Results 191 to 200 of about 596,923 (316)

Inverse Mixed-Solvent Molecular Dynamics for Visualization of the Residue Interaction Profile of Molecular Probes. [PDF]

Int J Mol Sci, 2022
Yanagisawa K, Yoshino R, Kudo G, Hirokawa T.   +3 more
europepmc   +1 more source

Designing Molecular Probes To Prolong Intracellular Retention: Application to Nitroxide Spin Probes

, 2016
Eric A. Legenzov, Sukumaran Muralidharan, Lukas B. Woodcock, Gareth R. Eaton, Sandra S. Eaton, Gerald M. Rosen, Joseph P. Y. Kao   +6 more
openalex   +1 more source

Probing spatial locality in ionic liquids with the grand canonical adaptive resolution molecular dynamics technique [PDF]

, 2018
B. Shadrack Jabes, Christian Krekeler, Rupert Klein, Luigi Delle Site   +3 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Amphiphilic hemicyanine molecular probes crossing the blood-brain barrier for intracranial optical imaging of glioblastoma. [PDF]

Sci Adv
Qin W, Li H, Chen J, Qiu Y, Ma L, Nie L.
europepmc   +1 more source

Design, synthesis and evaluation of ¹⁵N- and ¹³C-labeled molecular probes as hyperpolarized nitric oxide sensors. [PDF]

Bioorg Med Chem, 2022
Park H, Eriksson S, Warren WS, Wang Q.
europepmc   +1 more source

4-Alkyloxyimino Derivatives of Uridine-5′-triphosphate: Distal Modification of Potent Agonists as a Strategy for Molecular Probes of P2Y₂, P2Y₄, and P2Y₆Receptors [PDF]

, 2014
P. Suresh Jayasekara, Matthew O. Barrett, Christopher B. Ball, Kyle A. Brown, Eva Hammes, Рамачандран Баласубраманиан, T. Kendall Harden, Kenneth A. Jacobson   +7 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Molecular probes for the human adenosine receptors. [PDF]

Purinergic Signal, 2021
Yang X, Heitman LH, IJzerman AP, van der Es D.   +3 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source