Results 91 to 100 of about 5,095,036 (399)
Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists
Science, 2010 Regulating Migration The migration of cells around the body is an important factor in cancer development and the establishment of infection. Movement is induced by small proteins called chemokines, and so for a specific function, migration is controlled ...
Beili Wu +14 more
semanticscholar +1 more source
, 2011 Using first-principles calculations, we systematically study the potential energy surfaces and dissociation processes of the hydrogen molecule on the Mg(0001) surface.
Amonenko V +9 more
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Journal of Nucleic Acids, 2022 A high volume of diagnostic tests is needed during the coronavirus disease 2019 (COVID-19) pandemic to obtain representative results. These results can help to design and implement effective policies to prevent the spread of severe acute respiratory ...
Almando Geraldi +2 more
doaj +1 more source
Human colon organoid differentiation from induced pluripotent stem cells using an improved method
FEBS Letters, EarlyView.We compared established protocols to differentiate induced pluripotent stem cells into colon organoids and found that activation of bone morphogenetic protein 2 signaling induced gene expression of colon‐specific markers. Adenovirus‐mediated transduction of the transcription factors HOXD13 or SATB2 further enhanced colonic gene expression, suggesting ...
I‐Ting Lee +4 more
wiley +1 more source
Microwave traps for cold polar molecules [PDF]
, 2004 We discuss the possibility of trapping polar molecules in the standing-wave electromagnetic field of a microwave resonant cavity. Such a trap has several novel features that make it very attractive for the development of ultracold molecule sources.
arxiv +1 more source
Topological states of the diatomic linear chain: effect of impedance matching to the fixed ends
New Journal of Physics, 2020 The diatomic linear chain with nearest-neighbor spring constants C _1 and C _2 has topologically different bulk states for C _1 ≷ C _2 . A finite chain of N unit cells and fixed ends (the first and last spring is C _1 ) exhibits two topological end ...
Marius Grundmann
doaj +1 more source
Atom-molecule equilibration in a degenerate Fermi gas with resonant interactions
, 2004 We present a nonequilibrium kinetic theory describing atom-molecule population dynamics in a two-component Fermi gas with a Feshbach resonance. Key collision integrals emerge that govern the relaxation of the atom-molecule mixture to chemical and thermal
C W Clark +14 more
core +1 more source
Nature Physics, 2019 The demonstration of high-resolution spectroscopy of Sr2 molecules trapped in an optical lattice at the ‘magic’ wavelength opens the way to precision control of molecular excitations.
openaire +3 more sources
FEBS Letters, EarlyView.Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard +7 more
wiley +1 more source