Results 91 to 100 of about 122,210 (312)

Understanding the molecular epidemiology of the footrot pathogen Dichelobacter nodosus to support control and eradication programs

, 2010
The Gram-negative anaerobe Dichelobacter nodosus is the primary etiologic agent of ovine footrot. Few studies of the genetic diversity and epidemiology of D. nodosus have been done, despite the economic cost and welfare implications of the disease.
Pitman, D., D. J. Hampson, Palmer, M., Hampson, D.J., N. B. Buller, Ashley, P., D. Pitman, R. B. Richards, Buller, N. B., Richards, R. B., P. Ashley, M. Palmer   +11 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Comparative microsatellite typing of new world leishmania infantum reveals low heterogeneity among populations and its recent old world origin. [PDF]

, 2011
Leishmania infantum (syn. L. chagasi) is the causative agent of visceral leishmaniasis (VL) in the New World (NW) with endemic regions extending from southern USA to northern Argentina.
Michael A. Miles, Thierry Wirth, Alam, MZ,, Ferreira, Gabriel Eduardo M, Kuhls Katrin, Kuhls, Katrin, Alam Mohammad Zahangir, Mauricio, Isabel L., Oddone Rolando, Gabriel Eduardo M Ferreira, Schönian Gabriele, M. Dora Feliciangeli, Michael A Miles, Feliciangeli, M. Dora, Cupolillo Elisa, Miles Michael A., Miles, Michael A., Alam, Mohammad Zahangir, Isabel L Mauricio, Oddone, Rolando, Isabel L. Mauricio, M Dora Feliciangeli, Mohammad Zahangir Alam, Ferreira Gabriel Eduardo M., Kuhls , K,, Wirth Thierry, Cupolillo, Elisa, Mauricio, Isabel Larguinho, Katrin Kuhls, Mauricio, Isabel L, Wirth, Thierry, Feliciangeli M. Dora, Ferreira, Gabriel Eduardo M., Miles, Michael A, Gabriel Eduardo M. Ferreira, Rolando Oddone, Feliciangeli, M Dora, Mauricio Isabel L., Gabriele Schönian, Elisa Cupolillo, Schönian, Gabriele   +40 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Assessment of antimicrobial and anti-biofilm activities of lemongrass and bay leaf extracts on microorganisms from fermented cereal-based porridges in northern Benin

Scientific African
Lemongrass (Cymbopogon citratus) and bay leaf (Laurus nobilis) are condiments in food processing. This study aimed to assess the antimicrobial and anti-biofilm activities of lemongrass and bay leaf extract on the microorganisms isolated from cereal-based
Rachidatou Karimou, Hafiz A. Salami, Essé Agossou, Bawa Boya, Funkè F. Assouma, Boni Orou Marius Bio Bouko, Eugène S. Attakpa, Lamine Baba-Moussa, Haziz Sina   +8 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Incidence and spectrum of sporadic Creutzfeldt-Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification [PDF]

, 2009
Six subtypes of sporadic Creutzfeldt-Jakob disease with distinctive clinico-pathological features have been identified largely based on two types of the abnormal prion protein, PrPSc, and the methionine (M)/valine (V) polymorphic codon 129 of the prion ...
Maurizio Pocchiari, Roncaroli F, Cras, Patrick, Patrich Cras, Anna Ladogana, Giese, Armin, Cras, Patrich, Pocchiari M, Ladogana, Anna, Federico Roncaroli, Ladogana A, Bernardino Ghetti, Jan P. M. Langeveld, Strammiello, R., Zerr, I., Ghetti, B., Ghetti B, Roncaroli, Federico, Pocchiari, Maurizio, Langeveld, Jan P.M., Inga Zerr, Cras, P., Notari, Silvio, Cras P, Giese, A., Roncaroli, F., Parchi, Piero, Notari, S., Kretzschmar H, Langeveld JP, Rosaria Strammiello, Ghetti, Bernardino, Zerr, Inga, Kretzschmar, Hans A., Armin Giese, Parchi, P., Capellari, S., Hans Kretzschmar, Notari S, Pocchiari, M., Kretzschmar, Hans, Ladogana, A., Giese A, Langeveld, J.P.M., Capellari, Sabina, Strammiello, Rosaria, Piero Parchi, Silvio Notari, Zerr I, Langeveld, Jan P. M., Kretzschmar, H., Sabina Capellari   +51 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Integration of molecular typing results into tuberculosis surveillance in Germany-A pilot study.

PLoS ONE, 2017
An integrated molecular surveillance for tuberculosis (TB) improves the understanding of ongoing TB transmission by combining molecular typing and epidemiological data. However, the implementation of an integrated molecular surveillance for TB is complex
Marta Andrés, Elke Göhring-Zwacka, Lena Fiebig, Martin Priwitzer, Elvira Richter, Sabine Rüsch-Gerdes, Walter Haas, Stefan Niemann, Bonita Brodhun   +8 more
doaj   +1 more source

Development of a multilocus microsatellite typing approach for discriminating strains of Leishmania (Viannia) species.

, 2009
A multilocus microsatellite typing (MLMT) approach based on the analysis of 15 independent loci has been developed for the discrimination of strains belonging to different Viannia species.
Espinosa, Diego, Oddone, Rolando, Arevalo, Jorge, Mauricio, Isabel, Schweynoch, Carola, Sousa, Cintia dos Santos de, Kuhls, Katrin, de Sousa, Cintia dos Santos, Cupolillo, Elisa, Schönian, Gabriele, Noyes, Harry   +10 more
core   +1 more source