Results 101 to 110 of about 3,473,423 (297)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

As4Se4 crystal versus As4Se4 molecule: A plane wave DFT study of the geometric and electronic structure

Physics of Complex Systems
Сhalcogenide crystals reveal a wide range of changes in chemical and physical properties under band gap light illumination. A majority of these properties are determined by the electronic structure.
Антон Андреевич Гавриков, Владимир Георгиевич Кузнецов, Владимир Андреевич Трепаков   +2 more
doaj   +1 more source

Tuning the Magnetic Anisotropy at a Molecule-Metal Interface [PDF]

, 2015
Kaushik Bairagi, Amandine Bellec, Vincent Repain, Cyril Chacon, Yann Girard, Y. Garreau, Jérôme Lagoute, Sylvie Rousset, Romain Breitwieser, Yu-Cheng Hu, Yen Cheng Chao, Woei Wu Pai, Dongzhe Li, Alexander Smogunov, Cyrille Barreteau   +14 more
openalex   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

The Shine-Dalgarno sequence of riboswitch-regulated single mRNAs shows ligand-dependent accessibility bursts

Nature Communications, 2016
In response to intracellular signals, bacterial translational riboswitches embedded in mRNAs can regulate gene expression through inhibition of translation initiation.
Arlie J. Rinaldi, Paul E. Lund, Mario R. Blanco, Nils G. Walter   +3 more
doaj   +1 more source

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

FEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Photodegradation of α-Pinene Secondary Organic Aerosol Dominated by Moderately Oxidized Molecules [PDF]

, 2021
Veronika Pospíšilová, David M. Bell, Houssni Lamkaddam, Amélie Bertrand, Liwei Wang, Deepika Bhattu, Xueqin Zhou, Josef Dommen, Andrê S. H. Prévôt, Urs Baltensperger, Imad El Haddad, Jay G. Slowik   +11 more
openalex   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Drug selection for inner ear therapy

Frontiers in Pharmacology
IntroductionOne of the primary tenets in pharmacotherapy is that the applied drug must reach the target tissue at therapeutic concentration. For many therapies intended to treat hearing disorders it has become apparent that we have failed to achieve this
Alec N. Salt, Jeremy G. Turner
doaj   +1 more source