Incorporating the Molecular Mimicry of Environmental Antigens into the Causality of Autoimmune Hepatitis. [PDF]
Dig Dis Sci, 2023 Molecular mimicry between foreign and self-antigens has been implicated as a cause of autoimmune hepatitis in experimental models and cross-reacting antibodies in patients.
Czaja AJ.
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Molecular mimicry in multisystem inflammatory syndrome in children. [PDF]
NatureMultisystem inflammatory syndrome in children (MIS-C) is a severe, post-infectious sequela of SARS-CoV-2 infection1,2, yet the pathophysiological mechanism connecting the infection to the broad inflammatory syndrome remains unknown.
Bodansky A +31 more
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Molecular mimicry in the pathogenesis of autoimmune rheumatic diseases [PDF]
Journal of Translational AutoimmunityAutoimmune rheumatic diseases (ARDs) are a heterogeneous group of conditions characterized by excessive and misdirected immune responses against the body's own musculoskeletal tissues.
Michaela Fehringer, Thomas Vogl
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Evidence for Molecular Mimicry between SARS-CoV-2 and Human Antigens: Implications for Autoimmunity in COVID-19. [PDF]
Autoimmune DisAs for other viral diseases, the mechanisms behind the apparent relationship between COVID-19 and autoimmunity are yet to be clearly defined. Molecular mimicry, the existence of sequence and/or conformational homology between viral and human antigens ...
Arévalo-Cortés A +2 more
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Molecular Mimicry between Meningococcal B Factor H-Binding Protein and Human Proteins [PDF]
Global Medical Genetics, 2023 This study calls attention on molecular mimicry and the consequent autoimmune cross reactivity as the molecular mechanism that can cause adverse events following meningococcal B vaccination and warns against active immunizations based on entire antigen.
Darja Kanduc
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Molecular Mimicry between Respiratory Syncytial Virus F Antigen and the Human Proteome [PDF]
Global Medical Genetics, 2023 This study examined respiratory syncytial virus (RSV) F glycoprotein (gp) antigen for molecular mimicry with the human proteome. It was found that the viral antigen presents an impressive number of pentapeptides (namely, 525 out of 570) in common with ...
Darja Kanduc
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Autoimmune Diseases and Molecular Mimicry in Tuberculosis [PDF]
BiologyComorbidities in tuberculosis patients are increasing annually. Autoimmune pathology may influence the diagnosis and treatment of tuberculosis (TB). However, the molecular mimicry between Mycobacterium tuberculosis (Mtb) and human autoantigens is an ...
Leonid P. Churilov +5 more
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Molecular mimicry between parasites and cancer: a novel approach for developing cancer vaccines and therapeutic antibodies [PDF]
Cancer Immunology, ImmunotherapyCancer is one of the most dreaded diseases worldwide. Conventional treatments such as surgery, chemotherapy, and radiotherapy have limitations and adverse effects. Cancer immunotherapy and targeted therapies offer new treatment options.
Maha Mohamed Eissa +5 more
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Molecular Mimicry: a Paradigm of Host-Microbe Coevolution Illustrated by
mBio, 2020 Through coevolution with host cells, microorganisms have acquired mechanisms to avoid the detection by the host surveillance system and to use the cell’s supplies to establish themselves.
Sonia Mondino +2 more
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Molecular Mimicry Mapping in Streptococcus pneumoniae: Cues for Autoimmune Disorders and Implications for Immune Defense Activation [PDF]
Pathogens, 2023 Streptococcus pneumoniae contributes to a range of infections, including meningitis, pneumonia, otitis media, and sepsis. Infections by this bacterium have been associated with the phenomenon of molecular mimicry, which, in turn, may contribute to the ...
Mutaib M. Mashraqi +6 more
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