Results 11 to 20 of about 2,281 (156)
Potential Autoimmunity Resulting from Molecular Mimicry between SARS-CoV-2 Spike and Human Proteins
Viruses, 2022 Molecular mimicry between viral antigens and host proteins can produce cross-reacting antibodies leading to autoimmunity. The coronavirus SARS-CoV-2 causes COVID-19, a disease curiously resulting in varied symptoms and outcomes, ranging from asymptomatic
Janelle Nunez-Castilla +10 more
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The molecular mimicry and COVID-19
Инфекция и иммунитет, 2023 A significant part of the complications of COVID-19 and manifestations of post-COVID syndrome is associated with autoimmune reactions caused by SARS-CoV-2.
Veronika Zorina
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Genome-wide identification of molecular mimicry candidates in parasites. [PDF]
PLoS ONE, 2011 Among the many strategies employed by parasites for immune evasion and host manipulation, one of the most fascinating is molecular mimicry. With genome sequences available for host and parasite, mimicry of linear amino acid epitopes can be investigated ...
Philipp Ludin +2 more
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Carbohydrate Mimetic Peptides for Pan Anti-Tumor Responses
Frontiers in Immunology, 2014 Molecular mimicry is fundamental to biology which transcends to many disciplines ranging from immune pathology to drug design. Structural characterization of molecular partners has provided insight into the origins and relative importance of ...
Thomas eKieber-Emmons +4 more
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SARS-CoV-2-Induced Immunosuppression: A Molecular Mimicry Syndrome
Global Medical Genetics, 2022 Background Contrary to immunological expectations, decay of adaptive responses against severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) characterizes recovered patients compared with patients who had a severe disease course or died following ...
Darja Kanduc
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Molecular Mimicry between Respiratory Syncytial Virus F Antigen and the Human Proteome
Global Medical Genetics, 2023 This study examined respiratory syncytial virus (RSV) F glycoprotein (gp) antigen for molecular mimicry with the human proteome. It was found that the viral antigen presents an impressive number of pentapeptides (namely, 525 out of 570) in common with ...
Darja Kanduc
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Journal of Diabetology, 2023 Introduction: Multiple mechanisms were proposed for the etiopathogenesis of type 1 diabetes mellitus (T1DM). An interplay between genetic, environmental, and immunological factors leads to generate autoantibodies against glutamic acid decarboxylase 65 ...
Ashish Gautam +4 more
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Arquivos de Neuro-Psiquiatria, 2023 Background Evidence indicates a strong link between Zika virus (ZikV) and neurological complications. Acute myelitis, optic neuritis, polyneuropathy, and encephalomyelitis that mimic inflammatory idiopathic demyelination disorders (IIDD) after ZikV ...
Laise Carolina França +15 more
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Molecular mimicry and cancer vaccine development
Molecular Cancer, 2023 Background The development of cancer immunotherapeutic strategies relies on the identification and validation of optimal target tumor antigens, which should be tumor-specific as well as able to elicit a swift and potent anti-tumor immune response.
Maria Tagliamonte +6 more
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Visiting Molecular Mimicry Once More: Pathogenicity, Virulence, and Autoimmunity
Microorganisms, 2023 The concept of molecular mimicry describes situations in which antigen sharing between parasites and hosts could benefit pathogen evasion from host immune responses.
Yuri Chaves Martins +2 more
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