Results 81 to 90 of about 5,099,016 (263)

TarO : a target optimisation system for structural biology [PDF]

, 2008
This work was funded by the UK Biotechnology and Biological Sciences Research Council (BBSRC) Structural Proteomics of Rational Targets (SPoRT) initiative, (Grant BBS/B/14434).
Naismith, Jim, Barton, Geoffrey J, Naismith, James H, William N. Hunter, White, Malcolm F, McMahon, Stephen, Hunter, William N., vanNiekerk, C. A. Johannes, Overton, Ian M., Hunter, William, van Niekerk, C. A. Johannes, van Niekerk, C A, Barton, Geoffrey, Carter, Lester, Geoffrey J. Barton, Naismith, James, Hunter, W N, Carter, Lester G., Overton, Ian; id_orcid, Dawson, Alice, McMahon, S A, Dawson, A, David M. A. Martin, McMahon, Stephen A., White, Malcolm F., Martin, David, Scott Cameron, White, Malcolm, Barton, G J, Cameron, Scott, Naismith, James H., Ian M. Overton, James H. Naismith, Cameron, S, Malcolm F. White, Barton, Geoffrey J.; id_orcid, Lester G. Carter, Carter, L G, Alice Dawson, Martin, D M, Martin, David M. A.; id_orcid, C. A. Johannes Van Niekerk, Stephen A. Mcmahon, Overton, I M, Overton, Ian   +44 more
core   +1 more source

Hayai-Annotation: A functional gene prediction tool that integrates orthologs and gene ontology for network analysis in plant species

Computational and Structural Biotechnology Journal
Hayai-Annotation, an annotation tool powered by the R-shinydashboard browser interface, implements a workflow that integrates sequence alignment using DIAMOND against UniProtKB Plants and ortholog inference using OrthoLoger. We here propose a pipeline to
Andrea Ghelfi, Sachiko Isobe
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Sequencing, annotation, and comparative genome analysis of the gerbil-adapted Helicobacter pylori strain B8 [PDF]

, 2010
Farnbacher M, Jahns T, Willrodt D, et al. Sequencing, annotation, and comparative genome analysis of the gerbil-adapted Helicobacter pylori strain B8. BMC Genomics.
Haas, Rainer, Rainer Haas, Farnbacher, Max, Rieder Gabriele, Goesmann, Alexander ; https://orcid.org/, Farnbacher Max, Kurtz, Stefan, Rieder, Gabriele, Kurtz Stefan, Gabriele Rieder, Alexander Goesmann, Rolf Daniel, Daniel, Rolf, Willrodt Dirk, Dirk Willrodt, Max Farnbacher, Jahns, Thomas, Goesmann Alexander, Haas Rainer, Goesmann, Alexander, Thomas Jahns, Stefan Kurtz, Daniel Rolf, Willrodt, Dirk, Jahns Thomas, Gabriele, Rieder   +25 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Complete genome sequence of Rhizobium leguminosarum bv. trifolii strain WSM1325, an effective microsymbiont of annual Mediterranean clovers [PDF]

, 2010
Rhizobium leguminosarum bv trifolii is a soil-inhabiting bacterium that has the capacity to be an effective nitrogen fixing microsymbiont of a diverse range of annual Trifolium (clover) species.
Alex Copeland, John Howieson, Mavromatis, K, Cliff Han, Nolan, M, Victor Markowitz, Nandasena, K.G., Konstantinos Mavromatis, Ovchinikova, G, Lambert Bräu, Natalia Ivanova, Ardley, J.K., Wayne Reeve, Ardley, J, Patrick Chain, Bräu, L, Melino, V, Denton, M., Chain, P., Nandesena, K, Yates, R, Copeland, A., Melino, V., Ivanova, N, Ravi Tiwari, Ivanova, N., Graham O’Hara, Nandesena, K., O'Hara, G, Yates, R.J., Yates, R., Julie Ardley, Brettin, T., Kyrpides, N., Copeland, A, et al., Markowitz, V., Vanessa Melino, Reeve, W.G., O'Hara, G.W., Nolan, M., Miriam Land, Han, Cliff, Matthew Denton, Tiwari, R., Nikos Kyrpides, Matt Nolan, Thomas Brettin, Tiwari, R, Reeve, W., Han, C, Han, C., Reeve, W, Land, M., O'Hara, G., Ron Yates, Denton, M, Kemanthi Nandesena, Howieson, J, Mavromatis, K., Ardley, J., Galina Ovchinikova, Chain, P, Kyrpides, N, Ovchinikova, G., Land, M, Brettin, T, Howieson, J., Markowitz, V, Bräu, L.   +69 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Short read Illumina data for the de novo assembly of a non-model snail species transcriptome (Radix balthica, Basommatophora, Pulmonata), and a comparison of assembler performance [PDF]

, 2011
Background: Until recently, read lengths on the Solexa/Illumina system were too short to reliably assemble transcriptomes without a reference sequence, especially for non-model organisms.
Wheat, Christopher W., Markus Pfenninger, Rotter, Björn, Pfenninger, Markus, Björn Rotter, Christopher W Wheat, Nicolas Krezdorn, Feldmeyer, Barbara, Krezdorn, Nicolas, Rotter, Bjoern, Barbara Feldmeyer   +10 more
core   +2 more sources

Complete genome sequence data of multidrug-resistant Aeromonas veronii strain MS-18-37

Data in Brief, 2019
Aeromonas are Gram-negative, non-spore forming rods belonging to the family Aeromonadaceae within the class Gammaproteobacteria. These facultative anaerobic bacteria are ubiquitous in aquatic environments and have a broad host range.
Hossam Abdelhamed, Mark L. Lawrence, Geoffrey Waldbieser   +2 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source