Results 181 to 190 of about 3,774,726 (329)

The immunolocalization of HIF‐2α, GLUT1 and CAIX in porcine oviduct during the estrous cycle

open access: yesThe Anatomical Record, Volume 306, Issue 1, Page 176-186, January 2023., 2023
Abstract Oxygen (O2) rates in the oviduct are essential to human and animal reproduction. These rates are regulated by the activity of hypoxia markers such as the hypoxia‐inducible factors (HIFs), the glucose transporters (GLUT), and the carbonic anhydrase (CA).
Ester Párraga‐Ros   +4 more
wiley   +1 more source

Reversible High‐Affinity Binding of Coagulation Factor Xa to Zeolites Induces Accelerated Blood Coagulation

open access: yesAdvanced Science, EarlyView.
A calcium‐dependent, specific biorecognition between coagulation factor Xa (FXa) and zeolite is discovered. It alters the prothrombin activation pathway to a more efficient mechanism by mimicking the FXa/factor Va (FXa/FVa) interaction formed during the natural coagulation cascade.
Chaojie Shi   +9 more
wiley   +1 more source

First clear evidence of Anoplotherium (Mammalia, Artiodactyla) in the Iberian Peninsula: an update on the Iberian anoplotheriines

open access: yesThe Anatomical Record, EarlyView., 2023
Abstract Anoplotheriines (Mammalia, Artiodactyla) were enigmatic, medium‐ to large‐sized ungulates that lived in Western Europe from the late middle Eocene to the earliest Oligocene. The unusual dental and postcranial specializations of these Paleogene mammals have no equivalent in other Cenozoic or contemporaneous artiodactyls on Holarctic landmasses.
Ainara Badiola   +3 more
wiley   +1 more source

SEQUENCE SIMILARITY BETWEEN THYROID SELF-PROTEIN AND HEPATITIS C VIRUS POLYPROTEIN: possible triggering mechanism of autoimmune thyroiditis

open access: yesArquivos de Gastroenterologia
Background - Exposure to viral antigens that share amino acid sequence similar with self- antigens might trigger autoimmune diseases in genetically predisposed individuals, and the molecular mimicry theory suggests that epitope mimicry between the virus ...
Maristella de Araújo Carvalho SOUSA   +2 more
doaj   +1 more source

Deep Learning System Boundary Testing through Latent Space Style Mixing [PDF]

open access: yesarXiv
Evaluating the behavioral frontier of deep learning (DL) systems is crucial for understanding their generalizability and robustness. However, boundary testing is challenging due to their high-dimensional input space. Generative artificial intelligence offers a promising solution by modeling data distribution within compact latent space representations,
arxiv  

Fish Swim Bladder‐Derived ECM Hydrogels Effectively Treat Myocardial Ischemic Injury through Immunomodulation and Angiogenesis

open access: yesAdvanced Science, EarlyView.
A unique hydrogel based on extracellular matrix from fish swim bladder, which is suitable for transcatheter delivery and possesses remarkable reparative capabilities for treating heart failure, is developed. It emerges as a multi‐effect factor profoundly influencing inflammation regulation, angiogenesis, and myocardial metabolism.
Yulong Fu   +9 more
wiley   +1 more source

Come together over me: Cells that form the dermatocranium and chondrocranium in mice

open access: yesThe Anatomical Record, EarlyView., 2023
Abstract Most bone develops either by intramembranous ossification where bone forms within a soft connective tissue, or by endochondral ossification by way of a cartilage anlagen or model. Bones of the skull can form endochondrally or intramembranously or represent a combination of the two types of ossification.
M. Kathleen Pitirri   +5 more
wiley   +1 more source

Mimicry of molecular glues using dual covalent chimeras

open access: yesNature Communications
A special class of proximity inducing bifunctional molecules/chimeras called molecular glues leverage positive co-operativity to stabilize ternary complex formation and induce a biological response.
Eden Kapcan   +6 more
doaj   +1 more source

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