Results 251 to 260 of about 4,368,802 (298)

The Molecular Physiology of Citrate

Nature, 1965
Publisher Summary This chapter discusses the molecular physiology of citrate. It discusses the properties of the enzymes that metabolized citrate. High concentrations of citrate are found in bone and other biominerals, in prostate and seminal fluid as a fermentation product of molds, and in citrus fruits.
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Molecular characteristics and physiology of microsporidia

Microbes and Infection, 2001
A survey of the molecular features of microsporidia is presented which attempts to comment on unresolved questions concerning the physiology of these amitochondrial intracellular parasites. Various transports of host-derived molecules can be predicted and trehalose appears as a potential reserve of glucose for energy metabolism.
G, Méténier, C P, Vivarès
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Molecular Physiology of the WNK Kinases

Annual Review of Physiology, 2008
Mutations in the serine-threonine kinases WNK1 and WNK4 cause a Mendelian disease featuring hypertension and hyperkalemia. In vitro and in vivo studies have revealed that these proteins are molecular switches that have discrete functional states that impart different effects on downstream ion channels, transporters, and the paracellular pathway. These
Kristopher T, Kahle, Aaron M, Ring, Richard P, Lifton   +2 more
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Molecular mechanism of physiological fibrinolysis

Nature, 1978
THE proteolytic enzyme system in blood that is predominantly responsible for removal of fibrin deposits, is called the fibrinolytic system. This system consists of three main components: the proenzyme plasminogen, which can be activated by limited proteolysis to the proteolytic enzyme plasmin; plasminogen activators, the most important of which ...
B, Wiman, D, Collen
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Molecular Physiology of P2X Receptors

Physiological Reviews, 2002
P2X receptors are membrane ion channels that open in response to the binding of extracellular ATP. Seven genes in vertebrates encode P2X receptor subunits, which are 40–50% identical in amino acid sequence. Each subunit has two transmembrane domains, separated by an extracellular domain (∼280 amino acids). Channels form as multimers of several subunits.
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Omics and the molecular exercise physiology

2020
Exercise is a well-known non-pharmacologic agent used to prevent and treat a wide range of pathologic conditions such as metabolic and cardiovascular disease. In this sense, the classic field of exercise physiology has determined the main theoretical and practical bases of physiologic adaptations in response to exercise.
Cpc, Gomes, Jeeser Alves, Almeida, Octávio Luiz, Franco, Bernardo, Petriz   +3 more
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Physiologic and molecular biology of erythropoietin

Medical Oncology and Tumor Pharmacotherapy, 1986
The gene for erythropoietin, the first growth and differentiation factor to be identified, has now been cloned and a recombinant erythropoietin is ready for clinical trials. This molecular achievement has also led to the identification of its mRNA in liver and especially in kidney tissue and here in the extra glomerular fraction.
A J, Erslev, J, Caro
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The molecular physiology of taste transduction

Current Opinion in Neurobiology, 2000
Taste receptor cells use a variety of mechanisms to transduce chemical information into cellular signals. Seven-transmembrane-helix receptors initiate signaling cascades by coupling to G proteins, effector enzymes, second messengers and ion channels. Apical ion channels pass ions, leading to depolarizing and/or hyperpolarizing responses.
T A, Gilbertson, S, Damak, R F, Margolskee   +2 more
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Molecular physiology of aquaporins in plants

2002
In plants, membrane channels of the major intrinsic protein (MIP) super-family exhibit a high diversity with, for instance, 35 homologues in the model species Arabidopsis thaliana. As has been found in other organisms, plant MIPs function as membrane channels permeable to water (aquaporins) and in some cases to small nonelectrolytes.
Maurel, Christophe, Javot, Héléne, Lauvergeat, V., Lauvergeat, Virginie, Gerbeau, Patricia, Tournaire, Colette, Santoni, Veronique, Heyes, Julian   +7 more
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Molecular Physiology of Cardiac Repolarization

Physiological Reviews, 2005
The heart is a rhythmic electromechanical pump, the functioning of which depends on action potential generation and propagation, followed by relaxation and a period of refractoriness until the next impulse is generated. Myocardial action potentials reflect the sequential activation and inactivation of inward (Na+and Ca2+) and outward (K+) current ...
Jeanne M, Nerbonne, Robert S, Kass
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