Results 161 to 170 of about 4,241,168 (373)

Molecular epidemiology of mumps viruses in the Netherlands, 2017-2019

open access: yesPLoS ONE, 2020
Mumps cases continue to occur, also in countries with a relatively high vaccination rate. The last major outbreaks of mumps in the Netherlands were in 2009–2012 and thereafter, only small clusters and single cases were reported.
Rogier Bodewes   +7 more
doaj  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Molecular characterisation of lineage IV peste des petits ruminants virus using multi gene sequence data

open access: hybrid, 2014
Senthil Kumar Karuppannan   +12 more
openalex   +1 more source

Species Molecular Barcode Analysis with Nanopore Sequence Data v1

open access: yes
End-to-end workflow to generate cleaned consensus sequences from multiplexed amplicons sequenced with Nanopore sequencing technology. Includes read basecalling, quality control, data filtering, read demultiplexing, consensus sequence generation, and a data summary.
Gideon Erkenswick   +4 more
openaire   +1 more source

DnaSP 6: DNA Sequence Polymorphism Analysis of Large Data Sets.

open access: yesMolecular biology and evolution, 2017
J. Rozas   +6 more
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

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