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Techniques for Molecular Imaging Probe Design [PDF]
Molecular Imaging, 2011 Molecular imaging allows clinicians to visualize disease-specific molecules, thereby providing relevant information in the diagnosis and treatment of patients.
Fred Reynolds, Kimberly A. Kelly
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microDuMIP: target-enrichment technique for microarray-based duplex molecular inversion probes [PDF]
Nucleic Acids Research, 2014 Molecular inversion probe (MIP)-based capture is a scalable and effective target-enrichment technology that can use synthetic single-stranded oligonucleotides as probes. Unlike the straightforward use of synthetic oligonucleotides for low-throughput target capture, high-throughput MIP capture has required laborious protocols to generate thousands of ...
Jung-Ki Yoon +7 more
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Gold nanorods as molecular probes for light-based imaging techniques [PDF]
, 2010 The thesis describes the use of gold nanorods as molecular probes for light-based imaging techniques for potential applications in biology and medicine. An overview of the synthesis and critical parameters influencing the synthesis of gold nanorods on size/shape/yield of nanorods are discussed. For using gold nanorods in vivo, the concerns of toxicity,
Raja Gopal Rayavarapu
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Optical probes and techniques for molecular contrast enhancement in coherence imaging [PDF]
Journal of Biomedical Optics, 2005 Optics has played a key role in the rapidly developing field, of molecular imaging. The spectroscopic nature and high-resolution imaging capabilities of light provide a means for probing biological morphology and function at the cellular and molecular levels.
Stephen A. Boppart +3 more
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Probing spatial locality in ionic liquids with the grand canonical adaptive resolution molecular dynamics technique [PDF]
The Journal of Chemical Physics, 2018 We employ the Grand Canonical Adaptive Resolution Simulation (GC-AdResS) molecular dynamics technique to test the spatial locality of the 1-ethyl 3-methyl imidazolium chloride liquid. In GC-AdResS, atomistic details are kept only in an open sub-region of the system while the environment is treated at coarse-grained level; thus, if spatial quantities ...
B. Shadrack Jabes +3 more
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Biophysical Journal, 1995 Adhesion and cytoskeletal structure are intimately related in biological cell function. Even with the vast amount of biological and biochemical data that exist, little is known at the molecular level about physical mechanisms involved in attachments between cells or about consequences of adhesion on the material structure. To expose physical actions at
E. Evans, Ken Ritchie, Rudolf Merkel
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Identification of Mycobacterium kansasii by Using a DNA Probe (AccuProbe) and Molecular Techniques [PDF]
Journal of Clinical Microbiology, 1999 ABSTRACT The newly formulated Mycobacterium kansasii AccuProbe was evaluated, and the results obtained with the new version were compared to the results obtained with the old version of this test by using 116 M. kansasii strains, 1 Mycobacterium gastri strain,
Elvira Richter +3 more
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Inelastic effects in molecular transport junctions: The probe technique at high bias [PDF]
The Journal of Chemical Physics, 2016 We extend the Landauer-Büttiker probe formalism for conductances to the high bias regime and study the effects of environmentally induced elastic and inelastic scattering on charge current in single molecule junctions, focusing on high-bias effects.
Michael Kilgour, Dvira Segal
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Characterization of Nonlinear Molecular Dynamics Using The Double Pump Probe Technique
Frontiers in Optics 2008/Laser Science XXIV/Plasmonics and Metamaterials/Optical Fabrication and Testing, 2008 We performed double pump-probe experiments to study the intra-molecular dynamics of several nonlinear organic dye molecules. The method allows for characterization of triplet states yield and cross-section. Several special cases of molecular dynamics are presented.
Davorin Peceli +10 more
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Charge transport in molecular junctions: From tunneling to hopping with the probe technique [PDF]
The Journal of Chemical Physics, 2015 We demonstrate that a simple phenomenological approach can be used to simulate electronic conduction in molecular wires under thermal effects induced by the surrounding environment. This “Landauer-Büttiker’s probe technique” can properly replicate different transport mechanisms, phase coherent nonresonant tunneling, ballistic behavior, and hopping ...
Michael Kilgour, Dvira Segal
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