Results 41 to 50 of about 286,385 (277)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Infecções de tecidos moles

open access: yesMedicina, 2003
Nesta revisão são abordados a etiologia e os principais aspectos clínicos, dermatológicos e terapêuticos das infecções de tecidos moles e das síndromes infecciosas mediadas por toxinas.
Cacilda Silva Souza
doaj   +1 more source

Partial molar pregnancy with live fetus diagnosed on second trimester: a case report [PDF]

open access: yes, 2016
Hydatidiform mole is part of a group of diseases classified as gestational trophoblastic disease, which results from an aberrant fertilization. They are associated with an increase risk for the development of neoplasm, specifically choriocarcinoma, a ...
Cardoso, Rosete Maria Amorim Novais Nogueira   +4 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Hunter & Mole

open access: yes, 2013
We consider a variation of a cops and robbers game in which the cop---here referred to as "hunter"---is not constrained by the graph but must play in the dark against a "mole." We characterize the graphs---which we will call "hunter-win"---on which the hunter can guarantee capture of the mole in bounded time.
Komarov, Natasha, Winkler, Peter
openaire   +2 more sources

Norwich’s Entropy Theory: how not to go from abstract to actual [PDF]

open access: yes, 2011
Purpose – The purpose of this paper is to ask whether a first-order-cybernetics concept, Shannon’s Information Theory, actually allows a far-reaching mathematics of perception allegedly derived from it, Norwich et al.’s “Entropy Theory of Perception”.
Nizami, Lance
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

General method for the synthesis of enaminones via photocatalysis

open access: yesBeilstein Journal of Organic Chemistry
Enaminones are key intermediates in the synthesis of several derivatives with important applications in medicinal chemistry. Furthermore, many marketed drugs feature the enaminone structural moiety.
Paula Pérez-Ramos   +2 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Adiabatic Flame Temperature for Combustion of Methane II

open access: yesUndergraduate Journal of Mathematical Modeling: One + Two, 2013
We calculate the adiabatic flame temperature of a mixture of methane and oxygen in the presence of a diluent gas then determine the mole fractions of methane without respect to nitrogen and solve for the moles of oxygen present.
Rebeca Pupo
doaj   +1 more source

Home - About - Disclaimer - Privacy