Results 71 to 80 of about 122,210 (312)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Evaluation of customised lineage-specific sets of MIRU-VNTR loci for genotyping Mycobacterium tuberculosis complex isolates in Ghana [PDF]

, 2014
Different combinations of variable number of tandem repeat (VNTR) loci have been proposed for genotyping Mycobacterium tuberculosis complex (MTBC). Existing VNTR schemes show different discriminatory capacity among the six human MTBC lineages.
Michael Selasi Nyaho (542676), Yeboah-Manu, Dorothy, Borrell, Sonia, Adwoa Asante-Poku, Michael Selasi Nyaho, Sebastien Gagneux (149824), Iñaki Comas (57109), Dorothy Yeboah-Manu (120059), Gagneux, Sebastien, Adwoa Asante-Poku (335717), Sebastien Gagneux, Sonia Borrell (149821), Comas, Iñaki, Dorothy Yeboah-Manu, Nyaho, Michael Selasi, Sonia Borrell, Asante-Poku, Adwoa, Iñaki Comas   +17 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Genome-scale multilocus microsatellite typing of Trypanosoma cruzi discrete typing unit I reveals phylogeographic structure and specific genotypes linked to human infection. [PDF]

, 2009
Trypanosoma cruzi is the most important parasitic infection in Latin America and is also genetically highly diverse, with at least six discrete typing units (DTUs) reported: Tc I, IIa, IIb, IIc, IId, and IIe.
Torrico, Faustino, Valente, Vera, Lewis, Michael D., Llewellyn Martin S., Valente Vera, Jorge Vargas, Gaunt Michael W., Valente, Sebastiao A., Carrasco, Hernan J, Yeo, Matthew, Vera Valente, Michael A Miles, Miles Michael A., Gaunt, Michael W., Hernan J Carrasco, Miles, Michael A., Gaunt, Michael W, Carrasco, Hector Jeronimo, Vargas, Jorge, Torrico Faustino, Yeo Matthew, Michael D Lewis, Carrasco, Hernan J., Diosque Patricio, Valente Sebastiao A., Matthew Yeo, Vargas Jorge, Diosque, Patricio, Patricio Diosque, Llewellyn, Martin S, Martin S Llewellyn, Sebastiao A Valente, Miles, Michael A, Faustino Torrico, Lewis, Michael D, Carrasco Hernan J., Llewellyn, Martin S., Michael W Gaunt, Valente, Sebastiao A, Lewis Michael D.   +39 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Novel multilocus sequence typing scheme reveals high genetic diversity of human pathogenic members of the Fusarium incarnatum-F. equiseti and F. chlamydosporum species complexes within the United States

, 2009
Species limits within the clinically important Fusarium incarnatum-F. equiseti and F. chlamydosporum species complexes (FIESC and FCSC, respectively) were investigated using multilocus DNA sequence data.
Sutton, D.A., Geiser, D.M., Crous, P.W., O'Donnell, K., Rinaldi, M.G., Gueidan, C.   +5 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Delineating the evolutionary pathway to multidrug-resistant outbreaks of a Mycobacterium tuberculosis L4.1.2.1/Haarlem sublineage

International Journal of Infectious Diseases
Objectives: We sought to capture the evolutionary itinerary of the Mycobacterium tuberculosis L4.1.2.1/Haarlem sublineage in northern Tunisia, where it caused a major multidrug-resistant (MDR) tuberculosis outbreak in a context strictly negative for HIV ...
Naira Dekhil, Helmi Mardassi
doaj   +1 more source

Assessment of the use and need for an integrated molecular surveillance of tuberculosis: an online survey in Germany

BMC Public Health, 2019
Background The implementation of an integrated molecular surveillance (IMS) of tuberculosis (TB) is of high priority for TB control. IMS is defined as the systematic inclusion of molecular typing results in the national TB surveillance system.
Andrea Sanchini, Marta Andrés, Lena Fiebig, Stefan Albrecht, Barbara Hauer, Walter Haas   +5 more
doaj   +1 more source

Molecular Typing ofBorrelia burgdorferi [PDF]

Current Protocols in Microbiology, 2014
AbstractBorrelia burgdorferisensu lato is a group of spirochetes belonging to the genusBorreliain the family of Spirochaetaceae. The spirochete is transmitted between reservoirs and hosts by ticks of the family Ixodidae. Infection withB. burgdorferiin humans causes Lyme disease or Lyme borreliosis.
Guiqing, Wang, Dionysios, Liveris, Priyanka, Mukherjee, Sabrina, Jungnick, Gabriele, Margos, Ira, Schwartz   +5 more
openaire   +2 more sources