Results 81 to 90 of about 2,920,533 (298)

Predictions of structural elements for the binding of Hin recombinase with the hix site of DNA [PDF]

, 1989
Molecular dynamics simulations were coupled with experimental data from biochemistry and genetics to generate a theoretical structure for the binding domain of Hin recombinase complexed with the hix site of DNA.
Goddard, William A., III, Mathiowetz, Alan M., Plaxco, Kevin W.   +2 more
core  

Bayesian variable selection and data integration for biological regulatory networks [PDF]

, 2006
A substantial focus of research in molecular biology are gene regulatory networks: the set of transcription factors and target genes which control the involvement of different biological processes in living cells.
Chen, Guang, Jensen, Shane T., Stoeckert, Jr, Christian J.   +2 more
core   +6 more sources

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Phylogenetic mixtures: Concentration of measure in the large-tree limit [PDF]

, 2012
The reconstruction of phylogenies from DNA or protein sequences is a major task of computational evolutionary biology. Common phenomena, notably variations in mutation rates across genomes and incongruences between gene lineage histories, often make it ...
Mossel, Elchanan, Roch, Sebastien
core   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

A novel method to assess the integrity of frozen archival DNA samples: Alpha‐diversity ratios of short‐ and long‐read 16S rRNA gene sequences

Methods in Ecology and Evolution
Archival DNA samples collected and analysed for a range of research and applied questions have accumulated in the laboratories of universities, government agencies and commercial service providers for decades. These DNA archives represent a valuable, yet
K. M. Sumby, J. R. Stephen, J. J. Austin, R. K. Schilling, T. R. Cavagnaro   +4 more
doaj   +1 more source

GenFlow: generic flow for integration, management and analysis of molecular biology data

Genetics and Molecular Biology, 2004
A large number of DNA sequencing projects all over the world have yielded a fantastic amount of data, whose analysis is, currently, a big challenge for computational biology.
Marcio Katsumi Oikawa, Marcos Eduardo Bolelli Broinizi, Alexandre Dermargos, Hugo Aguirre Armelin, João Eduardo Ferreira   +4 more
doaj   +1 more source

First molecular phylogenetic insights into the evolution of Eriocaulon (Eriocaulaceae, Poales) [PDF]

, 2019
Eriocaulon is a genus of c. 470 aquatic and wetland species of the monocot plant family Eriocaulaceae. It is widely distributed in Africa, Asia and America, with centres of species richness in the tropics.
Barfod, Anders S, Cho, Seong-Hyun, Gale, Stephan W, Ito, Yu, Jobson, Richard W, Kim, Young-Dong, Larridon, Isabel, Li, Jie, Liang, Yuxi, Mesterházy, Attila, Muasya, A Muthama, Newman, Mark F, Parnell, John AN, Phillips, Sylvia M, Prajaksood, Amornrat, Shutoh, Kohtaroh, Souladeth, Phetlasy, Tagane, Shuichiro, Tanaka, Nobuyuki, Tanaka, Norio, Yano, Okihito   +20 more
core   +2 more sources

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source