Results 81 to 90 of about 140,903 (252)

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Molybdenum-Catalyzed Asymmetric Hydrogenation of Fused Arenes and Heteroarenes

The synthesis of enantioenriched molybdenum precatalysts for the asymmetric hydrogenation of substituted quinolines and naphthalenes is described. Three classes of pincer ligands with chiral substituents were evaluated as supporting ligands in the ...
Kurt Puentener (12890391), Paolo Tosatti (2186632), Tyler P. Pabst (7182011), Gabriele Hierlmeier (12244531), Peter Viereck (3714121), Paul J. Chirik (1311855)   +5 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Lowering the Mo limit for nitrogen fixation by Mo-nitrogenase

Communications Earth & Environment
Archean ocean marine primary productivity may have been limited by biologically available nitrogen. Due to low molybdenum abundances, early biological nitrogen fixation is thought to have relied on alternative nitrogenases that incorporate vanadium or ...
Zackry Stevenson, Dylan L. Schultz, Michelle Chamberlain, Kathryn Rico, Ariel Anbar, Anne E. Dekas, Elizabeth D. Swanner   +6 more
doaj   +1 more source

Early hydration and mechanical performance of composited cementitious system prepared from high temperature calcined molybdenum tailings

Case Studies in Construction Materials
To improve the recycling of solid waste and achieve the secondary utilization of waste resources, this study investigates the preparation of molybdenum tailings composited binders by high temperature calcination using molybdenum tailings, limestone ...
Jun Li, Zhenwei Yang, Qian Su, Chang Cai, Hesong Jin, Qingxin Xue, Ruizhu Tian, Jiao Liu, Lingkun Chen, Tianchun Wang, Tuan Ngo   +10 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Development and Utilization Status and the Future Demand Forecast of Molybdenum Resources in China

Kuangchan zonghe liyong
This is an article in the field of mining engineering. This article analyzes the present situation of molybdenum resource exploitation and utilization in China, and predicts the future demand formolybdenum resource in China.
Xiu WANG, Chonghao LIU, Anjian WANG, Jing LIU, Xiangying JIA   +4 more
doaj   +1 more source

Utilization of Molybdenum Tailings in Concrete Manufacturing: A Review

Applied Sciences, 2019
Dealing with mineral tailings is one of the most important topics for solving the environmental problems in the mining industry. Among the techniques converting stacked molybdenum tailings to reusable cleaner products, one of the most effective ones is ...
Shan Gao, Xiaowei Cui, Sumei Zhang
doaj   +1 more source

Molybdenum-Mediated Cleavage Reactions of Isoxazoline Rings Fused in Bicyclic Frameworks

, 2016
The molybdenum-mediated cleavage reactions of isoxazoline rings fused in bicyclic frameworks were investigated. A tandem N−O bond cleavage-retro aldol reaction of an isoxazoline ring fused in a bicyclic framework led to the cleavage of the bicyclic ...
Geoffrey K. Tranmer (2520547), William Tam (640256)   +1 more
core   +1 more source