Results 51 to 60 of about 286,385 (277)

Moles of a Substance per Cell Is a Highly Informative Dosing Metric in Cell Culture. [PDF]

PLoS ONE, 2015
The biological consequences upon exposure of cells in culture to a dose of xenobiotic are not only dependent on biological variables, but also the physical aspects of experiments e.g. cell number and media volume.
Claire M Doskey, Thomas J van 't Erve, Brett A Wagner, Garry R Buettner   +3 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Challenging the Bredt’s rule in an acid catalyzed cationic cyclization to get bicyclo[3.3.1]nonane derivatives

Nature Communications
Vinyl carbocations are long known in chemistry but remain less explored than common sp²-hybridized carbocations, and their synthetic applications are limited.
Olaya García-Pedrero, Pilar Pardo, Nerea Alberro, Fernando P. Cossío, Félix Rodríguez   +4 more
doaj   +1 more source

A visual-display and storage device [PDF]

, 1972
Memory and display device uses cathodochromic material to store visual information and fast phosphor to recall information for display and electronic processing.
Bosomworth, D. R., Moles, W. H.
core   +1 more source

Analysis of the Efficacy of 5-Fluorouracil in the Treatment of Invasive Moles

Clinical and Experimental Obstetrics & Gynecology
Background: To evaluate the chemotherapy toxicity of 5-fluorouracil (5-FU) in the treatment of invasive moles. Methods: We conducted a retrospective study of therapeutic satisfaction, recurrence, and toxicity in 17 patients treated with 5-FU in the ...
Chunhua Liu, Peilin Ouyang, Yin Tao, Mingyu Xie   +3 more
doaj   +1 more source

Moles and Mole Control on British Farms, Amenities and Gardens after Strychnine Withdrawal

Animals, 2016
Moles are considered pests in Britain, but this issue has been little studied. Lower welfare standards have been tolerated for moles than for most other managed wild mammal species, as use of both the controversial poison, strychnine, and unregulated ...
Sandra E. Baker, Stephen A. Ellwood, Paul J. Johnson, David W. Macdonald   +3 more
doaj   +1 more source

De la psychologie du Kitsch en Côte d’Ivoire : pour une approche sociodynamique de la Culture ivoirienne [PDF]

Ziglôbitha, 2022
Résumé : Le titre de l’article est inspiré des travaux d’Abraham Moles. Il est célèbre pour avoir écrit La Psychologie du Kitsch. Dans son ouvrage, il présente le Kitsch comme le mot par lequel la société moderne occidentale se conçoit et se qualifie. En
Axel Richard EBA
doaj  

Predicting the impact of land use on the major element and nutrient fluxes in coastal Mediterranean rivers: The case of the Teˆt River (Southern France) [PDF]

, 2007
This study presents a detailed discrimination between the natural and anthropogenic sources of dissolved major elements in the Teˆt River, a typical small coastal river in the south of France.
Garcia-Esteves, Javier, Kerhervé, Philippe, Lespinas, Franck, Ludwig, Wolfgang, Probst, Jean-Luc   +4 more
core   +3 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source