Results 91 to 100 of about 3,473,423 (297)

Pathways and molecules for overcoming immunotolerance in metastatic gastrointestinal tumors

Frontiers in Immunology
Worldwide, gastrointestinal (GI) cancer is recognized as one of the leading malignancies diagnosed in both genders, with mortality largely attributed to metastatic dissemination.
Qixin Gan, Yue Li, Yuejun Li, Haifen Liu, Daochuan Chen, Lanxiang Liu, Churan Peng   +6 more
doaj   +1 more source

Electronic friction near metal surfaces: a case where molecule-metal couplings depend on nuclear coordinates

, 2016
We derive an explicit form for the electronic friction as felt by a molecule near a metal surface for the general case that molecule-metal couplings depend on nuclear coordinates.
Dou, Wenjie, Subotnik, Joseph E.
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Effect of Molecules’ Physicochemical Properties on Whey Protein/Alginate Hydrogel Rheology, Microstructure and Release Profile

Pharmaceutics
The encapsulation of molecules with different physicochemical properties (theophylline, blue dextran, salicylic acid and insulin) in whey protein (WP) and alginate (ALG) microparticles (MP) for oral administration was studied.
A. Delanne-Cuménal, E. Lainé, V. Hoffart, V. Verney, G. Garrait, E. Beyssac   +5 more
doaj   +1 more source

Site-selective adsorption of naphthalene-tetracarboxylic-dianhydride on Ag(110): First-principles calculations

, 2006
The mechanism of adsorption of the 1,4,5,8-naphthalene-tetracarboxylic-dianhydride (NTCDA) molecule on the Ag(110) surface is elucidated on the basis of extensive density functional theory calculations.
Alexis Baratoff, Audrius Alkauskas, C. Bruder, D. Gador, E. Umbach, F. S. Tautz, F. S. Tautz, I. G. Hill, M. Scheffler, R. Foster, R. M. Martin, S. Picozzi, S. R. Forrest, W. Koch, X. Crispin, X.-Y. Zhu   +15 more
core   +1 more source

Improved methods for predicting peptide binding affinity to MHC class II molecules [PDF]

, 2018
Kamilla Kjærgaard Jensen, Massimo Andreatta, Paolo Marcatili, Søren Buus, Jason Greenbaum, Yan Zhen, Alessandro Sette, Bjoern Peters, Morten Nielsen   +8 more
openalex   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Isoprene: An Antioxidant to Guard Plants against Stress

International Journal of Plant Biology
Isoprene, a lipophilic and unstable compound with the chemical formula C5H8, is transported to plant chloroplasts via the 2-C-methyl-d-erythritol 4-phosphate (MEP) pathway, which relies on photosynthesis. Although only about 20% of terrestrial plants can
Perumalla Srikanth, Ann Maxton, Sam A. Masih, Adriano Sofo, Nafees A. Khan   +4 more
doaj   +1 more source

Pathological mutations differentially affect the self-assembly and polymerisation of the innate immune system signalling adaptor molecule MyD88

BMC Biology, 2018
Background Higher-order self-assembly of proteins, or “prion-like” polymerisation, is now emerging as a simple and robust mechanism for signal amplification, in particular within the innate immune system, where the recognition of pathogens or danger ...
Ailís O’Carroll, Brieuc Chauvin, James W. P. Brown, Ava Meagher, Joanne Coyle, Jurgen Schill, Akshay Bhumkhar, Dominic J. B. Hunter, Thomas Ve, Bostjan Kobe, Emma Sierecki, Yann Gambin   +11 more
doaj   +1 more source

Behavior of molecules and molecular ions near a field emitter [PDF]

, 2016
Baptiste Gault, David W. Saxey, Michael Ashton, Susan B. Sinnott, Ann N. Chiaramonti, Michael P. Moody, Daniel K. Schreiber   +6 more
openalex   +1 more source