Results 51 to 60 of about 51,668 (264)

Moles and Mole Control on British Farms, Amenities and Gardens after Strychnine Withdrawal

Animals, 2016
Moles are considered pests in Britain, but this issue has been little studied. Lower welfare standards have been tolerated for moles than for most other managed wild mammal species, as use of both the controversial poison, strychnine, and unregulated ...
Sandra E. Baker, Stephen A. Ellwood, Paul J. Johnson, David W. Macdonald   +3 more
doaj   +1 more source

Moles of a Substance per Cell Is a Highly Informative Dosing Metric in Cell Culture. [PDF]

PLoS ONE, 2015
The biological consequences upon exposure of cells in culture to a dose of xenobiotic are not only dependent on biological variables, but also the physical aspects of experiments e.g. cell number and media volume.
Claire M Doskey, Thomas J van 't Erve, Brett A Wagner, Garry R Buettner   +3 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

MOLES3: Implementing an ISO standards driven data catalogue

International Journal of Digital Curation, 2015
ISO19156 Observations and Measurements (O&M) provides a standardised framework for organising information about the collection of information about the environment.  Here we describe the implementation of a specialisation of O&M for environmental data,
Graham A Parton, Steven Donegan, Stephen Pascoe, Ag Stephens, Spiros Ventouras, Bryan N Lawrence   +5 more
doaj   +3 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Mole senses [PDF]

Current Biology, 2019
Many people are familiar with the meandering tunnels of moles, far fewer are familiar with the creatures that made them. Such secrecy is, of course, one of the great benefits of burrowing through the earth where few predators can follow. But it's not the only benefit. Soil contains a smorgasbord of nutritious invertebrate prey - hence all the tunneling.
openaire   +2 more sources

Expression of Epidermal Growth Factor Receptor (Egfr) in Mole Hydatidiforms, Exaggarated Placental Sites and Normal Placentas and Ki 67 in Mole Hydatidiforms and Normal Placentas

Gynecology Obstetrics & Reproductive Medicine, 2006
OBJECTIVE: The aim of this study is to find out differences between expression of EGFR (epidermal growth f actor receptor) and Ki 67 labeling index (LI) in complete, incomplete mole hydatidiforms, exaggareted placental sites and normal placentas.
Gökben Yıldırım Küpesiz, Hadice Elif Peştereli, Gülgün Erdoğan, Mehmet Şimşek, Fatma Şeyda Karaveli   +4 more
doaj  

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source