Results 61 to 70 of about 4,989,468 (303)

Label-free neuroimaging in vivo using synchronous angular scanning microscopy with single-scattering accumulation algorithm

open access: yesNature Communications, 2019
A major challenge of in vivo imaging is imaging deeper, including in turbid tissue. The authors report an adaptive optics based microscope that uses coherent single scattering signal to reduce sample-induced aberrations and enable fast deep-tissue ...
Moonseok Kim   +10 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Spectroscopy Today: The Urgent Need For Science And Innovation To Save This Warming Planet [PDF]

open access: yes, 2022
In this year that we celebrate the 75th anniversary of the International Symposium on Molecular Spectroscopy we find ourselves on a very different planet.
Richmond, Geraldine
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

4D Single-particle tracking with asynchronous read-out single-photon avalanche diode array detector

open access: yesNature Communications
Single-particle tracking techniques enable investigation of the complex functions and interactions of individual particles in biological environments. Many such techniques exist, each demonstrating trade-offs between spatiotemporal resolution, spatial ...
Andrea Bucci   +8 more
doaj   +1 more source

Near-field transmission matrix microscopy for mapping high-order eigenmodes of subwavelength nanostructures

open access: yesNature Communications, 2020
Nanoscale integrated photonic devices have complicated combinations of optical eigenmodes. Here, the authors develop a far- to near-field transmission matrix microscopy that enables measuring higher-order modes of nanostructures beyond the capabilities ...
Eunsung Seo   +9 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Quantum optical measurements with undetected photons through vacuum field indistinguishability

open access: yesScientific Reports, 2017
Quantum spectroscopy and imaging with undetected idler photons have been demonstrated by measuring one-photon interference between the corresponding entangled signal fields from two spontaneous parametric down conversion (SPDC) crystals.
Sun Kyung Lee   +2 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Control of randomly scattered surface plasmon polaritons for multiple-input and multiple-output plasmonic switching devices

open access: yesNature Communications, 2017
Losses of bandwidth are inevitable when interfacing between optical and electronic components. Here the authors present a switching device consisting of a two-dimensional disordered array of nanoholes that can potentially transfer information about 40 ...
Wonjun Choi   +6 more
doaj   +1 more source

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