Results 71 to 80 of about 1,213,798 (272)

The structure of the agrochemical fungicidal 4-Chloro-3-(3,5-dichloropheny)-1H-pyrazole, RPA 406194 and related compounds [PDF]

, 2003
The difficulties to obtain convenient monocrystals of the important fungicide RPA 406194 have been overcome by a combination of solid state 13C NMR, X-ray powder diffraction and molecular modeling.
Abboud, Aguilar-Parrilla, Bennema, Berkovitch-Yellin, Burton, Cativiela, Cativiela, Claramunt, Dunitz, Elguero, Elguero, Eliel, Foces-Foces, Grimbergen, Harris, Hartman, Hartman, Hartman, Hartman, Jean Paul Canselier, Jean-Pierre Vors, José Elguero, Lin, Lin, Lommerse, López, Marı́a Luisa Jimeno, Minkin, Nadine Gabas, Nadine Jagerovic, Olivieri, Stothers, Vincent Gerbaud, Weissbuch, Winn, Winn   +35 more
core   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Computational screening of the effects of mutations on protein-protein off-rates and dissociation mechanisms by τRAMD

Communications Biology
The dissociation rate, or its reciprocal, the residence time (τ), is a crucial parameter for understanding the duration and biological impact of biomolecular interactions.
Giulia D’Arrigo, Daria B. Kokh, Ariane Nunes-Alves, Rebecca C. Wade   +3 more
doaj   +1 more source

A Master equation approach to modeling an artificial protein motor

, 2010
Linear bio-molecular motors move unidirectionally along a track by coordinating several different processes, such as fuel (ATP) capture, hydrolysis, conformational changes, binding and unbinding from a track, and center-of-mass diffusion.
Alberts, Allen, Astumian, Astumian, Astumian, Astumian, Balzani, Bath, Borden, Bromley, Bustamante, Carey, Craig, Eaton, Feringa, Finucane, Geertsema, Gerhard A. Blab, Greenleaf, Heiner Linke, Howard, Kay, Klok, Kottas, Magnasco, Nathan J. Kuwada, Parsons, Phillips, Schaad, Silvi, Stockley, van Delden, Vilfan, Vilfan, Wang, Yurke   +35 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Temperature stability of intersubband transitions in AlN/GaN quantum wells

, 2010
Temperature dependence of intersubband transitions in AlN/GaN multiple quantum wells grown with molecular beam epitaxy is investigated both by absorption studies at different temperatures and modeling of conduction-band electrons.
Andersson, Thorvald G., Berland, Kristian, Farivar, Rashid, Hyldgaard, Per, Larsson, Anders, Stattin, Martin, Sultan, D. M. S., Wang, Shu Min   +7 more
core   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Modeling Molecular Hydrogen and Star Formation in Cosmological Simulations

, 2009
We describe a phenomenological model for molecular hydrogen formation suited for applications in galaxy formation simulations, which includes on-equilibrium formation of molecular hydrogen on dust and approximate treatment of both its self-shielding and ...
Andrey V. Kravtsov, Bigiel, Blitz, Blitz, Brooks, Browning, Cazaux, Ceverino, Chen, Croft, Das, Downes, Galli, Gibson, Gillmon, Glover, Glover, Goldsmith, Heyer, Kennicutt, Kennicutt, Konstantinos Tassis, Kravtsov, Kravtsov, Kravtsov, Kravtsov, Krumholz, Krumholz, Krumholz, Leroy, Leroy, Matthews, Mayer, Nickolay Y. Gnedin, Ostriker, Padoan, Pelupessy, Razoumov, Robertson, Schaye, Tasker, Tassis, Tumlinson, Wolfe, Wolfire, Wolfire, Wong, Wyder   +47 more
core   +1 more source