Results 71 to 80 of about 19,367,956 (387)

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Observation of a shape resonance of the positronium negative ion

open access: yesNature Communications, 2016
The Positronium negative ion is formed by two electrons bound to a positron, and experimental investigations of its states and energy levels are difficult due to its short lifetime.
Koji Michishio   +8 more
doaj   +1 more source

Unique adipose tissue invariant natural killer T cell subpopulations control adipocyte turnover in mice

open access: yesNature Communications, 2023
Adipose tissue invariant natural killer T (iNKT) cells are a crucial cell type for adipose tissue homeostasis in obese animals. However, heterogeneity of adipose iNKT cells and their function in adipocyte turnover are not thoroughly understood.
Sang Mun Han   +15 more
doaj   +1 more source

Molecular structure of the ATP-bound, phosphorylated human CFTR

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance Mutations in cystic fibrosis transmembrane conductance regulator (CFTR) cause cystic fibrosis, a lethal genetic disease occurring in people of northern European descent. Decades of study have been directed toward a molecular understanding of
Zhe Zhang, Fangyu Liu, Jue Chen
semanticscholar   +1 more source

Quasimolecular structure in elastic O16 + O16 scattering [PDF]

open access: yes, 2006
It is suggested that the experimentally observed intermediate structure in the cross section of elastic O16 + O16 scattering is due to quasibound molecular states of the ion-ion system while the gross structure originates from virtually bound molecular ...
Greiner, Walter   +2 more
core  

Distinctive dielectric properties of nematic liquid crystal dimers [PDF]

open access: yes, 2017
We provide an overview of the effect of the molecular structure on the dielectric properties of dimers exhibiting nematic and twist-bend nematic phases with special focus on how the conformational distribution changes are reflected by the dielectric ...
de la Fuente, Maria del Rosario   +7 more
core   +2 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

RuvC uses dynamic probing of the Holliday junction to achieve sequence specificity and efficient resolution

open access: yesNature Communications, 2019
Holliday junctions (HJs) are four-way DNA structures that occur in DNA repair by homologous recombination which are removed by nucleases such as RuvC. Here the authors provide structural and biochemical details on the steps required for the completion of
Karolina Maria Górecka   +5 more
doaj   +1 more source

Rovibrational eigenenergy structure of the [H,C,N] molecular system [PDF]

open access: yes, 2011
The vibrational-rotational eigenenergy structure of the [H,N,C] molecular system is one of the key features needed for a quantum mechanical understanding of the HCN reversible arrow HNC model reaction. The rotationless vibrational structure corresponding
Mellau, Georg Ch.
core   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

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