Results 281 to 290 of about 5,894,644 (362)

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

Molecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul, François Guillonneau, Odile Blanchet, Hamza Lasla, Audrey Rousseau, Catherine Guette, Alice Boissard, Cécile Henry, Morgan Dhondt, Pascal Jézéquel, Philippe Menei, Jean‐Michel Lemée   +11 more
wiley   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Continuous clinicopathological and molecular recognition of very virulent infectious bursal disease virus in commercial broiler chickens. [PDF]

Poult Sci
Setta A, Yehia N, Shaheen M, Shami A, Al-Saeed FA, Alsamghan A, Amin R, El-Saadony MT, El-Tarabily KA, Salem HM.   +9 more
europepmc   +1 more source

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Molecular Recognition in Water Using Macrocyclic Synthetic Receptors

Chemical Reviews, 2021
Molecular recognition in water using macrocyclic synthetic receptors constitutes a vibrant and timely research area of supramolecular chemistry. Pioneering examples on the topic date back to the 1980s.
Luis Escobar, Pablo Ballester
exaly   +2 more sources

Novel Porous Crystals with Macrocycle-Based Well-Defined Molecular Recognition Sites.

Accounts of Chemical Research, 2020
Molecular recognition is one of the fundamental events in biological systems, as typified by enzymes that enable highly efficient and selective catalytic reactions through precise recognition of substrate(s) and cofactor(s) in the binding pockets ...
S. Tashiro, M. Shionoya
semanticscholar   +1 more source

Nucleoside Analogue-Based Supramolecular Nanodrugs Driven by Molecular Recognition for Synergistic Cancer Therapy.

Journal of the American Chemical Society, 2018
The utilization of nanotechnology for the delivery of a wide range of anticancer drugs has the potential to reduce adverse effects of free drugs and improve the anticancer efficacy. However, carrier materials and/or chemical modifications associated with
Dali Wang, Chunyang Yu, Li Xu, Leilei Shi, Gangsheng Tong, Jieli Wu, Hong Liu, D. Yan, Xinyuan Zhu   +8 more
semanticscholar   +1 more source

Molecular Recognition with Resorcin[4]arene Cavitands: Switching, Halogen-Bonded Capsules, and Enantioselective Complexation.

Journal of the American Chemical Society, 2018
The development of synthetic host-guest chemistry to investigate and quantify weak, non-covalent interactions has been key to unraveling the complexity of molecular recognition in chemical and biological systems.
Cornelius Gropp, Brendan L. Quigley, F. Diederich   +2 more
semanticscholar   +1 more source

Confinement of Aggregation-Induced Emission Molecular Rotors in Ultrathin Two-Dimensional Porous Organic Nanosheets for Enhanced Molecular Recognition.

Journal of the American Chemical Society, 2018
Despite the rapid development of molecular rotors over the past decade, it still remains a huge challenge to understand their confined behavior in ultrathin two-dimensional (2D) nanomaterials for molecular recognition. Here, we report an all-carbon, 2D π-
Jinqiao Dong, Xu Li, Kang Zhang, Yi Di Yuan, Yuxiang Wang, Linzhi Zhai, Guoliang Liu, Daqiang Yuan, Jianwen Jiang, Dan Zhao   +9 more
semanticscholar   +1 more source