Results 61 to 70 of about 4,733,523 (302)

LASER IONIZATION SPECTROSCOPY OF AcF AND KING-PLOT ANALYSIS OF MOLECULAR ISOTOPE SHIFTS [PDF]

open access: yes, 2023
The research potential of radioactive molecules for both fundamental and applied science has recently been recognized and significant progress has been marked at ISOLDE on both the production and the spectroscopy of radioactive molecules.
Athanasakis-Kaklamanakis, Michail
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Infrared Diffusion-Ordered Spectroscopy Reveals Molecular Size and Structure [PDF]

open access: yes, 2023
Inspired by ideas from NMR, we have developed Infrared Diffusion-Ordered Spectroscopy (IR-DOSY), which simultaneously characterizes molecular structure and size.
Federico Caporaletti   +16 more
core   +2 more sources

4D Single-particle tracking with asynchronous read-out single-photon avalanche diode array detector

open access: yesNature Communications
Single-particle tracking techniques enable investigation of the complex functions and interactions of individual particles in biological environments. Many such techniques exist, each demonstrating trade-offs between spatiotemporal resolution, spatial ...
Andrea Bucci   +8 more
doaj   +1 more source

Label-free neuroimaging in vivo using synchronous angular scanning microscopy with single-scattering accumulation algorithm

open access: yesNature Communications, 2019
A major challenge of in vivo imaging is imaging deeper, including in turbid tissue. The authors report an adaptive optics based microscope that uses coherent single scattering signal to reduce sample-induced aberrations and enable fast deep-tissue ...
Moonseok Kim   +10 more
doaj   +1 more source

Near-field transmission matrix microscopy for mapping high-order eigenmodes of subwavelength nanostructures

open access: yesNature Communications, 2020
Nanoscale integrated photonic devices have complicated combinations of optical eigenmodes. Here, the authors develop a far- to near-field transmission matrix microscopy that enables measuring higher-order modes of nanostructures beyond the capabilities ...
Eunsung Seo   +9 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Ultrasensitive nonlinear vibrational spectroscopy of complex molecular systems [PDF]

open access: yes, 2017
In this work we use polarization-resolved pump-probe and two-dimensional infrared (2DIR) spectroscopy to study the conformational changes and the vibrational population dynamics in complex molecular systems.
Selig, O.
core   +13 more sources

Quantum optical measurements with undetected photons through vacuum field indistinguishability

open access: yesScientific Reports, 2017
Quantum spectroscopy and imaging with undetected idler photons have been demonstrated by measuring one-photon interference between the corresponding entangled signal fields from two spontaneous parametric down conversion (SPDC) crystals.
Sun Kyung Lee   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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