Results 111 to 120 of about 11,611,859 (368)
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
Endogenous molecular network reveals two mechanisms of heterogeneity within gastric cancer
OncoTarget, 2015 Intratumor heterogeneity is a common phenomenon and impedes cancer therapy and research. Gastric cancer (GC) cells have generally been classified into two heterogeneous cellular phenotypes, the gastric and intestinal types, yet the mechanisms of ...
Site Li +4 more
semanticscholar +1 more source
Molecular Beamforming for Actuation in Molecular Communication Networks
IEEE Transactions on NanoBioscienceThe actuation accuracy of sensing tasks performed by molecular communication (MC) schemes is a very important metric. Reducing the effect of sensors fallibility can be achieved by improvements and advancements in the sensor and communication networks design.
Joana Angjo +4 more
openaire +3 more sources
Molecular motors and stochastic networks [PDF]
Banach Center Publications, 2008 Molecular motors are nanoor colloidal machines that keep the living cell in a highly ordered, stationary state far from equilibrium. This self-organized order is sustained by the energy transduction of the motors, which couple exergonic or ‘downhill’ processes to endergonic or ‘uphill’ processes.
Lipowsky, R., Liepelt, S.
openaire +3 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Frontiers in Endocrinology, 2016 Pituitary adenoma is a common disease occurring in pituitary that is a central regulatory organ in endocrine system and is clinically categorized as functional and non-functional pituitary adenomas (FPA and NFPA) (1–4).
X. Zhan, Ying Long
semanticscholar +1 more source
Regulatory elements in molecular networks
WIREs Systems Biology and Medicine, 2017 Regulatory elements determine the connectivity of molecular networks and mediate a variety of regulatory processes ranging from DNA looping to transcriptional, posttranscriptional, and posttranslational regulation. This review highlights our current understanding of the different types of regulatory elements found in molecular networks with a focus on ...
Ashley S. Doane, Olivier Elemento
openaire +4 more sources
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
Molecular mode-coupling theory for supercooled liquids: Application to water
, 1999 We present mode-coupling equations for the description of the slow dynamics observed in supercooled molecular liquids close to the glass transition.
A. Latz +26 more
core +1 more source
Ecology and Evolution, 2020 Ecological release from herbivory due to chemical novelty is commonly predicted to facilitate biological invasions by plants, but has not been tested on a community scale.
Brian E. Sedio +5 more
doaj +1 more source