Molecular pharming to support human life on the moon, mars, and beyond [PDF]
Space missions have always assumed that the risk of spacecraft malfunction far outweighs the risk of human system failure. This assumption breaks down for longer duration exploration missions and exposes vulnerabilities in space medical system. Space agencies can no longer buy down the majority of human system risk through the crew member selection ...
Matthew J. McNulty +10 more
openaire +8 more sources
Blood pharming: exploring the progress and hurdles in producing in-vitro red blood cells for therapeutic applications [PDF]
Transfusion Medicine is facing mounting challenges, including but not limited to donor availability, blood supply shortages, and transfusion-associated complications, such as immunogenicity and transmission of viral infections.
Hammad Hassan, Sheerien Rajput
doaj +3 more sources
Molecular pharming — VLPs made in plants [PDF]
Plant-based expression offers a safe, inexpensive and potentially limitless way to produce therapeutics in a quick and flexible manner. Plants require only simple inorganic nutrients, water, carbon dioxide and sunlight for efficient growth. Virus-like particles (VLPs) are convincing look-alikes of viruses but without carrying infectious genomic ...
Marsian, Johanna, Lomonossoff, George P
openaire +3 more sources
Assessment of bacterial proteome remodeling under virulence-inducing conditions for molecular pharming applications [PDF]
Nicholas Prudhomme +1 more
exaly +2 more sources
The productivity of major field crops is highly compromised due to weed infestation. Inefficient weed management practices and undue and excessive use of chemical herbicides have drastically contaminated the environment and human health, in addition to ...
Sobia Anwar +5 more
doaj +1 more source
Multi-Omics Identification of Yield Limiting Factors in Molecular Pharming [PDF]
Biologics, including protein-based drugs, are among the fastest growing categories of therapeutics under development today. While most biologics are made using mammalian cell systems, plant-based production systems provide a cost-effective approach to ...
Prudhomme, Nicholas
core +2 more sources
Combating Human Viral Diseases: Will Plant-Based Vaccines Be the Answer?
Molecular pharming or the technology of application of plants and plant cell culture to manufacture high-value recombinant proteins has progressed a long way over the last three decades.
Srividhya Venkataraman +3 more
doaj +1 more source
Plant-based vaccines: Potentiality against severe acute respiratory syndrome coronavirus 2
The pandemic of novel coronavirus disease-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has stimulated scientists from different backgrounds to gear up on developing vaccines against the virus.
Pramita Sharma +3 more
doaj +1 more source
Rabies virus glycoprotein produced in Nicotiana benthamiana is an immunogenic antigen in mice
Rabies remains an infectious disease among humans and animals, and requires the development of an effective vaccine essential to prevent rabies. Advances in molecular biology and biotechnology have led to the development and improvement of many rabies ...
Youngmin Park +10 more
doaj +1 more source
Current status and perspectives of the molecular farming landscape [PDF]
Art. 20180330, 23 S.This chapter provides an overview of the current state of molecular farming, which is characterized by the development of sizeable production capacities, a greater focus on downstream processing and scale-up, and the targeting of ...
Stöger, E. +3 more
core +1 more source

