Results 71 to 80 of about 19,554,258 (410)

High carrier mobility and strong fluorescence emission: Toward highly sensitive single‐crystal organic phototransistors

open access: yesAggregate, 2023
Organic single crystals (OSCs) offer a unique combination of both individual and collective properties of the employed molecules, but it remains highly challenging to achieve OSCs with both high mobilities and strong fluorescence emissions for their ...
Jingwei Tao   +8 more
doaj   +1 more source

Molecular Structure of Galactokinase [PDF]

open access: yesJournal of Biological Chemistry, 2003
Galactokinase plays a key role in normal galactose metabolism by catalyzing the ATP-dependent phosphorylation of alpha-D-galactose to galactose 1-phosphate. In humans, mutations in the galactokinase gene can lead to the diseased state referred to as Type II galactosemia. Here we describe the three-dimensional structure of galactokinase from Lactococcus
Hazel M. Holden, James B. Thoden
openaire   +3 more sources

Jahn-Teller distortion in Cs4C60 studied by vibrational spectroscopy [PDF]

open access: yes, 2002
We have measured the infrared spectra of Cs(4)C(60) in the temperature range 220 - 450 K. Two anomalies in the low-frequency modes at 270 K and 400 K point to changes in molecular or crystal structure.
Borondics, Ferenc   +4 more
core   +1 more source

Searching molecular structure databases with tandem mass spectra using CSI:FingerID

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2015
Significance Untargeted metabolomics experiments usually rely on tandem MS (MS/MS) to identify the thousands of compounds in a biological sample. Today, the vast majority of metabolites remain unknown.
Kai Dührkop   +4 more
semanticscholar   +1 more source

Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones

open access: yesFEBS Letters, EarlyView.
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley   +1 more source

Preoperative assessment of cardiovascular risk in patients undergoing noncardiac surgery: the Orion study

open access: yesMonaldi Archives for Chest Disease, 2020
In patients undergoing noncardiac surgery risk indices can estimate patients’ perioperative risk of major cardiovascular complications. The indexes currently in use were derived from observational studies that are now outdated with respect to the current
Giampaolo Scorcu   +9 more
doaj   +1 more source

Unique adipose tissue invariant natural killer T cell subpopulations control adipocyte turnover in mice

open access: yesNature Communications, 2023
Adipose tissue invariant natural killer T (iNKT) cells are a crucial cell type for adipose tissue homeostasis in obese animals. However, heterogeneity of adipose iNKT cells and their function in adipocyte turnover are not thoroughly understood.
Sang Mun Han   +15 more
doaj   +1 more source

MolFM: A Multimodal Molecular Foundation Model [PDF]

open access: yesarXiv, 2023
Molecular knowledge resides within three different modalities of information sources: molecular structures, biomedical documents, and knowledge bases. Effective incorporation of molecular knowledge from these modalities holds paramount significance in facilitating biomedical research.
arxiv  

Molecular structure of the ATP-bound, phosphorylated human CFTR

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance Mutations in cystic fibrosis transmembrane conductance regulator (CFTR) cause cystic fibrosis, a lethal genetic disease occurring in people of northern European descent. Decades of study have been directed toward a molecular understanding of
Zhe Zhang, Fangyu Liu, Jue Chen
semanticscholar   +1 more source

Structural and mechanistic basis for the regulation of the chloroplast signal recognition particle by (p)ppGpp

open access: yesFEBS Letters, EarlyView.
LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra   +7 more
wiley   +1 more source

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