Results 31 to 40 of about 4,740,049 (320)

Cardiac Transmembrane Ion Channels and Action Potentials: Cellular Physiology and Arrhythmogenic Behavior.

Physiological Reviews, 2020
Cardiac arrhythmias are among the leading causes of mortality. They often arise from alterations in the electrophysiological properties of cardiac cells, and their underlying ionic mechanisms.
A. Varró, J. Tomek, N. Nagy, L. Virág, Elisa Passini, B. Rodríguez, I. Baczkó   +6 more
semanticscholar   +1 more source

DNA looping: the consequences and its control [PDF]

, 2006
The formation of DNA loops by proteins and protein complexes is ubiquitous to many fundamental cellular processes, including transcription, recombination, and replication.
Ackers, Adhya, Alberts, Becker, Bloomfield, Broach, Cloutier, de Lange, Dodd, Du, Dunn, Halford, Hanke, Hill, Irani, Jose MG Vilar, Knight, Leonor Saiz, Lewis, Li, Matthews, Moreau, Mossing, Muller, Müller-Hill, Oehler, Olson, Ptashne, Ptashne, Radman-Livaja, Revet, Richmond, Ringrose, Rippe, Saiz, Saiz, Schleif, Semsey, Stenger, Tolhuis, Vilar, Vilar, Villa, Yan, Yasmin, Zhang   +45 more
core   +1 more source

Whole-cell energy modeling reveals quantitative changes of predicted energy flows in RAS mutant cancer cell lines

iScience, 2023
Summary: Cellular utilization of available energy flows to drive a multitude of forms of cellular “work” is a major biological constraint. Cells steer metabolism to address changing phenotypic states but little is known as to how bioenergetics couples to
Thomas Sevrin, Lisa Strasser, Camille Ternet, Philipp Junk, Miriam Caffarini, Stella Prins, Cian D’Arcy, Simona Catozzi, Giorgio Oliviero, Kieran Wynne, Christina Kiel, Philip J. Luthert   +11 more
doaj   +1 more source

The essential role of mitochondrial dynamics in antiviral immunity. [PDF]

, 2018
Viruses alter cellular physiology and function to establish cellular environment conducive for viral proliferation. Viral immune evasion is an essential aspect of viral persistence and proliferation.
Ahn, Dae-Gyun, Kim, Seong-Jun, Siddiqui, Aleem, Syed, Gulam H   +3 more
core   +2 more sources

Five‐to‐Seven Carbon Glycols Severely Impair Bioenergetics and Metabolism of Aggressive Lung Cancer Cells

Advanced NanoBiomed Research, 2022
Lung cancer is the leading cause of cancer deaths. Nonsmall cell lung cancer (NSCLC) accounts for the vast majority of the histological subtypes and at advanced stage exhibits extremely low survival rate.
Sílvio Terra Stefanello, Caren Rigon Mizdal, Ihab Azzam, Lilly Döhlinger, Andrea Oeckinghaus, Victor Shahin   +5 more
doaj   +1 more source

Contributions of biliary epithelial cells to hepatocyte homeostasis and regeneration in zebrafish

iScience, 2021
Summary: Whether transdifferentiation of the biliary epithelial cells (BECs) to hepatocytes occurs under physiological conditions and contributes to liver homeostasis remains under long-term debate.
Wenfeng Zhang, Jingying Chen, Rui Ni, Qifen Yang, Lingfei Luo, Jianbo He   +5 more
doaj   +1 more source

Microtubule-severing enzymes: From cellular functions to molecular mechanism. [PDF]

, 2018
Microtubule-severing enzymes generate internal breaks in microtubules. They are conserved in eukaryotes from ciliates to mammals, and their function is important in diverse cellular processes ranging from cilia biogenesis to cell division, phototropism ...
Ahmad, Akhmanova, Akhmanova, Allison, Antonina Roll-Mecak, Aubin-Tam, Banks, Barton, Benz, Bichet, Burk, Burk, Carlier, Carlier, Carlier, Charafeddine, Cheung, Chi, Connell, Denton, DeSantis, DesMarais, Dominguez, Dong, Doyle, Dymek, Dymek, Díaz-Valencia, Eckert, Evans, Francis J. McNally, Ganem, Gates, Grode, Guizetti, Han, Hara, Hartman, Hartman, Hawkins, Hazan, Hu, Hu, Iwaya, Jiang, Jiang, Jiang, Johjima, Joly, Kasher, Keating, Lacroix, Lata, Lee, Leo, Lindeboom, Liu, Loughlin, Lundin, Lučič, Maillard, Mains, Mao, Matsuo, McNally, McNally, McNally, McNally, McNally, McNally, Minoura, Mishra-Gorur, Mitchison, Monroe, Moretti, Mukherjee, Murata, Nakamura, Nicklas, Nithianantham, Olivares, Park, Peng, Portis, Puchades, Qiang, Rao, Reid, Rezabkova, Ribbeck, Rogers, Roll-Mecak, Roll-Mecak, Roll-Mecak, Roll-Mecak, Sharma, Sharp, Shaw, Sherwood, Sonbuchner, Srayko, Stamatakis, Stewart, Stone, Tao, Taylor, Ti, Tirnauer, Tran, Trotta, Vale, Valenstein, Vemu, Vemu, Vietri, Walker, Wang, Waterman-Storer, Wen, White, Whitehead, Wightman, Yang, Yang, Yang, Yu, Zehr, Zhang, Zhang, Zhang, Zhao   +130 more
core   +2 more sources

Quinoa husk peptides reduce melanin content via Akt signaling and apoptosis pathways

iScience, 2023
Summary: To improve the treatment of pigmentation disorders, looking for natural and safe inhibitors of melanin synthesis has become an area of research interest. The quinoa husk peptides reportedly elicit various biological activities (e.g., anti-cancer,
Caijing Han, Bingjie Lin, Xinyu Huang, Zhaojie Mao, Xiaoting Kong, Lei Fang, Peng Xue, Anning Wang, Fengxiang Zhang   +8 more
doaj   +1 more source

Electrolyte and Water Balance of the Early Avian Embryo: Effects of Egg Turning [PDF]

, 2002
Formation of sub-embryonic fluid (SEF) is a key aspect of the physiology of the early avian embryo.Here we review the process of SEF formation and the factors which influence its composition and the rate of SEF production and depletion in the Japanese ...
Baggott, Glenn K., Deeming, D.C., Latter, G.V.   +2 more
core   +1 more source

Mitochondrial behaviour throughout the lytic cycle of Toxoplasma gondii [PDF]

, 2017
Mitochondria distribution in cells controls cellular physiology in health and disease. Here we describe the mitochondrial morphology and positioning found in the different stages of the lytic cycle of the eukaryotic single-cell parasite Toxoplasma gondii.
Lemgruber, Leandro, Ovciarikova, Jana, Sheiner, Lilach, Stilger, Krista L., Sullivan, William J.   +4 more
core   +2 more sources