Results 11 to 20 of about 3,798,542 (370)
Potential Autoimmunity Resulting from Molecular Mimicry between SARS-CoV-2 Spike and Human Proteins
Viruses, 2022 SARS-CoV-2 causes COVID-19, a disease curiously resulting in varied symptoms and outcomes, ranging from asymptomatic to fatal. Autoimmunity due to cross-reacting antibodies resulting from molecular mimicry between viral antigens and host proteins may ...
Janelle Nunez-Castilla +10 more
semanticscholar +3 more sources
Molecular Mimicry: a Paradigm of Host-Microbe Coevolution Illustrated by Legionella
mBio, 2020 Through coevolution with host cells, microorganisms have acquired mechanisms to avoid the detection by the host surveillance system and to use the cell’s supplies to establish themselves.
S. Mondino, S. Schmidt, C. Buchrieser
semanticscholar +3 more sources
The interplay between viral molecular mimicry and host chromatin dynamics. [PDF]
Nucleus, 2023 Molecular mimicry is a commonly used mechanism by viruses to manipulate host cellular machinery and coordinate their life cycles. While histone mimicry is well studied, viruses also employ other mimicry strategies to affect chromatin dynamics.
Xiao S, Wang Y, Shan S, Zhou Z.
europepmc +2 more sources
miPepBase: A Database of Experimentally Verified Peptides Involved in Molecular Mimicry
Frontiers in Microbiology, 2017 Autoimmune diseases emerge due to several reasons, of which molecular mimicry i.e., similarity between the host's and pathogen's interacting peptides is an important reason. In the present study we have reported a database of only experimentally verified
Anjali Garg +3 more
semanticscholar +3 more sources
Guillain-Barré syndrome: expanding the concept of molecular mimicry. [PDF]
Trends Immunol, 2022 Laman JD +3 more
europepmc +2 more sources
Identification of potential molecular mimicry in pathogen-host interactions. [PDF]
PeerJ, 2023 Pathogens have evolved sophisticated strategies to manipulate host signaling pathways, including the phenomenon of molecular mimicry, where pathogen-derived biomolecules imitate host biomolecules.
Rich KD +3 more
europepmc +3 more sources
T Cell Allorecognition via Molecular Mimicry [PDF]
Immunity, 2009 T cells often alloreact with foreign human leukocyte antigens (HLA). Here we showed the LC13 T cell receptor (TCR), selected for recognition on self-HLA-B( *)0801 bound to a viral peptide, alloreacts with B44 allotypes (HLA-B( *)4402 and HLA-B( *)4405) bound to two different allopeptides.
W.A. Macdonald +18 more
openalex +6 more sources
Frontiers in Microbiology, 2017 Understanding etiology of autoimmune diseases has been a great challenge for designing drugs and vaccines. The pathophysiology of many autoimmune diseases may be attributed to molecular mimicry provoked by microbes.
S. Pahari +5 more
semanticscholar +3 more sources
Molecular mimicry as a mechanism of viral immune evasion and autoimmunity. [PDF]
Nat CommunMimicry of host protein structures, or ‘molecular mimicry’, is a common mechanism employed by viruses to evade the host’s immune system. Short linear amino acid (AA) molecular mimics can elicit cross-reactive antibodies and T cells from the host, but the
Maguire C +7 more
europepmc +2 more sources
Hepatitis C Virus and Molecular Mimicry. [PDF]
PathogensThis review delves into the interactions between hepatitis C virus (HCV) and the host immune system, shedding light on how by using the mechanism of molecular mimicry, the virus strategically evades the immune system, resulting in a cascade of diverse ...
Goh L, Kerkar N.
europepmc +2 more sources