Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Apollo 15 rake sample microbreccias and non-mare rocks: Bulk rock, mineral and glass electron microprobe analyses [PDF]
Quantitative electron microprobe data of Apollo 15 nonmare rake samples are presented. Bulk analyses of lithic fragments in the nomare rocks (expressed in oxide weight-percent) and the corresponding CIPW molecular norms are given.
Bunch, T. E. +6 more
core +1 more source
Low Molecular Weight Heparin and Unfractionated Heparin Are Both Effective at Accelerating Pulmonary Vascular Maturation in Neonatal Rabbits [PDF]
, 2003 Stacy B. O’Blenes +6 more
openalex +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
The Molecular Weight of Trypsinogen
Journal of Biological Chemistry, 1961 C M, KAY, L B, SMILLIE, F A, HILDERMAN
openaire +2 more sources
The Molecular Weights of the Triarylmethyls [PDF]
Proceedings of the National Academy of Sciences, 1917 M, Gomberg, C S, Schoepfle
openaire +2 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Weight Effect on Local Motion of Polystyrene Studied by the Fluorescence Depolarization Method [PDF]
, 1999 Jun‐ichi Horinaka +3 more
openalex +1 more source
Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma
Molecular Oncology, EarlyView.PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga +2 more
wiley +1 more source
High molecular weight gDNA extraction after Mayjonade et al. optimised for eucalyptus for nanopore sequencing v9 [PDF]
, 2017 Miriam Schalamun, Benjamin Schwessinger
openalex +1 more source