Molecular mimicry and autoimmunity
Journal of Autoimmunity, 2018 Molecular mimicry is one of the leading mechanisms by which infectious or chemical agents may induce autoimmunity. It occurs when similarities between foreign and self-peptides favor an activation of autoreactive T or B cells by a foreign-derived antigen in a susceptible individual.
Rojas Quintana, Manuel Eduardo +9 more
semanticscholar +6 more sources
Molecular mimicry and autoimmunity in the time of COVID-19. [PDF]
J Autoimmun, 2023 Infectious diseases are commonly implicated as potential initiators of autoimmune diseases (ADs) and represent the most commonly known factor in the development of autoimmunity in susceptible individuals.
Rojas M +6 more
europepmc +2 more sources
Incorporating the Molecular Mimicry of Environmental Antigens into the Causality of Autoimmune Hepatitis. [PDF]
Dig Dis Sci, 2023 Molecular mimicry between foreign and self-antigens has been implicated as a cause of autoimmune hepatitis in experimental models and cross-reacting antibodies in patients.
Czaja AJ.
europepmc +2 more sources
Molecular mimicry in multisystem inflammatory syndrome in children. [PDF]
NatureMultisystem inflammatory syndrome in children (MIS-C) is a severe, post-infectious sequela of SARS-CoV-2 infection1,2, yet the pathophysiological mechanism connecting the infection to the broad inflammatory syndrome remains unknown.
Bodansky A +31 more
europepmc +2 more sources
Hepatitis C Virus and Molecular Mimicry [PDF]
PathogensThis review delves into the interactions between hepatitis C virus (HCV) and the host immune system, shedding light on how by using the mechanism of molecular mimicry, the virus strategically evades the immune system, resulting in a cascade of diverse ...
Lynette Goh, Nanda Kerkar
doaj +2 more sources
Evidence for Molecular Mimicry between SARS-CoV-2 and Human Antigens: Implications for Autoimmunity in COVID-19. [PDF]
Autoimmune DisAs for other viral diseases, the mechanisms behind the apparent relationship between COVID-19 and autoimmunity are yet to be clearly defined. Molecular mimicry, the existence of sequence and/or conformational homology between viral and human antigens ...
Arévalo-Cortés A +2 more
europepmc +2 more sources
Autoantibodies and Molecular Mimicry in Alphavirus Chronic Arthritis: A Systematic Review [PDF]
PathogensChronic arthritis following arthritogenic alphavirus infections presents symptoms resembling autoimmune rheumatic diseases, raising questions about the underlying mechanisms, including molecular mimicry and autoantibody production. This systematic review
Nosipho Zanele Masoto +1 more
doaj +2 more sources
Molecular Mimicry between Meningococcal B Factor H-Binding Protein and Human Proteins [PDF]
Global Medical Genetics, 2023 This study calls attention on molecular mimicry and the consequent autoimmune cross reactivity as the molecular mechanism that can cause adverse events following meningococcal B vaccination and warns against active immunizations based on entire antigen.
Darja Kanduc
doaj +2 more sources
miPepBase: A Database of Experimentally Verified Peptides Involved in Molecular Mimicry
Frontiers in Microbiology, 2017 Autoimmune diseases emerge due to several reasons, of which molecular mimicry i.e., similarity between the host's and pathogen's interacting peptides is an important reason. In the present study we have reported a database of only experimentally verified
Anjali Garg +3 more
doaj +2 more sources
Autoimmune Diseases and Molecular Mimicry in Tuberculosis [PDF]
BiologyComorbidities in tuberculosis patients are increasing annually. Autoimmune pathology may influence the diagnosis and treatment of tuberculosis (TB). However, the molecular mimicry between Mycobacterium tuberculosis (Mtb) and human autoantigens is an ...
Leonid P. Churilov +5 more
doaj +2 more sources