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Molecular Mimicry and Uveitis [PDF]
Frontiers in Immunology, 2020 Molecular or antigenic mimicry is a term for the similarity of different antigens, which can be confused by the immune system. Antigen recognition by antibodies and T cell receptors is specific, but not restricted to a single antigen.
Gerhild Wildner +1 more
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Molecular mimicry in the pathogenesis of autoimmune rheumatic diseases
Journal of Translational AutoimmunityAutoimmune rheumatic diseases (ARDs) are a heterogeneous group of conditions characterized by excessive and misdirected immune responses against the body's own musculoskeletal tissues.
Michaela Fehringer, Thomas Vogl
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Molecular Mimicry in Multiple Sclerosis
, 2007 One of the most common demyelinating central nervous system (CNS) diseases in humans is multiple sclerosis (MS). The disease can be very debilitating with vision loss, motor and sensory disturbances, and cognitive impairment. The clinical course may present as a relapsing-remitting disease course, a progressive disease course, or a combination thereof.
Libbey, Jane E. +2 more
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Molecular mimicry and immune thrombocytopenia [PDF]
Blood, 2009 In this issue of Blood, Zhang and colleagues show evidence that many thrombocytopenic patients infected with HCV have autoantibodies specific for a defined peptide sequence in platelet membrane glycoprotein IIIa. These autoantibodies appear to be the result of an immune response mounted against one or more peptides present in the HCV core envelope ...
Richard H. Aster
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PLoS ONE, 2022 Microbial mimicry of the host proteins/peptides can elicit host auto-reactive T- or B-cells resulting in autoimmune disease(s). Since intrinsically disordered protein regions (IDPRs) are involved in several host cell signaling and PPI networks, molecular
Anjali Garg +3 more
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AIMS Allergy and ImmunologyThe immune system is meant to protect against invading microbes. Although this system is effective against many microbes, some can use molecular mimicry to turn the immune system against the host and activate autoimmune responses.
Djo Hasan
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Identification of potential molecular mimicry in pathogen-host interactions [PDF]
PeerJ, 2023 Pathogens have evolved sophisticated strategies to manipulate host signaling pathways, including the phenomenon of molecular mimicry, where pathogen-derived biomolecules imitate host biomolecules.
Kaylee D. Rich +3 more
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The interplay between viral molecular mimicry and host chromatin dynamics
Nucleus, 2023 Molecular mimicry is a commonly used mechanism by viruses to manipulate host cellular machinery and coordinate their life cycles. While histone mimicry is well studied, viruses also employ other mimicry strategies to affect chromatin dynamics.
Shumin Xiao +3 more
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Molecular (epitopic) mimicry phenomenon in Lime arthritis
Научно-практическая ревматология, 2004 Л П Ананьева
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Molecular Plant-Microbe Interactions, 2021 Molecular mimicry is one of the evolutionary strategies that parasites use to manipulate the host metabolism and perform an effective infection. This phenomenon has been observed in several animal and plant pathosystems.
Vinicio Armijos-Jaramillo +3 more
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