Identification of potential molecular mimicry in pathogen-host interactions [PDF]
PeerJ, 2023 Pathogens have evolved sophisticated strategies to manipulate host signaling pathways, including the phenomenon of molecular mimicry, where pathogen-derived biomolecules imitate host biomolecules.
Kaylee D. Rich +3 more
doaj +3 more sources
The interplay between viral molecular mimicry and host chromatin dynamics [PDF]
Nucleus, 2023 Molecular mimicry is a commonly used mechanism by viruses to manipulate host cellular machinery and coordinate their life cycles. While histone mimicry is well studied, viruses also employ other mimicry strategies to affect chromatin dynamics.
Shumin Xiao +3 more
doaj +2 more sources
Incorporating the Molecular Mimicry of Environmental Antigens into the Causality of Autoimmune Hepatitis [PDF]
Dig Dis Sci, 2023 Molecular mimicry between foreign and self-antigens has been implicated as a cause of autoimmune hepatitis in experimental models and cross-reacting antibodies in patients.
A. Czaja
semanticscholar +2 more sources
Hepatitis C Virus and Molecular Mimicry [PDF]
PathogensThis review delves into the interactions between hepatitis C virus (HCV) and the host immune system, shedding light on how by using the mechanism of molecular mimicry, the virus strategically evades the immune system, resulting in a cascade of diverse ...
Lynette Goh, Nanda Kerkar
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Molecular mimicry in multisystem inflammatory syndrome in children [PDF]
NatureMultisystem inflammatory syndrome in children (MIS-C) is a severe, post-infectious sequela of SARS-CoV-2 infection1,2, yet the pathophysiological mechanism connecting the infection to the broad inflammatory syndrome remains unknown.
Aaron Bodansky +30 more
semanticscholar +2 more sources
Molecular Mimicry between Meningococcal B Factor H-Binding Protein and Human Proteins [PDF]
Global Medical Genetics, 2023 This study calls attention on molecular mimicry and the consequent autoimmune cross reactivity as the molecular mechanism that can cause adverse events following meningococcal B vaccination and warns against active immunizations based on entire antigen.
Darja Kanduc
doaj +2 more sources
Molecular Mimicry between Respiratory Syncytial Virus F Antigen and the Human Proteome [PDF]
Global Medical Genetics, 2023 This study examined respiratory syncytial virus (RSV) F glycoprotein (gp) antigen for molecular mimicry with the human proteome. It was found that the viral antigen presents an impressive number of pentapeptides (namely, 525 out of 570) in common with ...
Darja Kanduc
doaj +2 more sources
Autoimmune Diseases and Molecular Mimicry in Tuberculosis [PDF]
BiologyComorbidities in tuberculosis patients are increasing annually. Autoimmune pathology may influence the diagnosis and treatment of tuberculosis (TB). However, the molecular mimicry between Mycobacterium tuberculosis (Mtb) and human autoantigens is an ...
Leonid P. Churilov +5 more
doaj +2 more sources
Molecular mimicry in the pathogenesis of autoimmune rheumatic diseases [PDF]
Journal of Translational AutoimmunityAutoimmune rheumatic diseases (ARDs) are a heterogeneous group of conditions characterized by excessive and misdirected immune responses against the body's own musculoskeletal tissues.
Michaela Fehringer, Thomas Vogl
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Molecular mimicry between parasites and cancer: a novel approach for developing cancer vaccines and therapeutic antibodies [PDF]
Cancer Immunology, ImmunotherapyCancer is one of the most dreaded diseases worldwide. Conventional treatments such as surgery, chemotherapy, and radiotherapy have limitations and adverse effects. Cancer immunotherapy and targeted therapies offer new treatment options.
Maha Mohamed Eissa +5 more
doaj +2 more sources