Results 31 to 40 of about 3,812,700 (365)

Molecular mimicry and autoimmunity.

Journal of Autoimmunity, 2018
Molecular mimicry is one of the leading mechanisms by which infectious or chemical agents may induce autoimmunity. It occurs when similarities between foreign and self-peptides favor an activation of autoreactive T or B cells by a foreign-derived antigen in a susceptible individual.
M. Rojas, Paula Restrepo-Jiménez, D. Monsalve, Y. Pacheco, Y. Acosta-Ampudia, C. Ramírez-Santana, P. Leung, A. Ansari, M. Gershwin, J. Anaya   +9 more
semanticscholar   +4 more sources

Molecular Mimicry in Multiple Sclerosis

, 2007
One of the most common demyelinating central nervous system (CNS) diseases in humans is multiple sclerosis (MS). The disease can be very debilitating with vision loss, motor and sensory disturbances, and cognitive impairment. The clinical course may present as a relapsing-remitting disease course, a progressive disease course, or a combination thereof.
Jane E. Libbey, Lori McCoy, Robert S. Fujinami   +2 more
openalex   +4 more sources

Conformational Plasticity of HLA-B27 Molecules Correlates Inversely With Efficiency of Negative T Cell Selection [PDF]

, 2020
The development of autoimmune disorders is incompletely understood. Inefficient thymic T cell selection against self-peptides presented by major histocompatibility antigens (HLA in humans) may contribute to the emergence of auto-reactive effector cells ...
Loll, Bernhard, Rückert, Christine, Uchanska-Ziegler, Barbara, Ziegler, Andreas   +3 more
core   +1 more source

Molecular Mimicry and Autoimmunity [PDF]

New England Journal of Medicine, 1999
Autoimmune disease is the consequence of an immune response against self-antigens that results in the damage and eventual dysfunction of target organs. Although the triggering event in most autoimmune diseases is unknown, an infectious cause has long been postulated to explain the development of autoimmunity. Molecular mimicry is one mechanism by which
Lori Albert, Robert D. Inman
openaire   +5 more sources

Genome-wide identification of molecular mimicry candidates in parasites. [PDF]

PLoS ONE, 2011
Among the many strategies employed by parasites for immune evasion and host manipulation, one of the most fascinating is molecular mimicry. With genome sequences available for host and parasite, mimicry of linear amino acid epitopes can be investigated ...
Philipp Ludin, Daniel Nilsson, Pascal Mäser   +2 more
doaj   +1 more source

Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry

bioRxiv, 2021
Understanding broadly neutralizing sarbecovirus antibody responses is key to developing countermeasures effective against SARS-CoV-2 variants and future spillovers of other sarbecoviruses.
Young-Jun Park, A. De Marco, Tyler N. Starr, Zhuoming Liu, D. Pinto, A. Walls, F. Zatta, Samantha K. Zepeda, John E. Bowen, Kaitlin S Sprouse, Anshu Joshi, M. Giurdanella, B. Guarino, Julia Noack, R. Abdelnabi, S. Foo, Florian A. Lempp, F. Benigni, G. Snell, J. Neyts, S. Whelan, H. Virgin, J. Bloom, D. Corti, M. Pizzuto, D. Veesler   +25 more
semanticscholar   +1 more source

Genes Suggest Ancestral Colour Polymorphisms Are Shared across Morphologically Cryptic Species in Arctic Bumblebees [PDF]

, 2015
email Suzanne orcd idCopyright: © 2015 Williams et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
A Bertsch, A Bertsch, A Cardoso, A Estoup, A Løken, A Papadopoulou, A Pekkarinen, AJ Drummond, Alexandr M. Byvaltsev, AS Skorikov, AS Skorikov, B Pittioni, B Tkalcu, B Tkalcu, BC Schlick-Steiner, BG Svensson, BG Svensson, Björn Cederberg, CD Michener, Claus Rasmussen, Cory S. Sheffield, D Baum, DR Maddison, DV Panfilov, E Krüger, EO Wilson, F Leliaert, Frode Ødegaard, G Talavera, GF Barrowclough, H Friese, H Pringle, H Song, HE Milliron, HM Hines, HM Hines, IC Barro, J Brigham-Grette, J Mallet, J Pons, J-J Zhang, J-X Huang, JC Carolan, Jiaxing Huang, JO Gjershaug, JP Huelsenbeck, JP Strange, K de Queiroz, K Tamura, KJ Gaston, KN Magnacca, KW Richards, KW von Dalla Torre, Leif L. Richardson, M Terzo, MA Duennes, Mikhail V. Berezin, MK Fujita, MP Cristiano, MR Kronforst, MT Monaghan, MT Monaghan, NM Reid, O Radoszkowski, O Vogt, O Vogt, OW Richards, OW Richards, P Pamilo, P Rasmont, P Rasmont, P Rasmont, Paul H. Williams, PDN Hebert, PDN Hebert, PH Williams, PH Williams, PH Williams, PH Williams, PH Williams, PH Williams, PH Williams, PH Williams, PH Williams, PH Williams, R Neumeyer, R Rougerie, RC Plowright, RM Zink, RM Zink, S Ratnasingham, SA Cameron, SA Elias, ST Williams, Suzanne T. Williams, SV Edwards, T De Meulemeester, T Fujisawa, T Lecocq, T Lecocq, T Lecocq, T Lecocq, WF Reinig, WF Reinig, WF Reinig, WP Maddison, Z Rapti, Zuogang Peng   +107 more
core   +15 more sources

The molecular mimicry and COVID-19

Инфекция и иммунитет, 2023
A significant part of the complications of COVID-19 and manifestations of post-COVID syndrome is associated with autoimmune reactions caused by SARS-CoV-2.
Veronika Zorina
doaj   +1 more source

Molecular mimicry between SARS‐CoV‐2 and the female reproductive system

American Journal of Reproductive Immunology, 2021
Oogenesis, the process of egg production by the ovary, involves a complex differentiation program leading to the production of functional oocytes. This process comprises a sequential pathway of steps that are finely regulated.
A. Dotan, D. Kanduc, S. Muller, A. Makatsariya, Y. Shoenfeld   +4 more
semanticscholar   +1 more source

Infectious diseases and autoimmunity [PDF]

, 2011
Introduction: Autoimmunity occurs when the immune system recognizes and attacks host tissue. In addition to genetic factors, environmental triggers (in particular viruses, bacteria and other infectious pathogens) are thought to play a major role in the ...
Deidda, Silvia, Delitala, Giuseppe, Delogu, Lucia Gemma, Manetti, Roberto   +3 more
core   +1 more source