Results 21 to 30 of about 894,051 (294)
Beilstein Journal of Organic Chemistry, 2022 A series of tetraamino-bisthiourea chiral macrocycles containing two diarylthiourea and two chiral diamine units were synthesized by a fragment-coupling approach in high yields.
Hao Guo +3 more
doaj +1 more source
Spiralling molecular structures and chiral selectivity in model membranes [PDF]
, 2023 Since the lipid raft model was developed at the end of the last century, it became clear that the specific molecular arrangements of phospholipid assemblies within a membrane have profound implications in a vast range of physiological functions. Studies of such condensed lipid islands in model systems using fluorescence and Brewster angle microscopies ...
arxiv +1 more source
Photoredox cooperative N-heterocyclic carbene/palladium-catalysed alkylacylation of alkenes
Nature Communications, 2022 Three-component carboacylation of simple alkenes often requires directing groups and strained substrates. Here, the authors report a photoredox N-heteroyclic carbene/Pd-catalysed alkylacylation of alkenes with aldehydes and unactivated alkyl halides ...
You-Feng Han +5 more
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Optimal Design of a Molecular Recognizer: Molecular Recognition as a Bayesian Signal Detection Problem [PDF]
IEEE Journal of Selected Topics in Signal Processing, vol. 2,
issue 3, pp. 390-399, 2008, 2010 Numerous biological functions-such as enzymatic catalysis, the immune response system, and the DNA-protein regulatory network-rely on the ability of molecules to specifically recognize target molecules within a large pool of similar competitors in a noisy biochemical environment.
arxiv +1 more source
Nature Communications, 2018 Gamma-butyrolactones are widespread in Nature, however direct catalytic methods to access them are limited. Here, the authors report a gold-catalyzed cycloisomerization of allenoic acids to acces γ-butyrolactones and apply it to the asymmetric synthesis ...
Jing Zhou, Chunling Fu, Shengming Ma
doaj +1 more source
The physical language of molecular codes: A rate-distortion approach to the evolution and emergence of biological codes [PDF]
Workshop on Biological and Bio-Inspired Information Theory, 43rd
Annual Conference on Information Sciences and Systems, March 18-20, 2009 2009
, Page(s): 841 - 846, 2010 The function of the organism hinges on the performance of its information-processing networks, which convey information via molecular recognition. Many paths within these networks utilize molecular codebooks, such as the genetic code, to translate information written in one class of molecules into another molecular "language" .
arxiv +1 more source
Molecular recognition in a lattice model: An enumeration study [PDF]
Phys. Rev. Lett. 93, 268108 (2004), 2005 We investigate the mechanisms underlying selective molecular recognition of single heteropolymers at chemically structured planar surfaces. To this end, we study systems with two-letter (HP) lattice heteropolymers by exact enumeration techniques. Selectivity for a particular surface is defined by an adsorption energy criterium.
arxiv +1 more source
A Coarse-Grained Lattice Model for Molecular Recognition [PDF]
Phys. Rev. Lett. 97, 128101 (2006), 2006 We present a simple model which allows to investigate equilibrium aspects of molecular recognition between rigid biomolecules on a generic level. Using a two-stage approach, which consists of a design and a testing step, the role of cooperativity and of varying bond strength in molecular recognition is investigated.
arxiv +1 more source
A 3D-Shape Similarity-based Contrastive Approach to Molecular Representation Learning [PDF]
arXiv, 2022 Molecular shape and geometry dictate key biophysical recognition processes, yet many graph neural networks disregard 3D information for molecular property prediction. Here, we propose a new contrastive-learning procedure for graph neural networks, Molecular Contrastive Learning from Shape Similarity (MolCLaSS), that implicitly learns a three ...
arxiv
Nature Communications, 2023 Direct synthesis of ketones from aldehydes features high atom- and step-economy. Yet, the coupling of aldehydes with unactivated alkyl C(sp3)-H remains challenging.
Hai-Ying Wang +4 more
doaj +1 more source