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2007
Molecular mimicry is the occurrence of common B or T cell reactive epitopes between microorganisms or environmental agents and the host, and the pathogenic consequence of such cross-reactivity. Molecular mimicry has been demonstrated to occur in several different forms including complete identity at the protein level, homology at the protein level ...
Robert S. Fujinami, Lisa K. Peterson
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Molecular mimicry is the occurrence of common B or T cell reactive epitopes between microorganisms or environmental agents and the host, and the pathogenic consequence of such cross-reactivity. Molecular mimicry has been demonstrated to occur in several different forms including complete identity at the protein level, homology at the protein level ...
Robert S. Fujinami, Lisa K. Peterson
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Tropomyosin and molecular mimicry
Parasitology Today, 1991cyst investiture in nonmuscle tropo- myosin may play a role in immune evasion in the snail host by protecting the sporocyst from amoebocyte attack. If true, this would be a prime example of molecular mimicry in its full and original sense s , which links common structures to the host-parasite relationship.
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Molecular Mimicry in Mercury Toxicology
Chemical Research in Toxicology, 2006Molecular mimicry occurs when one molecular entity is "mistaken" for another by cellular or other biological processes, and is thought to arise from structural similarities between the two molecules in question. It has been postulated by others to be important in the mechanism of uptake of toxic metal species into living tissues.
Hoffmeyer, R. +6 more
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Malaria and ovalocytosis — molecular mimicry?
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1991Two recently published reports have described findings which will have a profound impact on the understanding of molecular mechanisms of human resistance to malaria infection. In Melanesian ovalocytosis, a genetic polymorphism found in Papua New Guinea and parts of South East Asia, the red cells are highly resistant to invasion by various species of ...
Paul Ruff, A. Husain-Chishti
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Molecular Mimicry and Diabetes
1989Insulin-dependent diabetes (IDDM) often develops early in life and is associated with lifelong insulin treatment, a reduced life span, and serious long-term complications (Borch-Johnsen et al. 1986). Other forms of diabetes exist (National Diabetes Data Group 1979), e.g., noninsulin-dependent diabetes, maturity onset diabetes in the young (MODY), and ...
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Molecular Mimicry of Carbohydrates by Peptides
Australian Journal of Chemistry, 2002The use of carbohydrates as drugs and vaccines has several limitations. Molecular mimics of carbohydrates provide an alternative source of compounds to target pathways involving protein-carbohydrate interactions. In recent years, immunological studies have demonstrated the ability of certain peptides to act as molecular mimics of carbohydrates, in that
Margaret A. Johnson, B.M. Pinto
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Molecular Mimicry and Autoimmunity
1986There are several mechanisms by which viruses may initiate autoimmunity event. For example, a virus could interact directly with cells of the immune system and alter normal immune regulation. Inability to respond to self antigens is maintained, primarily in part, by tolerizing T cells (1). Such tolerant T cells cannot provide the appropriate signal for
Robert S. Fujinami +1 more
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Molecular mechanisms of floral mimicry in orchids
Trends in Plant Science, 2008Deceptive plants do not produce floral rewards, but attract pollinators by mimicking signals of other organisms, such as food plants or female insects. Such floral mimicry is particularly common in orchids, in which flower morphology, coloration and odour play key roles in deceiving pollinators.
Schlüter, P M, Schiestl, F P
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2014
The term molecular mimicry was originally used by Raymon T. Damian to describe the sharing of antigenic structures, such as proteins, lipids, or carbohydrates, by parasite and host. In terms of autoimmune-like reactions, Damian referred to a work by Rowley and Jenkin published in 1962.
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The term molecular mimicry was originally used by Raymon T. Damian to describe the sharing of antigenic structures, such as proteins, lipids, or carbohydrates, by parasite and host. In terms of autoimmune-like reactions, Damian referred to a work by Rowley and Jenkin published in 1962.
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Molecular Mimicry in Protein Synthesis?
Science, 1995A Research Article in this issue of Science by P. Nissen et al . ( p. 1464 ) reports the crystal structure of elongation factor Tu (EF-Tu) complexed with tRNA and GTP. In his Perspective, P.
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