Results 81 to 90 of about 122,210 (312)

A Single Multilocus Sequence Typing (MLST) scheme for seven pathogenic Leptospira Species

, 2012
This study was funded by the Wellcome Trust. BGS and DMA were funded by Wellcome Trust grant 089472. SJP receives support from the NIHR Cambridge Biomedical Research CentreBackground: The available Leptospira multilocus sequence typing (MLST) scheme ...
Taylor, K, Cuicai Zhang (276536), Hoffmaster, Alex R., Chantratita, Narisara, Spratt, BG, Aanensen, David M., Amornchai, P., Lee D Smythe, Hoffmaster, AR, Galloway, R., Cuicai Zhang, Rudy A Hartskeerl, Alex R Hoffmaster, Feil, Edward J., Jiang, X, Taylor, K., Rudy A. Hartskeerl (94597), Day, N.P., Feil, E.J., Narisara Chantratita, Jiang, X., Holden, Matthew, Sharon J. Peacock (35782), Brian G. Spratt (10001), David M Aanensen, Chantratita, N., Thaipadungpanit, J, Boonsilp, S., Hartskeerl, Rudy A., Bailey, Mark S., Sharon J Peacock, Xiugao Jiang (276537), Amornchai, Premjit, Aanensen, D.M., Renee Galloway (276539), Narisara Chantratita (33898), Taylor, Kyle, Premjit Amornchai, Holden, MT, Koizumi, N., Bailey, MS, Mark S. Bailey (101757), Edward J Feil, Amornchai, P, Boonsilp, Siriphan, Nobuo Koizumi, Smythe, Lee D., Siriphan Boonsilp (276535), Lee D. Smythe (35773), Smythe, LD, Bailey, M.S., Day, Nicholas, Kyle Taylor (377049), Zhang, C, Jiang, Xiugao, Janjira Thaipadungpanit (35771), Day, Nicholas P., Siriphan Boonsilp, Galloway, R, Chantratita, N, Premjit Amornchai (247975), Holden, Matthew T. G., Edward J. Feil (35780), Peacock, Sharon J., Thaipadungpanit, J., Peacock, SJ, Wuthiekanun, V, Hartskeerl, RA, Vanaporn Wuthiekanun (35772), Craig, S., Galloway, Renee, Zhang, C., Holden, M.T.G., Craig, Scott, Scott Craig, Brian G Spratt, Hoffmaster, A.R., Holden, MTG, Feil, EJ, Matthew T G Holden, Boonsilp, S, Peacock, S.J., Matthew T. G. Holden (130258), Koizumi, N, Spratt, B.G., Renee Galloway, Wuthiekanun, V., Nicholas P. Day (160727), Koizumi, Nobuo, Nobuo Koizumi (276538), Aanensen, DM, Day, NP, David M. Aanensen (10000), Wuthiekanun, Vanaporn, Hartskeerl, R.A., Kyle Taylor, Spratt, Brian G., Janjira Thaipadungpanit, Vanaporn Wuthiekanun, Smythe, L.D., Nicholas P Day, Xiugao Jiang, Alex R. Hoffmaster (276540), Thaipadungpanit, Janjira, Mark S Bailey, Zhang, Cuicai, Scott Craig (276541), Craig, S   +107 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

On the onset and dispersal of a major MDR TB clone among HIV-negative patients, Tunisia

Antimicrobial Resistance and Infection Control
Background To carry out a whole genome sequencing (WGS)-based investigation on the emergence and spread of the largest multidrug-resistant tuberculosis (MDR TB) outbreak that has been thriving among HIV-negative patients, Tunisia, since the early 2000s ...
Naira Dekhil, Helmi Mardassi
doaj   +1 more source

Physicochemical Characteristics and Microbiological Quality of Honey Produced in Benin

Journal of Food Quality, 2018
Honey is a very complex biological product. It has great diversity, giving it a multitude of properties, both nutritionally and therapeutically. This study aimed to study the physicochemical and microbiological characteristics of honeys collected during ...
François Ezin Azonwade, Armand Paraïso, Cokou P. Agbangnan Dossa, Victorien T. Dougnon, Christine N’tcha, Wassiyath Mousse, Lamine Baba-Moussa   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

A combined molecular typing approach does not discriminate Legionella pneumophila serogroup 1 strains of a predominant sequence-based type in Palermo, Italy

Journal of Infection and Public Health, 2009
Summary: The sequence-based type 1,4,3,1,1,1 of Legionella pneumophila sg.1 is predominant in the Palermo city environment since several years. In this study, extended sequence-based typing and pulsed field gel electrophoresis were used in a combined ...
Celestino Bonura, Caterina Mammina, Antonietta Vella, Santina Belfiore, Alfredo Chiarini, Anna Giammanco   +5 more
doaj   +1 more source

Cost-effectiveness and efficacy of spa, SCCmec, and PVL genotyping of methicillin-resistant Staphylococcus aureus as compared to pulsed-field gel Electrophoresis. [PDF]

PLoS ONE, 2013
Pulsed-field gel electrophoresis (PFGE) is a valuable molecular typing assay used for methicillin-resistant Staphylococcus aureus (MRSA) surveillance and genotyping. However, there are several limitations associated with PFGE.
Vincent Li, Linda Chui, Lisa Louie, Andrew Simor, George R Golding, Marie Louie   +5 more
doaj   +1 more source

Use of AFLP and PFGE to discriminate between Salmonella enterica serovar Typhimurium DT126 isolates from separate food-related outbreaks in Australia

, 2005
In 2001 Salmonella enterica serovar Typhimurium definitive phage-type (DT) 126 was isolated at higher frequency in Australia compared to other S. Typhimurium phage types and in comparison to previous years.
Heuzenroeder, M., Ross, I.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source