Results 21 to 30 of about 3,817,121 (368)

T Cell Allorecognition via Molecular Mimicry [PDF]

Immunity, 2009
T cells often alloreact with foreign human leukocyte antigens (HLA). Here we showed the LC13 T cell receptor (TCR), selected for recognition on self-HLA-B( *)0801 bound to a viral peptide, alloreacts with B44 allotypes (HLA-B( *)4402 and HLA-B( *)4405) bound to two different allopeptides.
W.A. Macdonald, Zhenjun Chen, Stéphanie Gras, Julia K. Archbold, F.E. Tynan, Craig S. Clements, Mandvi Bharadwaj, Lars Kjer‐Nielsen, Philippa M. Saunders, Matthew C. J. Wilce, F. T. Crawford, B. Stadinsky, David C. Jackson, Andrëw G. Brööks, Anthony W. Purcell, John W. Kappler, Scott R. Burrows, Jamie Rossjohn, James McCluskey   +18 more
openalex   +6 more sources

Incorporating the Molecular Mimicry of Environmental Antigens into the Causality of Autoimmune Hepatitis. [PDF]

Dig Dis Sci, 2023
Molecular mimicry between foreign and self-antigens has been implicated as a cause of autoimmune hepatitis in experimental models and cross-reacting antibodies in patients.
Czaja AJ.
europepmc   +2 more sources

Molecular mimicry and autoimmunity in the time of COVID-19. [PDF]

J Autoimmun, 2023
Rojas M, Herrán M, Ramírez-Santana C, Leung PSC, Anaya JM, Ridgway WM, Gershwin ME.   +6 more
europepmc   +2 more sources

Morbid Sequences Suggest Molecular Mimicry between Microbial Peptides and Self-Antigens: A Possibility of Inciting Autoimmunity

Frontiers in Microbiology, 2017
Understanding etiology of autoimmune diseases has been a great challenge for designing drugs and vaccines. The pathophysiology of many autoimmune diseases may be attributed to molecular mimicry provoked by microbes.
Susanta Pahari, Susanta Pahari, Deepyan Chatterjee, Shikha Negi, Jagdeep Kaur, Balvinder Singh, Javed N. Agrewala   +6 more
doaj   +2 more sources

Investigating the disordered regions (MoRFs, SLiMs and LCRs) and functions of mimicry proteins/peptides in silico.

PLoS ONE, 2022
Microbial mimicry of the host proteins/peptides can elicit host auto-reactive T- or B-cells resulting in autoimmune disease(s). Since intrinsically disordered protein regions (IDPRs) are involved in several host cell signaling and PPI networks, molecular
Anjali Garg, Govinda Rao Dabburu, Neelja Singhal, Manish Kumar   +3 more
doaj   +2 more sources

Guillain-Barré syndrome: expanding the concept of molecular mimicry. [PDF]

Trends Immunol, 2022
Laman JD, Huizinga R, Boons GJ, Jacobs BC.   +3 more
europepmc   +2 more sources

Guillain-Barré Syndrome-related campylobacter jejuni in Bangladesh: ganglioside mimicry and cross-reactive antibodies [PDF]

, 2012
BACKGROUND: <br/> Campylobacter jejuni is the predominant antecedent infection in Guillain-Barré syndrome (GBS). Molecular mimicry and cross-reactive immune responses to C.
Endtz, H.P., Gilbert, M., Islam, Z., Jacobs, B.C., Klaij, K., Li, J., Mohammad, Q.D., Talukder, K.A., Tio-Gillen, A.P., van Belkum, A., van Rijs, W., Willison, H.J.   +11 more
core   +17 more sources

SARS-CoV-2 in patients with cancer: possible role of mimicry of human molecules by viral proteins and the resulting anti-cancer immunity [PDF]

, 2021
A few reports suggest that molecular mimicry can have a role in determining the more severe and deadly forms of COVID-19, inducing endothelial damage, disseminated intravascular coagulation, and multiorgan failure.
Burgio S., Cappello F., Conway de Macario E., Macario A. J.   +3 more
core   +1 more source

Molecular (epitopic) mimicry phenomenon in Lime arthritis

Научно-практическая ревматология, 2004
Л П Ананьева
doaj   +2 more sources

Molecular Mimicry between SARS-CoV-2 and Human Endocrinocytes: A Prerequisite of Post-COVID-19 Endocrine Autoimmunity?

Pathophysiology, 2022
Molecular mimicry between human and microbial/viral/parasite peptides is common and has long been associated with the etiology of autoimmune disorders provoked by exogenous pathogens.
L. Churilov, M. G. Normatov, V. Utekhin
semanticscholar   +1 more source