Results 71 to 80 of about 51,668 (264)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Investigation of the role of exogenous use of sucrose as an osmoprotectant in increasing Azolla filiculoides resistance to air high temperature and salt stress

open access: yes‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2008
Influence of 2.75 to 11 moles sucrose as an exogenous osmoprotectant on salt stressed (7.8-9.1 and 18.2 ms/cm) and temperature stressed (42.36C) Azolla (A. filiculoides Lam.) was studied.
M. Asfia; A. Ghalavand; H. Heidari; Sh. Nezami; Gh. Normohammadi
doaj  

Comparing questionnaires across cultures: Using Mokken scaling to compare the Italian and English versions of the MOLES index

open access: yesNursing Open, 2019
Aim The aims of this study were (a) to translate the MOLES index from English to Italian and (ii) to compare the two versions using non‐parametric item response theory. Design An online survey was used to gather data. Methods Forward and back translation
Giuseppe Aleo   +9 more
doaj   +1 more source

Sarcoma Epitelióide: análise de 15 casos tratados no INCA

open access: yesRevista Brasileira de Cancerologia, 2004
Objetivo: Descrever os aspectos epidemiológicos, clínicos, anatomopatológicos e o tratamento dos pacientes com sarcoma epitelióide matriculados no Instituto Nacional de Câncer, comparando-os com os resultados da literatura. Pacientes e Método: Revisão do
Luiz Fernando Nunes   +5 more
doaj   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur   +5 more
wiley   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez   +5 more
wiley   +1 more source

D-Excess-LaA Production Directly from Biomass by Trivalent Yttrium Species

open access: yesiScience, 2019
Summary: D-lactic acid (D-LaA) synthesis directly from actual biomass via chemocatalytic conversion has shown high potential for satisfying its enormous demand in widespread applications.
Shuguang Xu   +5 more
doaj   +1 more source

Thermodynamic Pathways of Nonequilibrium Solidification in Wire‐Arc Additive Manufacturing Fe‐Based Multicomponent Alloy Structures

open access: yesAdvanced Engineering Materials, EarlyView.
Geometry‐driven thermal behavior in wire‐arc additive manufacturing (WAAM) influences microstructural evolution during nonequilibrium solidification of a chemically complex Fe–Cr–Nb–W–Mo–C nanocomposite system. By comparing different deposits configurations, distinct entropy–cooling rate correlations, segregation, and carbide evolution are revealed ...
Blanca Palacios   +5 more
wiley   +1 more source

Epoxidation of methyl esters derived from Jatropha oil: An optimization study

open access: yesGrasas y Aceites, 2013
The optimization of the epoxidation reaction of methyl esters obtained from Jatropha oil was appraised. Response surface methodology (RSM) based on a central composite rotatable design (CCRD) was employed for the experimental design.
M. Mushtaq   +6 more
doaj   +1 more source

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