O-GlcNAcylation: cellular physiology and therapeutic target for human diseases. [PDF]
MedComm (2020), 2023 O‐linked‐β‐N‐acetylglucosamine (O‐GlcNAcylation) is a distinctive posttranslational protein modification involving the coordinated action of O‐GlcNAc transferase and O‐GlcNAcase, primarily targeting serine or threonine residues in various proteins.
Ye L +6 more
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Cellular Physiology and Pathophysiology of EAAT Anion Channels. [PDF]
Front Cell Neurosci, 2021 Excitatory amino acid transporters (EAATs) optimize the temporal resolution and energy demand of mammalian excitatory synapses by quickly removing glutamate from the synaptic cleft into surrounding neuronal and glial cells and ensuring low resting ...
Kovermann P +3 more
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Long non-coding RNAs: novel regulators of cellular physiology and function. [PDF]
Pflugers Arch, 2022 Long non-coding RNAs were once considered as “junk” RNA produced by aberrant DNA transcription. They are now understood to play central roles in diverse cellular processes from proliferation and migration to differentiation, senescence and DNA damage ...
Oo JA, Brandes RP, Leisegang MS.
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Roles and Functions of ROS and RNS in Cellular Physiology and Pathology. [PDF]
Cells, 2020 Our common knowledge on oxidative stress has evolved substantially over the years, being focused mostly on the fundamental chemical reactions and the most relevant chemical species involved in human pathophysiology of oxidative stress-associated diseases.
Zarkovic N.
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The Emerging and Diverse Roles of Bis(monoacylglycero) Phosphate Lipids in Cellular Physiology and Disease. [PDF]
Int J Mol Sci, 2020 Although understudied relative to many phospholipids, accumulating evidence suggests that bis(monoacylglycero)phosphate (BMP) is an important class of regulatory lipid that plays key roles in lysosomal integrity and function.
Showalter MR +5 more
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Role of Endoplasmic Reticulum Stress Sensor IRE1α in Cellular Physiology, Calcium, ROS Signaling, and Metaflammation. [PDF]
Cells, 2020 Inositol-requiring transmembrane kinase endoribonuclease-1α (IRE1α) is the most prominent and evolutionarily conserved unfolded protein response (UPR) signal transducer during endoplasmic reticulum functional upset (ER stress).
Riaz TA +5 more
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Regulator of G protein signaling 10: Structure, expression and functions in cellular physiology and diseases. [PDF]
Cell Signal, 2020 Regulator of G protein signaling 10 (RGS10) belongs to the superfamily of RGS proteins, defined by the presence of a conserved RGS domain that canonically binds and deactivates heterotrimeric G-proteins.
Almutairi F, Lee JK, Rada B.
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Mitochondrial Gene Expression and Beyond-Novel Aspects of Cellular Physiology. [PDF]
Cells, 2019 Mitochondria are peculiar organelles whose proper function depends on the crosstalk between two genomes, mitochondrial and nuclear. The human mitochondrial genome (mtDNA) encodes only 13 proteins; nevertheless, its proper expression is essential for ...
Kotrys AV, Szczesny RJ.
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Linkage between Carbon Metabolism, Redox Status and Cellular Physiology in the Yeast Saccharomyces cerevisiae Devoid of SOD1 or SOD2 Gene. [PDF]
Genes (Basel), 2020 Saccharomyces cerevisiae yeast cells may generate energy both by fermentation and aerobic respiration, which are dependent on the type and availability of carbon sources.
Maslanka R +2 more
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Progress in automating patch clamp cellular physiology. [PDF]
Brain Neurosci Adv, 2018 Patch clamp electrophysiology has transformed research in the life sciences over the last few decades. Since their inception, automatic patch clamp platforms have evolved considerably, demonstrating the capability to address both voltage- and ligand ...
Annecchino LA, Schultz SR.
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