Results 71 to 80 of about 1,866,758 (264)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Bayesian sequence learning for predicting protein cleavage points

, 2005
A challenging problem in data mining is the application of efficient techniques to automatically annotate the vast databases of biological sequence data.
Michael Mayo, Mayo, Michael
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

The RNA Ontology (RNAO): An ontology for integrating RNA sequence and structure data

, 2009
Biomedical Ontologies are intended to integrate diverse biomedical data to enable intelligent data-mining and facilitate translation of basic research into useful clinical knowledge.
Eric Westhof, Chris Mungall, Jane Richardson, Karen Eilbeck, Thomas Bittner, Colin Batchelor, Craig Zirbel, Jesse Stombaugh, Neocles Leontis, Rob Knight   +9 more
core  

Prospecting environmental mycobacteria: combined molecular approaches reveal unprecedented diversity [PDF]

, 2013
Background: Environmental mycobacteria (EM) include species commonly found in various terrestrial and aquatic environments, encompassing animal and human pathogens in addition to saprophytes.
Tanya T Khera, Girum Erenso, Dowd Scot E., Orin Courtenay (103643), Brian B Oakley, Abraham Aseffa (108981), Courtenay, Orin, Tanya T. Khera (434872), Girum Erenso (434873), Khera, Tanya T., Aseffa, Abraham, Elizabeth M H Wellington, Elizabeth M. H. Wellington (325617), Mason, Sam, Erenso, Girum, Wellington Elizabeth M. H., Oakley Brian B., Travis, Emma Rachel, Alessandra Pontiroli, Scot E. Dowd (107356), Oakley, Brian B., Emma R Travis, Mason Sam, Dowd, Scot E., Brian B. Oakley (161508), Travis Emma R., Orin Courtenay, Sam Mason (226800), Aseffa Abraham, Erenso Girum, Sam Mason, Pontiroli, Alessandra, Scot E Dowd, Alessandra Pontiroli (226781), Khera Tanya T., Pontiroli Alessandra, Courtenay Orin, Emma R. Travis (339655), Wellington, E. M. H., Abraham Aseffa   +39 more
core   +1 more source

Impact of molecular sequence data completeness on HIV cluster detection and a network science approach to enhance detection. [PDF]

Sci Rep, 2022
Mazrouee S, Hallmark CJ, Mora R, Del Vecchio N, Carrasco Hernandez R, Carr M, McNeese M, Fujimoto K, Wertheim JO.   +8 more
europepmc   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

OrthoSelect: a protocol for selecting orthologous groups in phylogenomics [PDF]

, 2009
Background: Phylogenetic studies using expressed sequence tags (EST) are becoming a standard approach to answer evolutionary questions. Such studies are usually based on large sets of newly generated, unannotated, and error-prone EST sequences from ...
Schreiber Fabian, Fabian Schreiber, Morgenstern Burkhard, Erpenbeck Dirk, Pik, Kerstin, Pick, Kerstin, Morgenstern, Burkhard, Kerstin Pick, Schreiber, Fabian, Wörheide, Gert, Erpenbeck, Dirk, Burkhard Morgenstern, Wörheide Gert, Gert Wörheide, Dirk Erpenbeck, Woerheide, Gert, Pick Kerstin   +16 more
core   +1 more source

rbcL Gene in Global Molecular Data Repository

, 2022
The data in this article gives an overview of the total number of plant species, families, with the rbcL gene sequence in the GenBank and the regions that have contributed to the growth of the rbcL sequence in the repository.
onuselogu, C (via Mendeley Data)
core   +1 more source