Results 51 to 60 of about 266,479 (327)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
, 2010 Neutron stars are the densest objects known in the Universe. Being the final product of stellar evolution, their internal composition and structure is rather poorly constrained by measurements.
Petri, J.
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Balance of the Inertial Force and Inertial Moment of Crank Group Mechanism
Jixie chuandong, 2016 The inertia force and the inertia moment of the crank group mechanism are analyzed based on its characteristics. The balancing conditions of the inertia force and the inertia moment of the crank group mechanism are given and a practical balancing method ...
Liu Yansong, Cao Jujiang
doaj
Determination of Equivalent Moment of Inertia of Flywheel for Inertial Endurance Test of Excavator Slewing System [PDF]
한국정밀공학회지, 2017 This study determined the equivalent moment of inertia of the upper rotating body of an excavator, for the inertial endurance test of an excavator slewing system.
Sang gon Moon +2 more
doaj +1 more source
Titan's Obliquity as evidence for a subsurface ocean?
, 2011 On the basis of gravity and radar observations with the Cassini spacecraft, the moment of inertia of Titan and the orientation of Titan's rotation axis have been estimated in recent studies.
Baland, Rose-Marie +3 more
core +1 more source
On Minimal Moment of Inertia Polyominoes [PDF]
, 2008 We analyze the moment of inertia I(S), relative to the center of gravity, of finite plane lattice sets S. We classify these sets according to their roundness: a set S is rounder than a set T if I(S) < I(T). We show that roundest sets of a given size are strongly convex in the discrete sense.
Srecko Brlek +2 more
openaire +1 more source
Methods for estimating moment of inertia of cricket bats [PDF]
, 2021 David Curtis, Ben Heller, Terry Senior
openalex +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source