Results 71 to 80 of about 68,250 (311)
AMA Journal of Ethics, 2004 Surgeons should not make medical decisions for a patient while the patient is under anesthesia. Virtual Mentor is a monthly bioethics journal published by the American Medical Association.
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Current Biology, 2019 Many people are familiar with the meandering tunnels of moles, far fewer are familiar with the creatures that made them. Such secrecy is, of course, one of the great benefits of burrowing through the earth where few predators can follow. But it's not the only benefit. Soil contains a smorgasbord of nutritious invertebrate prey - hence all the tunneling.
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Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
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Functional morphology of marsupial moles (Marsupialia: Notoryctidae)
, 2006 Marsupial moles (genus Notoryctes) are the most highly specialised burrowing marsupials. The specialisations of the appendicular musculo-skeletal system of the marsupial moles are extensive and widespread; the major alterations are concentrated in, but ...
Warburton, N.M.
core
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Sofocle, Sciri, fr. 555 R.2: una nuova proposta ecdotica e interpretativa
, 2021 Based on linguistic observations and previously unconsidered loci paralleli, this paper proposes a partially different critical text and interpretation of fr.
Francesco Moles
core
Sarcoma Epitelióide: análise de 15 casos tratados no INCA
Revista Brasileira de Cancerologia, 2004 Objetivo: Descrever os aspectos epidemiológicos, clínicos, anatomopatológicos e o tratamento dos pacientes com sarcoma epitelióide matriculados no Instituto Nacional de Câncer, comparando-os com os resultados da literatura. Pacientes e Método: Revisão do
Luiz Fernando Nunes +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source