Results 61 to 70 of about 266,479 (327)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
ESTIMATION OF INERTIA MOMENT OF CAR ENGINE MOVING PARTS [PDF]
Avtomobilʹnyj Transport (Harʹkov), 2018 Problem. To calculate the car dynamics, especially in urban conditions with frequent transitions to lower gears, the values of the inertia moment (MI) or the equivalent mass (EM) of the engine moving parts, brought to the crankshaft, are required ...
Rabinovich E., Zytsev Yu., Kalekin V.
doaj +1 more source
Relation between the moment of inertia and the k2 Love number of fluid extra-solar planets [PDF]
, 2023 Anastasia Consorzi +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
ESTIMATION OF MASS MOMENT OF INERTIA OF HUMAN BODY, WHEN BENDING FORWARD, FOR THE DESIGN OF A SELF-TRANSFER ROBOTIC FACILITY [PDF]
Journal of Engineering Science and Technology, 2016 Knowledge of Mass Moment of Inertia of human body and its segments are necessary for various problems in biomechanics and its applications. This paper focusses on the estimation of Moment of Inertia of a human body when bending forward, which is needed ...
R. HARI KRISHNAN +3 more
doaj
Influence of moment of inertia on electric power system security and stability control
The Journal of Engineering, 2018 The moment of inertia is the basic parameter of the generator and also the basic data of PSS parameter tuning. The parameter setting of PSS will increase the damping of the unit and improve the small disturbance stability of the system.
Xiaguang Ma +3 more
doaj +1 more source
The Moment of Inertia of the Binary Pulsar J0737-3039A: Constraining the Nuclear Equation of State
, 2004 We construct numerical models of the newly discovered binary pulsar J0737-3039A, both with a fully relativistic, uniformly rotating, equilibrium code that handles arbitrary spins and in the relativistic, slow-rotation approximation.
Chandrasekhar S. +5 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source