Recent Progress on Vaccines Produced in Transgenic Plants
Vaccines, 2022 The development of vaccines from plants has been going on for over two decades now. Vaccine production in plants requires time and a lot of effort. Despite global efforts in plant-made vaccine development, there are still challenges that hinder the ...
Goabaone Gaobotse +5 more
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Potential of chloroplast genome in plant breeding
Czech Journal of Genetics and Plant Breeding, 2010 Chloroplast engineering (or chloroplast transformation technology, CTT) is a strategy consisting of inserting a transgene into the chloroplast genome of a plant instead of its nuclear genome.
Jana Řepková
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Plant molecular pharming 2012 and beyond [PDF]
Plant Cell Reports, 2012 It is with significant pride that we bring to you this special issue on Plant Molecular Pharming. We prefer the term ‘‘Pharming’’ rather than ‘‘Farming’’ because all of the proteins and secondary products are destined to be introduced into the human health marketplace.
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An in silico overview on the usefulness of tags and linkers in plant molecular pharming [PDF]
, 2014 Plant molecular pharming is a promising concept based on the large-scale production of recombinant proteins encompassing antibodies, vaccines and enzymes for human or veterinary uses and treatments.
Trémouillaux-Guiller, Jocelyne +4 more
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Protein modifications in the plant secretory pathway: current status and practical implications in molecular pharming. [PDF]
, 2005 International audiencePlants have become, over the last ten years, a suitable alternative to microbial and animal cell factories for the production of clinically-useful, therapeutic proteins.
Michaud, Dominique +4 more
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Enhancement of heterologous gene expression in Flammulina velutipes using polycistronic vectors containing a viral 2A cleavage sequence. [PDF]
PLoS ONE, 2013 Agrobacterium tumefaciens-mediated transformation for edible mushrooms has been previously established. However, the enhancement of heterologous protein production and the expression of multi-target genes remains a challenge.
Yu-Ju Lin +2 more
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Antibody degradation in tobacco plants: a predominantly apoplastic process. [PDF]
, 2011 BACKGROUND: Interest in using plants for production of recombinant proteins such as monoclonal antibodies is growing, but proteolytic degradation, leading to a loss of functionality and complications in downstream purification, is still a serious problem.
Hehle, VK +14 more
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Quantitative proteomic profiling of shake flask versus bioreactor growth reveals distinct responses of Agrobacterium tumefaciens for preparation in molecular pharming [PDF]
, 2020 The preparation of Agrobacterium tumefaciens cultures with strains encoding proteins intended for therapeutic or industrial purposes is an important activity prior to treatment of plants for transient expression of valuable protein products.
McLean, Michael D. +7 more
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Frontiers in Plant ScienceAs an important cash crop, tobacco (Nicotiana tabacum L.) is grown to harvest leaves which are cured at elevated temperature before sale. The quality of cured leaves impacts the economic return of growers.
Tao Liu +11 more
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Functionalizing silica sol–gel with entrapped plant virus-based immunosorbent nanoparticles
Journal of Nanobiotechnology, 2022 Advancements in understanding and engineering of virus-based nanomaterials (VBNs) for biomedical applications motivate a need to explore the interfaces between VBNs and other biomedically-relevant chemistries and materials.
Matthew J. McNulty +6 more
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