Results 231 to 240 of about 10,169,709 (296)

Effect of Lanthanide Ions and Triazole Ligands on the Molecular Properties, Spectroscopy and Pharmacological Activity. [PDF]

Int J Mol Sci
Alcolea Palafox M, Belskaya NP, Todorov LT, Hristova-Avakoumova NG, Kostova IP.   +4 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Effect of Phosphate on the Molecular Properties, Interactions, and Assembly of Engineered Spider Silk Proteins. [PDF]

Biomacromolecules
Yin Y, Griffo A, Gutiérrez Cruz A, Hähl H, Jacobs K, Linder MB.   +5 more
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Distinguishing Molecular Properties of OAT, OATP, and MRP Drug Substrates by Machine Learning. [PDF]

Pharmaceutics
Nigam AK, Momper JD, Ojha AA, Nigam SK.
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

A Phenomenological Perturbation-like Approach for Prediction of Molecular Properties in Large Libraries of Polysubstituted Derivatives: Application to Molecular Solar Thermal Systems. [PDF]

J Chem Theory Comput
Peinado A, Jodra A, Cebrián C, Frutos LM.   +3 more
europepmc   +1 more source

Molecular Properties of Virulence and Antibiotic Resistance of <i>Pseudomonas aeruginosa</i> Causing Clinically Critical Infections. [PDF]

Pathogens
Monroy-Pérez E, Herrera-Gabriel JP, Olvera-Navarro E, Ugalde-Tecillo L, García-Cortés LR, Moreno-Noguez M, Martínez-Gregorio H, Vaca-Paniagua F, Paniagua-Contreras GL.   +8 more
europepmc   +1 more source

Molecular properties of a triazole-Ce(III) complex with antioxidant activity: structure, spectroscopy, and relationships with related derivatives. Influence of the ligands in the complex. [PDF]

Front Chem
Palafox MA, Belskaya NP, Todorov L, Hristova-Avakumova N, Kostova IP.   +4 more
europepmc   +1 more source

Elucidating the molecular properties and anti-mycobacterial activity of cysteine peptidase domain of D29 mycobacteriophage endolysin. [PDF]

J Virol
Gangakhedkar R, Jain V.
europepmc   +1 more source