Results 131 to 140 of about 604,365 (268)

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

Editorial: Development and validation of new molecular probes of nuclear medicine and new targets of nuclear drugs in cancers. [PDF]

Front Oncol
Li W, Wang Z, Chen X, Qin Y, Dai D.
europepmc   +1 more source

MC1R and melanin-based molecular probes for theranostic of melanoma and beyond. [PDF]

Acta Pharmacol Sin, 2022
Shi H, Cheng Z.
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Tuning the efficiency of molecular probes <i>via</i> quinone methide-based <i>in situ</i> labeling. [PDF]

RSC Chem Biol
Rabinowitz Z, Anvar S, Liu J, Chen Z, Zhang Y, Cui C, Sigler A, Cui L.   +7 more
europepmc   +1 more source

Looking deep inside tissue with photoacoustic molecular probes: a review. [PDF]

J Biomed Opt, 2022
Hui X, Malik MOA, Pramanik M.
europepmc   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Sensitive Detection of Intercellular Tensile Forces via Cas12a-Assisted Membrane Molecular Probes. [PDF]

Nano Lett
Singuru MMR, Bhattacharyya P, Sriramakrishnan HP, You M.   +3 more
europepmc   +1 more source

Activated molecular probes for enzyme recognition and detection. [PDF]

Theranostics, 2022
Yuan M, Wu Y, Zhao C, Chen Z, Su L, Yang H, Song J.   +6 more
europepmc   +1 more source