Results 21 to 30 of about 3,908,356 (326)

Molecular Mimicry Mapping in Streptococcus pneumoniae: Cues for Autoimmune Disorders and Implications for Immune Defense Activation [PDF]

Pathogens, 2023
Streptococcus pneumoniae contributes to a range of infections, including meningitis, pneumonia, otitis media, and sepsis. Infections by this bacterium have been associated with the phenomenon of molecular mimicry, which, in turn, may contribute to the ...
Mutaib M. Mashraqi, Ahmad Alzamami, Norah A. Alturki, Saleh Alshamrani, Mousa M. Alshahrani, Hassan H. Almasoudi, Zarrin Basharat   +6 more
doaj   +2 more sources

Molecular mimicry and autoimmunity in the time of COVID-19. [PDF]

J Autoimmun, 2023
Rojas M, Herrán M, Ramírez-Santana C, Leung PSC, Anaya JM, Ridgway WM, Gershwin ME.   +6 more
europepmc   +2 more sources

Morbid Sequences Suggest Molecular Mimicry between Microbial Peptides and Self-Antigens: A Possibility of Inciting Autoimmunity

Frontiers in Microbiology, 2017
Understanding etiology of autoimmune diseases has been a great challenge for designing drugs and vaccines. The pathophysiology of many autoimmune diseases may be attributed to molecular mimicry provoked by microbes.
Susanta Pahari, Susanta Pahari, Deepyan Chatterjee, Shikha Negi, Jagdeep Kaur, Balvinder Singh, Javed N. Agrewala   +6 more
doaj   +2 more sources

Investigating the disordered regions (MoRFs, SLiMs and LCRs) and functions of mimicry proteins/peptides in silico.

PLoS ONE, 2022
Microbial mimicry of the host proteins/peptides can elicit host auto-reactive T- or B-cells resulting in autoimmune disease(s). Since intrinsically disordered protein regions (IDPRs) are involved in several host cell signaling and PPI networks, molecular
Anjali Garg, Govinda Rao Dabburu, Neelja Singhal, Manish Kumar   +3 more
doaj   +2 more sources

Vaccine-induced autoimmunity: the role of molecular mimicry and immune crossreaction

Cellular and Molecular Immunology, 2018
Yahel Segal, Y. Shoenfeld
exaly   +2 more sources

Genes Suggest Ancestral Colour Polymorphisms Are Shared across Morphologically Cryptic Species in Arctic Bumblebees [PDF]

, 2015
email Suzanne orcd idCopyright: © 2015 Williams et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
A Bertsch, A Bertsch, A Cardoso, A Estoup, A Løken, A Papadopoulou, A Pekkarinen, AJ Drummond, Alexandr M. Byvaltsev, AS Skorikov, AS Skorikov, B Pittioni, B Tkalcu, B Tkalcu, BC Schlick-Steiner, BG Svensson, BG Svensson, Björn Cederberg, CD Michener, Claus Rasmussen, Cory S. Sheffield, D Baum, DR Maddison, DV Panfilov, E Krüger, EO Wilson, F Leliaert, Frode Ødegaard, G Talavera, GF Barrowclough, H Friese, H Pringle, H Song, HE Milliron, HM Hines, HM Hines, IC Barro, J Brigham-Grette, J Mallet, J Pons, J-J Zhang, J-X Huang, JC Carolan, Jiaxing Huang, JO Gjershaug, JP Huelsenbeck, JP Strange, K de Queiroz, K Tamura, KJ Gaston, KN Magnacca, KW Richards, KW von Dalla Torre, Leif L. Richardson, M Terzo, MA Duennes, Mikhail V. Berezin, MK Fujita, MP Cristiano, MR Kronforst, MT Monaghan, MT Monaghan, NM Reid, O Radoszkowski, O Vogt, O Vogt, OW Richards, OW Richards, P Pamilo, P Rasmont, P Rasmont, P Rasmont, Paul H. Williams, PDN Hebert, PDN Hebert, PH Williams, PH Williams, PH Williams, PH Williams, PH Williams, PH Williams, PH Williams, PH Williams, PH Williams, PH Williams, R Neumeyer, R Rougerie, RC Plowright, RM Zink, RM Zink, S Ratnasingham, SA Cameron, SA Elias, ST Williams, Suzanne T. Williams, SV Edwards, T De Meulemeester, T Fujisawa, T Lecocq, T Lecocq, T Lecocq, T Lecocq, WF Reinig, WF Reinig, WF Reinig, WP Maddison, Z Rapti, Zuogang Peng   +107 more
core   +23 more sources

Molecular Mimicry between SARS-CoV-2 and Human Endocrinocytes: A Prerequisite of Post-COVID-19 Endocrine Autoimmunity?

Pathophysiology, 2022
Molecular mimicry between human and microbial/viral/parasite peptides is common and has long been associated with the etiology of autoimmune disorders provoked by exogenous pathogens.
L. Churilov, M. G. Normatov, V. Utekhin
semanticscholar   +1 more source

A gut microbial peptide and molecular mimicry in the pathogenesis of type 1 diabetes

bioRxiv, 2022
Type 1 Diabetes (T1D) is an autoimmune disease characterized by the destruction of pancreatic β-cells. One of the earliest aspects of this process is development of autoantibodies and T-cells directed at an epitope in the B-chain of insulin (insB:9-23 ...
K. Girdhar, Qian Huang, I-Ting Chow, T. Vatanen, C. Brady, Amol Raisingani, P. Autissier, M. Atkinson, W. Kwok, C. Kahn, E. Altindis   +10 more
semanticscholar   +1 more source

A Novel In Silico Method for Molecular Mimicry Detection Finds a Formin with the Potential to Manipulate the Maize Cell Cytoskeleton

Molecular Plant-Microbe Interactions, 2021
Molecular mimicry is one of the evolutionary strategies that parasites use to manipulate the host metabolism and perform an effective infection. This phenomenon has been observed in several animal and plant pathosystems.
Vinicio Armijos-Jaramillo, Nicole Espinosa, Karla Vizcaíno, Daniela Santander-Gordón   +3 more
doaj   +1 more source

Conformational Plasticity of HLA-B27 Molecules Correlates Inversely With Efficiency of Negative T Cell Selection [PDF]

, 2020
The development of autoimmune disorders is incompletely understood. Inefficient thymic T cell selection against self-peptides presented by major histocompatibility antigens (HLA in humans) may contribute to the emergence of auto-reactive effector cells ...
Loll, Bernhard, Rückert, Christine, Uchanska-Ziegler, Barbara, Ziegler, Andreas   +3 more
core   +1 more source