Results 71 to 80 of about 73,361 (307)

Templated mesoporous materials: expectations, facts and challenges [PDF]

open access: yes, 2010
This presentation included an overview of the main types of the mesoporous structures that can be generated via template processes, addressing the role of surface chemistry on their formation and implications in their properties and applications.
Ribeiro Carrott, M.M.L.
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Efeitos da incorporação de peneiras moleculares 3A, 4A, 5A e 13X em membranas compósitas de quitosana/poli(vinil álcool) Effect of molecular sieves 3A, 4A, 5A and 13X incorporation on the chitosan/poly(vinyl alcohol) composites membranes

open access: yesQuímica Nova, 2010
The composite membranes prepared via incorporation of 12.5% of molecular sieves 3A, 4A, 5A and 13X into chitosan/poly(vinyl alcohol) (1:1). The composite membranes were immersed in the cross-linker sulfuric acid in order to acquire high proton ...
Denice Schulz Vicentini   +2 more
doaj   +1 more source

Space station molecular sieve development [PDF]

open access: yes
An essential function of a space environmental control system is the removal of carbon dioxide (CO2) from the atmosphere to control the partial pressure of this gas at levels lower than 3 mm Hg.
Chang, C., Rousseau, J.
core   +1 more source

Isotope (14C and 13C) analysis of deep peat CO2 using a passive sampling technique [PDF]

open access: yes, 2009
We developed and tested a new method to collect CO<sub>2</sub> from the surface to deep layers of a peatland for radiocarbon analysis. The method comprises two components: i) a probe equipped with a hydrophobic filter that allows entry of ...
Garnett, M.H., Hardie, S.M.L.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Tamices moleculares que combinan micro y meso porosidad: una revisión [PDF]

open access: yesAvances en Química, 2009
Molecular sieves combining micro and mesoporosity: a review. A review of molecular sieves combining micro and mesoporosity is presented. A summary of different routes employed for the preparation of these solids, is showed by citing recent works reported
Carmen M. López*   +3 more
doaj  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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