Turn-on quinoline probe for selective sensing of hypochlorite in live cells. [PDF]
Olubiyo FF, Klu SYS, Burgess RJ, Hou Y.
europepmc +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Ultrafast and specific miRNA quantification via single-molecule fluorescence quenching kinetics. [PDF]
Kim J, Hohng S.
europepmc +1 more source
Using Enhanced Sampling Molecular Dynamics Techniques to Probe the Thermodynamics of pHLIP Peptide Insertion into a Model Lipid Bilayer [PDF]
Yue Ren, Blake Mertz
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A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
The Lipid Interactome: an interactive and open access platform for exploring cellular lipid-protein interactions. [PDF]
Guzman G +5 more
europepmc +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Editorial: Applications of fluorescence in surgery and diagnostics, volume II: evolution and breakthroughs. [PDF]
Belykh E, Preul MC.
europepmc +1 more source
Molecular self-assembly of conducting polymer by Conducting Probe Technique in Atomic Force Microscope [PDF]
Shin‐ichi Yamamoto, Kazufumi Ogawa
openalex +1 more source

