Results 31 to 40 of about 2,281 (156)

Hepatitis C Virus and Molecular Mimicry

Pathogens
This review delves into the interactions between hepatitis C virus (HCV) and the host immune system, shedding light on how by using the mechanism of molecular mimicry, the virus strategically evades the immune system, resulting in a cascade of diverse ...
Lynette Goh, Nanda Kerkar
doaj   +1 more source

Mining Autoimmune-Disorder-Linked Molecular-Mimicry Candidates in Clostridioides difficile and Prospects of Mimic-Based Vaccine Design: An In Silico Approach

Microorganisms, 2023
Molecular mimicry, a phenomenon in which microbial or environmental antigens resemble host antigens, has been proposed as a potential trigger for autoimmune responses.
Saleh Alshamrani, Mutaib M. Mashraqi, Ahmad Alzamami, Norah A. Alturki, Hassan H. Almasoudi, Mohammed Abdulrahman Alshahrani, Zarrin Basharat   +6 more
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Müllerian mimicry as a result of codivergence between velvet ants and spider wasps.

PLoS ONE, 2014
Recent studies have delineated a large Nearctic Müllerian mimicry complex in Dasymutilla velvet ants. Psorthaspis spider wasps live in areas where this mimicry complex is found and are phenotypically similar to Dasymutilla.
Juanita Rodriguez, James P Pitts, Carol D von Dohlen, Joseph S Wilson   +3 more
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Molecular mimicry as a mechanism of viral immune evasion and autoimmunity

Nature Communications
Mimicry of host protein structures, or ‘molecular mimicry’, is a common mechanism employed by viruses to evade the host’s immune system. Short linear amino acid (AA) molecular mimics can elicit cross-reactive antibodies and T cells from the host, but the
Cole Maguire, Chumeng Wang, Akshara Ramasamy, Cara Fonken, Brinkley Morse, Nathan Lopez, Dennis Wylie, Esther Melamed   +7 more
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The balance between deception and adaptation: vasculogenic mimicry as a tumor survival strategy

Успехи молекулярной онкологии
Vasculogenic mimicry is a unique process through which tumor cells imitate normal vascular endothelial cells to secure access to the blood flow. In this review, we consider molecular mechanisms underlying this phenomenon and its importance in the context
E. A. Prosekina, V. A. Shapkina, A. E. Karpov, E. Yu. Fedorutseva, A. S. Artemyeva   +4 more
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Microbiome, Parkinson’s Disease and Molecular Mimicry

Cells, 2019
Parkinson’s Disease (PD) is typically classified as a neurodegenerative disease affecting the motor system. Recent evidence, however, has uncovered the presence of Lewy bodies in locations outside the CNS, in direct contact with the external ...
Fabiana Miraglia, Emanuela Colla
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Epitopedia: identifying molecular mimicry between pathogens and known immune epitopes

ImmunoInformatics, 2023
Upon infection, foreign antigenic proteins stimulate the host's immune system to produce antibodies targeting the pathogen. These antibodies bind to regions on the antigen called epitopes.
Christian A Balbin, Janelle Nunez-Castilla, Vitalii Stebliankin, Prabin Baral, Masrur Sobhan, Trevor Cickovski, Ananda Mohan Mondal, Giri Narasimhan, Prem Chapagain, Kalai Mathee, Jessica Siltberg-Liberles   +10 more
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Molecular Mimicry Mapping in Streptococcus pneumoniae: Cues for Autoimmune Disorders and Implications for Immune Defense Activation

Pathogens, 2023
Streptococcus pneumoniae contributes to a range of infections, including meningitis, pneumonia, otitis media, and sepsis. Infections by this bacterium have been associated with the phenomenon of molecular mimicry, which, in turn, may contribute to the ...
Mutaib M. Mashraqi, Ahmad Alzamami, Norah A. Alturki, Saleh Alshamrani, Mousa M. Alshahrani, Hassan H. Almasoudi, Zarrin Basharat   +6 more
doaj   +1 more source

Phosphoregulation accommodates Type III secretion and assembly of a tether of ER-Chlamydia inclusion membrane contact sites

eLife, 2022
Membrane contact sites (MCS) are crucial for nonvesicular trafficking-based interorganelle communication. Endoplasmic reticulum (ER)–organelle tethering occurs in part through the interaction of the ER resident protein VAP with FFAT motif-containing ...
Rachel J Ende, Rebecca L Murray, Samantha K D'Spain, Isabelle Coppens, Isabelle Derré   +4 more
doaj   +1 more source

The role of molecular mimicry in the etiology of Guillain Barré Syndrome [PDF]

Makedonsko Farmacevtski Bilten, 2011
Molecular mimicry between host tissue structures and microbial components has been proposed as the pathogenic mechanism for triggeringof autoimmune diseases by preceding infection.
Aleksandra Grozdanova, Slobodan Apostolski, Ljubica Suturkova   +2 more
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