Results 41 to 50 of about 2,997,351 (334)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Process for preparation of high-molecular- weight polyaryloxysilanes Patent [PDF]

open access: yes, 1968
Process for preparing high molecular weight polyaryloxysilanes from lower molecular weight ...
Dunnavant, W. R.
core   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Process of end-capping a polyimide system [PDF]

open access: yes, 1985
A process of endcapping a polyimide system with an endcapping agent in order to achieve a controlled decrease in molecular weight and melt viscosity along with predictable fracture resistance of the molded products is disclosed.
Burks, H. D., Stclair, T. L.
core   +1 more source

Phase separation effects and the nematic-isotropic transition in polymer and low molecular weight liquid crystals doped with nanoparticles [PDF]

open access: yes, 2013
Properties of the nematic–isotropic phase transition in polymer and low molecular weight liquid crystals doped with nanoparticles have been studied both experimentally and theoretically in terms of molecular mean-field theory.
Alexey S. Merekalov   +45 more
core   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Accurate molecular recognition from the lowest unoccupied molecular orbital

open access: yesScientific Reports
The quantification of the lowest unoccupied molecular orbital level (LUMO) for molecular semiconductors is of great importance, because it determines the charge transport process and hence the performances of diverse electronic devices.
Xuehua Zhou, Shixing Yang, Chao Han
doaj   +1 more source

Radical scavenging activity of crude polysaccharides from Camellia sinensis [PDF]

open access: yesArchives of Biological Sciences, 2011
A preparation of crude polysaccharides (TPS) was isolated from Camellia sinensis by precipitation and ultrafiltration. TPS1, TPS2, and TPS3 had molecular weights of 240, 21.4, and 2.46 kDa, respectively.
Yang Fan, Yang Zhiwei, Xiao Jianbo
doaj   +1 more source

A Study of Dual Polymer Retention Aids for the Retention on Titanium Dioxide Using the Dynamic Drainage Jar, Minidrinier, and Handsheets [PDF]

open access: yes, 1978
Two types of dual polymer retention aid systems, a low molecular weight, high charge density, cationic polyamine with a high molecular weight, low charge density, cationic polyacrylamide, and the same polyamine with a high molecular weight, highly ...
Null, David E.
core   +1 more source

Characterization of a Second Bovine Rotavirus Serotype [PDF]

open access: yes, 1987
Bovine rotavirus (BRV) V 1005 was characterized by two-way cross-neutralization tests as a second serotype of BRV. Virions and inner shell particles of 65 nm and 55 nm diameter respectively, and empty capsids of 65 nm and 55 nm diameter were separated by
Büssow, Harald   +4 more
core   +1 more source

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