Results 201 to 210 of about 1,789,006 (261)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Genomic characterisation of extensively drug-resistant Acinetobacter baumannii isolates from a tertiary hospital in Ghana. [PDF]

PLoS One
Ashley-Agbedor IE, Mahazu S, Kotey FCN, Amedior J, Adu B, Darko E, Kwao P, Dayie NTKD, Ablordey AS, Opintan JA.   +9 more
europepmc   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

The first dataset of de novo assembled transcriptome of Aspidiotus destructor Signoret (Hemiptera: Diaspididae). [PDF]

Data Brief
Geronca J, Egana JMC, Cleofe MAS, Bautista MAM.   +3 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Dataset on intergenic spacer sequences of the chloroplast genome and potential DNA barcodes of <i>Adinandra glischroloma</i> Hand.-Mazz. from Vietnam. [PDF]

Data Brief
Pho HTT, Nguyen NTT, Sy TD, Nguyen QH, Chu MH.   +4 more
europepmc   +1 more source

RUMINA: high-throughput deduplication of unique molecular identifiers for amplicon and whole-genome sequencing with enhanced error correction. [PDF]

Bioinformatics
Piliper E, Goya S, Greninger AL.
europepmc   +1 more source

Artificial intelligence-enabled multi-scale virtual cell: perspective, challenges, and opportunities. [PDF]

Brief Bioinform
Jiang H, Huang X, Bi X, Ma W, Ni H, Wei Z, Sun P, Zhang H, Zhang S.   +8 more
europepmc   +1 more source

Molecular Detection and Characterization of Orf Virus in Goats With Clinical Signs From Four Districts of Tanzania. [PDF]

Vet Med Sci
Mayenga C, Mwanandota JJ, Marisa J, Gelaye E, Misinzo G.   +4 more
europepmc   +1 more source