Results 61 to 70 of about 1,842,096 (265)

The collisional excitation of CS by H2O for cometary applications

Astronomy & Astrophysics
Aims. Collisional rate coefficients with H2O as the collisional partner for cometary applications are usually missing from the literature due to the high computational cost of such calculations.
Godard Palluet Amélie, Kłos Jacek, Kędziera Dariusz, Lique François   +3 more
doaj   +1 more source

Screening for clusters of charge in human virus proteomes

BMC Genomics, 2016
Background The identification of charge clusters (runs of charged residues) in proteins and their mapping within the protein structure sequence is an important step toward a comprehensive analysis of how these particular motifs mediate, via electrostatic
Najla Kharrat, Sabrine Belmabrouk, Rania Abdelhedi, Riadh Benmarzoug, Mourad Assidi, Mohammed H. Al Qahtani, Ahmed Rebai   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Experimental investigation of O2 diffusion and entrapment in interstellar amorphous solid water

Astronomy & Astrophysics
Context. Interstellar ices are mainly composed of amorphous solid water (ASW) containing small amounts of hypervolatiles, such as O2, whose diffusion-limited reactions play a key role in space chemistry.
Coulaud L., Santos J. C., Chuang K.-J.
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Molecular Switches as Platforms for Information Processing

CHIMIA, 2014
This article shows how to teach molecules the basics of logic and how to integrate complicated logic operations with relatively simple molecules. A special focus is put on the realization of multi-level fluorescent switches with chemical inputs as well as on the demonstration of various memory-based operations with all-optical photochromic ...
openaire   +5 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Ammonia deuteration mechanism in interstellar conditions

Astronomy & Astrophysics
Aims. We investigate the reaction mechanism of deuterium transfer in the D3+ + NH3 reaction. The distinction between proton hop and full scrambling mechanisms is critical for accurate modeling of deuterated ammonia isotopologs. Methods. The reaction rate
Hernández Alvarez O. E., Rednyk D., Roučka Š., Bondari I., Soboli S., Dohnal P., Plašil R., Glosík J.   +7 more
doaj   +1 more source

Molecular processes as quantum information resources

The Journal of Chemical Physics
In this contribution to Abraham Nitzan’s Festschrift, we present a perspective of theoretical research over the years that has pointed to the potential of molecular processes to act as quantum information resources. Under appropriate control, homonuclear dimer (diatom) dissociation (half-collision) and the inverse process of atom-pair collisions are ...
Saikat Sur, Pritam Chattopadhyay, Gershon Kurizki   +2 more
openaire   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source