Results 241 to 250 of about 2,847,669 (316)

Mitogenomes of mosquito species of Harris County in Texas. [PDF]

Sci Rep
Ali RLMN, Gauthier C, Verde J, Rezaei H, Pritts K, Vigilant M, Nash B, Henriquez B, Vela J, Saldaña MA, Frost SDW, Jackson E, Reddy M, Hoyer I, Pipas JM, Norris DE.   +15 more
europepmc   +1 more source

P-2334. Clesrovimab Binding Site Conservation on the RSV F Protein: An Evaluation of RSV Molecular Sequencing Data from 2019-2023 and GenBank Sequence Analysis

Arthur Fridman, Latisha Love‐Gregory, Radha Railkar, Diane Levitan, Julie Strizki, Kalpit A. Vora   +5 more
openalex   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Sequences Data from : "Large variation in the ratio of mitochondrial to nuclear mutation rate across animals : implications for genetic diversity and the use of mitochondrial DNA as a molecular marker"

, 2017
Rémi Allio, Stefano Donegà, Nicolas Galtier, Benoît Nabholz   +3 more
openalex   +2 more sources

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

FINCHES: A Computational Framework for Predicting Intermolecular Interactions in Intrinsically Disordered Proteins. [PDF]

Int J Mol Sci
Niazi SK.
europepmc   +1 more source

PhyloSuite: an integrated and scalable desktop platform for streamlined molecular sequence data management and evolutionary phylogenetics studies

, 2018
Dong Zhang, Fangluan Gao, Wen X. Li, Ivan Jakovlić, Hong Zou, Jin Zhang, Gui T. Wang   +6 more
openalex   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Harnessing protein language model for structure-based discovery of highly efficient and robust PET hydrolases. [PDF]

Nat Commun
Wu B, Zhong B, Zheng L, Huang R, Jiang S, Li M, Hong L, Tan P.   +7 more
europepmc   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source