Results 101 to 110 of about 173,148 (300)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Experimental Study on Flotation of a Molybdenum Mine in Inner Mongolia by LKD-3

Kuangchan zonghe liyong
In view of the problems of complex dissemination state, serious argillization and difficult to reduce tailings grade of a molybdenum mine in Inner Mongolia, LKD-3 collector was used to conduct the flotation test.
Ying LI, Hong LIU, Jian WANG, Yiwen MA, Xiaojun JIANG, Qi ZHANG, Bo CUI   +6 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Study and Application of BOF Steelmaking Steel Bearing Molybdenum by Molybdenum Trioxide to Replace Ferromolybdenum

Teshugang, 2017
The conditions of thermodynamics and kinetics for molybdenum trioxide reduced by main elements C, Si, Mn and Fe in BOF liquid are analyzed and the adding method of molybdenum trioxide during BOF steelmaking process is discussed.
李永超, 阎丽珍, 姬旦旦, 霍志斌   +3 more
doaj  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Preparation of Molybdenum Ore and Molybdenum Concentrate Reference Materials

Yankuang ceshi, 2013
Accurate analysis of chemical compositions is vital for exploration and comprehensive utilization of molybdenum minerals. Reference materials can provide criterion and technical support for the chemical composition analysis.
LIU Mei, CHENG Zhi-zhong, GU Tie-xin, HUANG Hong-ku, YAN Wei-dong, YANG Rong, PAN Han-jiang   +6 more
doaj  

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

The role of CO2 in the genesis of Dabie-type porphyry molybdenum deposits

Nature Communications
Porphyry-type molybdenum deposits, many of which are in China, supply most of the World’s molybdenum. Of particular importance are the molybdenum deposits located in the Qinling-Dabie region that are responsible for more than half of China’s molybdenum ...
Zi-Qi Jiang, Lin-Bo Shang, A. E. Williams-Jones, Xin-Song Wang, Li Zhang, Huai-Wei Ni, Rui-Zhong Hu, Xian-Wu Bi   +7 more
doaj   +1 more source

Selective Flotation of a Copper-molybdenum Bulk Concentrate from Xizang

Kuangchan zonghe liyong
This is an article in the field of mineral processing engineering. A technological mineralogical study was carried out on a copper-molybdenum bulk concentrate in Xizang.
Jinming GUO, Hongying YANG, Shiqi ZHANG, Linlin TONG, Zhenan JIN, Qin ZHANG   +5 more
doaj   +1 more source