Results 71 to 80 of about 19,935,117 (378)

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Observation of a shape resonance of the positronium negative ion

open access: yesNature Communications, 2016
The Positronium negative ion is formed by two electrons bound to a positron, and experimental investigations of its states and energy levels are difficult due to its short lifetime.
Koji Michishio   +8 more
doaj   +1 more source

Aerosol particle molecular spectroscopy [PDF]

open access: yes, 1985
The molecular spectroscopy of a solution particle by structure resonance modulation spectroscopy is discussed [S. Arnold and A. B. Pluchino, "Infrared Spectrum of a Single Aerosol Particle by Photothermal Modulation of Structure Resonances," Appl.
Arnold, S., Murphy, E. K., Sageev, G.
core   +1 more source

Hydrogen-bonded frameworks for molecular structure determination

open access: yesNature Communications, 2019
Single crystal X-ray diffraction is arguably the most definitive method for molecular structure determination, but the inability to grow suitable single crystals can frustrate conventional X-ray diffraction analysis.
Yuantao Li   +6 more
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

RuvC uses dynamic probing of the Holliday junction to achieve sequence specificity and efficient resolution

open access: yesNature Communications, 2019
Holliday junctions (HJs) are four-way DNA structures that occur in DNA repair by homologous recombination which are removed by nucleases such as RuvC. Here the authors provide structural and biochemical details on the steps required for the completion of
Karolina Maria Górecka   +5 more
doaj   +1 more source

Unique adipose tissue invariant natural killer T cell subpopulations control adipocyte turnover in mice

open access: yesNature Communications, 2023
Adipose tissue invariant natural killer T (iNKT) cells are a crucial cell type for adipose tissue homeostasis in obese animals. However, heterogeneity of adipose iNKT cells and their function in adipocyte turnover are not thoroughly understood.
Sang Mun Han   +15 more
doaj   +1 more source

Structure and permeability of ion-channels by integrated AFM and waveguide TIRF microscopy. [PDF]

open access: yes, 2014
Membrane ion channels regulate key cellular functions and their activity is dependent on their 3D structure. Atomic force microscopy (AFM) images 3D structure of membrane channels placed on a solid substrate.
Arce, Fernando Teran   +5 more
core   +2 more sources

CCT4 promotes tunneling nanotube formation

open access: yesFEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto   +3 more
wiley   +1 more source

Differentiation between enamines and tautomerizable imines in the oxidation reaction with TEMPO

open access: yesNature Communications, 2018
Tautomerization of imines into enamines is the basis of their similar reactivity; however, minor structural changes may lead to different outcomes. Here, the authors show that the reaction of cyclohexanone and amines in presence of TEMPO affords either α-
Xiaoming Jie   +5 more
doaj   +1 more source

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