Results 101 to 110 of about 3,518,193 (347)

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

CD molecules 2006 — Human cell differentiation molecules

Journal of Immunological Methods, 2007
The Human Leucocyte Differentiation Antigens Workshops (HLDA) have since 1984 provided a forum for the characterization and study of leucocyte surface molecules and antibodies against them. HLDA devised the CD nomenclature, which is sanctioned by IUIS.
ZOLA H, SWART B, BANHAM A, BARRY S, BEARE A, BENSUSSAN A, BOUMSELL L, D. BUCKLEY C, BÜHRING HJ, CLARK G, ENGEL P, FOX D, JIN BQ, MACARDLE PJ, MALAVASI, Fabio, MASON D, STOCKINGER H, YANG X.   +17 more
openaire   +3 more sources

Drug selection for inner ear therapy

Frontiers in Pharmacology
IntroductionOne of the primary tenets in pharmacotherapy is that the applied drug must reach the target tissue at therapeutic concentration. For many therapies intended to treat hearing disorders it has become apparent that we have failed to achieve this
Alec N. Salt, Jeremy G. Turner
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Surface state engineering of molecule–molecule interactions

Physical Chemistry Chemical Physics, 2012
Engineering the electronic structure of organics through interface manipulation, particularly the interface dipole and the barriers to charge carrier injection, is of essential importance to improved organic devices. This requires the meticulous fabrication of desired organic structures by precisely controlling the interactions between molecules.
Rojas, Geoffrey, Simpson, Scott, Chen, Xumin, Kunkel, Donna A., Nitz, Justin, Xiao, Jie, Dowben, Peter A., Zurek, Eva, Enders, Axel   +8 more
openaire   +4 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Effect of ECAP and volume ultrasonic treatment on the corrosion resistance of magnesium [PDF]

BIO Web of Conferences
Magnesium and its alloys are promising materials for manufacturing bioresorbable implants. Various combinations of thermo-mechanical processing are used to improve the mechanical properties and corrosion resistance of magnesium alloys, forming the ...
Aksenov Denis, Nazarov Airat, Shishkunova Maria, Asfandiyarov Rashid, Sementeeva Yulia   +4 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Gate Coupling to Nanoscale Electronics

, 2009
The realization of single-molecule electronic devices, in which a nanometer-scale molecule is connected to macroscopic leads, requires the reproducible production of highly ordered nanoscale gaps in which a molecule of interest is electrostatically ...
A. T. Charlie Johnson, C. M. Lieber, Douglas R. Strachan, E. L. Wolf, J. D. Jackson, J. H. Stathis, M. Ohring, S. M. Sze, Sujit S. Datta   +8 more
core   +2 more sources