chemical agents may induce autoimmunity. It occurs when similarities between foreign and self-peptides favor an activation of autoreactive T or B cells by a foreign-derived antigen in a susceptible individual.
Rojas Quintana, Manuel Eduardo +9 more
openaire +4 more sources
Molecular mimicry and autoimmunity in the time of COVID-19. [PDF]
J Autoimmun, 2023 Rojas M +6 more
europepmc +2 more sources
Microbiome, Parkinson’s Disease and Molecular Mimicry [PDF]
Cells, 2019 Parkinson’s Disease (PD) is typically classified as a neurodegenerative disease affecting the motor system. Recent evidence, however, has uncovered the presence of Lewy bodies in locations outside the CNS, in direct contact with the external environment, including the olfactory bulbs and the enteric nervous system.
Miraglia, Fabiana, Colla, Emanuela
openaire +4 more sources
Molecular Mimicry in Multiple Sclerosis
, 2007 One of the most common demyelinating central nervous system (CNS) diseases in humans is multiple sclerosis (MS). The disease can be very debilitating with vision loss, motor and sensory disturbances, and cognitive impairment. The clinical course may present as a relapsing-remitting disease course, a progressive disease course, or a combination thereof.
Jane E. Libbey +2 more
openalex +4 more sources
Interplay between the Chaperone System and Gut Microbiota Dysbiosis in Systemic Lupus Erythematosus Pathogenesis: Is Molecular Mimicry the Missing Link between Those Two Factors? [PDF]
Int J Mol Sci: Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease characterized by self-immune tolerance breakdown and the production of autoantibodies, causing the deposition of immune complexes and triggering inflammation and immune-mediated ...
Vitale AM +8 more
europepmc +3 more sources