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Molecular mimicry is one of the evolutionary strategies that parasites use to manipulate the host metabolism and perform an effective infection. This phenomenon has been observed in several animal and plant pathosystems.
Vinicio Armijos-Jaramillo+3 more
doaj +1 more source
Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry
Understanding broadly neutralizing sarbecovirus antibody responses is key to developing countermeasures effective against SARS-CoV-2 variants and future spillovers of other sarbecoviruses.
Young-Jun Park+25 more
semanticscholar +1 more source
Genome-wide identification of molecular mimicry candidates in parasites. [PDF]
Among the many strategies employed by parasites for immune evasion and host manipulation, one of the most fascinating is molecular mimicry. With genome sequences available for host and parasite, mimicry of linear amino acid epitopes can be investigated ...
Philipp Ludin+2 more
doaj +1 more source
The molecular mimicry and COVID-19
A significant part of the complications of COVID-19 and manifestations of post-COVID syndrome is associated with autoimmune reactions caused by SARS-CoV-2.
Veronika Zorina
doaj +1 more source
Molecular Mimicry and Autoimmunity [PDF]
Autoimmune disease is the consequence of an immune response against self-antigens that results in the damage and eventual dysfunction of target organs. Although the triggering event in most autoimmune diseases is unknown, an infectious cause has long been postulated to explain the development of autoimmunity. Molecular mimicry is one mechanism by which
Lori Albert, Robert D. Inman
openaire +5 more sources
Molecular mimicry between SARS‐CoV‐2 and the female reproductive system
Oogenesis, the process of egg production by the ovary, involves a complex differentiation program leading to the production of functional oocytes. This process comprises a sequential pathway of steps that are finely regulated.
A. Dotan+4 more
semanticscholar +1 more source
Conformational Plasticity of HLA-B27 Molecules Correlates Inversely With Efficiency of Negative T Cell Selection [PDF]
The development of autoimmune disorders is incompletely understood. Inefficient thymic T cell selection against self-peptides presented by major histocompatibility antigens (HLA in humans) may contribute to the emergence of auto-reactive effector cells ...
Loll, Bernhard+3 more
core +1 more source
From Anti-SARS-CoV-2 Immune Response to the Cytokine Storm via Molecular Mimicry
The aim of this study was to investigate the role of molecular mimicry in the cytokine storms associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Human proteins endowed with anti-inflammatory activity were assembled and analyzed
D. Kanduc
semanticscholar +1 more source
Approximately 30% of individuals with severe SARS-CoV-2 infections also develop neurological and psychiatric complaints. In rare cases, the occurrence of autoimmune encephalitis has been reported after SARS-CoV-2 infection.
V. Vasilevska+5 more
semanticscholar +1 more source
The ethiopathology of the diseasome induced by the SARSCoV-2 infection in the human host [1] is under intensive investigation. A likely mechanism is that the multitude of the diseases encompassed within COVID-19 derives frommolecular mimicry phenomena ...
D. Kanduc, Y. Shoenfeld
semanticscholar +1 more source