Ammonia deuteration mechanism in interstellar conditions
Astronomy & AstrophysicsAims. We investigate the reaction mechanism of deuterium transfer in the D3+ + NH3 reaction. The distinction between proton hop and full scrambling mechanisms is critical for accurate modeling of deuterated ammonia isotopologs. Methods. The reaction rate
Hernández Alvarez O. E. +7 more
doaj +1 more source
Molecular Processes Involved in the Shared Pathways between Cardiovascular Diseases and Diabetes. [PDF]
Biomedicines, 2023 Tokarek J +7 more
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Molecular Processes Leading to Shear Banding in Entangled Polymeric Solutions. [PDF]
Polymers (Basel), 2023 Boudaghi M, Edwards BJ, Khomami B.
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Experimental investigation of O2 diffusion and entrapment in interstellar amorphous solid water
Astronomy & AstrophysicsContext. Interstellar ices are mainly composed of amorphous solid water (ASW) containing small amounts of hypervolatiles, such as O2, whose diffusion-limited reactions play a key role in space chemistry.
Coulaud L., Santos J. C., Chuang K.-J.
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
The collisional excitation of CS by H2O for cometary applications
Astronomy & AstrophysicsAims. Collisional rate coefficients with H2O as the collisional partner for cometary applications are usually missing from the literature due to the high computational cost of such calculations.
Godard Palluet Amélie +3 more
doaj +1 more source
Production of Fungal Pigments: Molecular Processes and Their Applications. [PDF]
J Fungi (Basel), 2022 Lin L, Xu J.
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source