Results 251 to 260 of about 1,247,695 (303)
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Molecular mechanism of physiological fibrinolysis
Nature, 1978THE proteolytic enzyme system in blood that is predominantly responsible for removal of fibrin deposits, is called the fibrinolytic system. This system consists of three main components: the proenzyme plasminogen, which can be activated by limited proteolysis to the proteolytic enzyme plasmin; plasminogen activators, the most important of which ...
B, Wiman, D, Collen
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Molecular Physiology of Cardiac Repolarization
Physiological Reviews, 2005The heart is a rhythmic electromechanical pump, the functioning of which depends on action potential generation and propagation, followed by relaxation and a period of refractoriness until the next impulse is generated. Myocardial action potentials reflect the sequential activation and inactivation of inward (Na+and Ca2+) and outward (K+) current ...
Jeanne M, Nerbonne, Robert S, Kass
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Molecular Physiology of Urate Transport
Physiology, 2005Humans excrete uric acid as the final breakdown product of unwanted purine nucleotides. Urate scavenges potential harmful radicals in our body. However, in conjunction with genetic or environmental (especially dietary) factors, urate may cause gout, nephrolitiasis, hypertension, and vascular disease.
Matthias A, Hediger +3 more
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Molecular physiology of cardiac regeneration
Annals of the New York Academy of Sciences, 2010Heart disease is the leading cause of death in the industrialized world. This is partially attributed to the inability of cardiomyocytes to divide in a significant manner, and therefore the heart responds to injury through scar formation. One of the challenges of modern medicine is to develop novel therapeutic strategies to facilitate regeneration of ...
Paola, Bolli, Hina W, Chaudhry
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Molecular Physiology of P2X Receptors
Physiological Reviews, 2002P2X receptors are membrane ion channels that open in response to the binding of extracellular ATP. Seven genes in vertebrates encode P2X receptor subunits, which are 40–50% identical in amino acid sequence. Each subunit has two transmembrane domains, separated by an extracellular domain (∼280 amino acids). Channels form as multimers of several subunits.
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Molecular Physiology of Glucose Transporters
Diabetes Care, 1990Molecular cloning of cDNA encoding the human erythrocyte facilitated-diffusion glucose transporter (GT) has elucidated its structure and has permitted a careful study of its tissue distribution and of its involvement in processes such as insulin-stimulated glucose uptake by adipose cells or transformation-induced increase in glucose metabolism.
B, Thorens, M J, Charron, H F, Lodish
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Molecular sensory physiology ofEuglena
Die Naturwissenschaften, 1976After a short description of the motile physiology of Euglena gracilis the responses to light stimulation are analyzed and a new nomenclature is proposed concerning flagellar motility variations. A discussion follows about the characteristics of the photoreceptive system of Euglena and about the flavinic nature of its phototactic pigments.
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2017
Abstract Molecular exercise physiology is the study of exercise physiology using molecular biology methods. The development of differentiated cell types is regulated by transcription factors like the muscle-making MyoD that specifies cell type, while others regulate the development of muscle, tendons, and bones.
Henning Wackerhage +2 more
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Abstract Molecular exercise physiology is the study of exercise physiology using molecular biology methods. The development of differentiated cell types is regulated by transcription factors like the muscle-making MyoD that specifies cell type, while others regulate the development of muscle, tendons, and bones.
Henning Wackerhage +2 more
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The Molecular Physiology of Citrate
Nature, 1965Publisher Summary This chapter discusses the molecular physiology of citrate. It discusses the properties of the enzymes that metabolized citrate. High concentrations of citrate are found in bone and other biominerals, in prostate and seminal fluid as a fermentation product of molds, and in citrus fruits.
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Molecular physiology of anion channels
Current Opinion in Cell Biology, 1994Anion channels have diverse functions, ranging from regulation of cell volume to transepithelial transport and control of excitability. Three well established structural classes of plasma membrane chloride channels now exist: the ligand-gated chloride channels, the cAMP-stimulated cystic fibrosis transmembrane conductance regulator channel, and the ...
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