Results 21 to 30 of about 631,116 (314)

Rapid generation of chromosome-specific alphoid DNA probes using the polymerase chain reaction [PDF]

open access: yes, 1992
Non-isotopic in situ hybridization of chromosome-specific alphoid DNA probes has become a potent tool in the study of numerical aberrations of specific human chromosomes at all stages of the cell cycle. In this paper, we describe approaches for the rapid
Dunham, Ian   +7 more
core   +1 more source

A biomimetic nanoreactor for synergistic chemiexcited photodynamic therapy and starvation therapy against tumor metastasis

open access: yesNature Communications, 2018
Photodynamic therapy is usually ineffective against deeply seated metastatic tumors due to poor penetration of the excitation light. Here, the authors design a biomimetic nanoreactor which can convert nutriment glucose into toxic singlet oxygen via ...
Zhengze Yu   +4 more
doaj   +1 more source

Recent Advances and Challenges in 2D Metal-Free Electrocatalysts for N2 Fixation

open access: yesFrontiers in Chemistry, 2020
The ever-growing requirement of ammonia for industry and energy supply motivates people to find clean and cost-effective alternatives to overcome the shortcomings of the century-old Haber-Bosch process. Electrocatalytic N2 reduction (NRR) is considered a
Xinyuan Xia   +3 more
doaj   +1 more source

Multivalent Probes in Molecular Imaging: Reality or Future? [PDF]

open access: yes, 2021
The rapidly developing field of molecular medical imaging focuses on specific visualization of (patho)physiological processes through the application of imaging agents (IAs) in multiple clinical modalities.
Elsinga, Philip H.   +3 more
core   +1 more source

Molecular biological methods for studying the gut microbiota : the EU human gut flora project

open access: yes, 2002
Seven European laboratories co-operated in a joint project (FAIR CT97-3035) to develop, refine and apply molecular methods towards facilitating elucidation of the complex composition of the human intestinal microflora and to devise robust methodologies ...
Vos, W.M., de   +5 more
core   +1 more source

Photothermal conversion triggered thermal asymmetric catalysis within metal nanoparticles loaded homochiral covalent organic framework

open access: yesNature Communications, 2019
Achieving both high stereoselectivity and yield is a challenge for conventional asymmetric catalysis. Here, the authors report two metal nanoparticle-loaded and porphyrin-containing homochiral covalent organic framework-based composite catalysts that ...
Hui-Chao Ma   +3 more
doaj   +1 more source

Fabrication of molecular tension probes

open access: yesMethodsX, 2016
A unique bioluminescent imaging probe is introduced for illuminating molecular tension appended by protein-protein interactions (PPIs) of interest. A full-length luciferase is sandwiched between two proteins of interest via minimal flexible linkers.
Kim, Sung Bae, Fujii, Rika
openaire   +2 more sources

Development of mitochondrial SSU rDNA-based oligonucleotide probes for specific detection of common airborne fungi

open access: yes, 2003
In this study we sequenced partial mitochondrial small subunit rDNA from 32 fungal strains representing 31 species from 16 genera. Most of these species are common airborne fungi and pathogens that may cause various public health concerns.
Blomquist, Göran   +2 more
core   +1 more source

A novel spectroscopic probe for molecular chirality [PDF]

open access: yesChirality, 2006
AbstractRecent advances in developing sum frequency generation (SFG) as a novel spectroscopic probe for molecular chirality are reviewed. The basic principle underlying the technique is briefly described, in comparison with circular dichroism (CD). The significantly better sensitivity of the technique than CD is pointed out, and the reason is discussed.
Na, Ji, Yuen-Ron, Shen
openaire   +2 more sources

Conjugated polythiophene probes target lysosome-related acidic vacuoles in cultured primary cells

open access: yes, 2007
Conformation-sensitive optical probes for studying biological processes and structures are of great interest. The present work shows for the first time that conjugated polyelectrolyte (CPE) probes can be used for specific targeting of chromatin, nuclear ...
Jonasson, Jon,   +6 more
core   +1 more source

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